Kumar, Ashok
first name: Ashok
last name: Kumar
coauthor of: Roy, Anirban
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full name: Ashok Kumar
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selected publications: Authorship 8792
selected publications: Authorship 8793
selected publications: Authorship 8794
selected publications: Authorship 8795
selected publications: Authorship 8796
selected publications: Authorship 8797
selected publications: Authorship 8798
selected publications: Authorship 8799
research areas: Muscle, Skeletal
research areas: Signal Transduction
research areas: Regeneration
research areas: Muscle Development
research areas: Endoribonucleases
research activities: Principal Investigator
mailing address: https://profilesrns.times.uh.edu/profile/172068
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Endoribonucleases
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number of authors: 6
number of publications: 9
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Regeneration
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number of authors: 8
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Muscle, Skeletal
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number of authors: 27
number of publications: 82
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https://profilesrns.times.uh.edu/profile/172068
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address line 1: 4800 Calhoun Rd
city: Houston
postal code: 77004
state or province: TX

Biology and Biochemistry
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Pharmacological and Pharmaceutical Sciences
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Miao, Lianjie
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Wu, Mingfu
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Gunaratne, Preethi
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Darabi, Radbod
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Schwartz, Robert
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Roy, Anirban
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Dryer, Stuart
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Biochemistry
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Cell and Molecular Biology
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College of Pharmacy
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Signal Transduction
MeSH DescriptorUI: D015398
MeSH semantic group name: Physiology
number of authors: 69
number of publications: 225
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Arizona State University (ASU)
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Santello, Marco
first name: Marco
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Metal chelate affinity precipitation of RNA and purification of plasmid DNA.
PubMed Identifier: 12889823
author list: Balan S, Murphy J, Galaev I, Kumar A, Fox GE, Mattiasson B, Willson RC
published in: Biotechnology letters
information resource reference: Metal chelate affinity precipitation of RNA and purification of plasmid DNA. Biotechnol Lett. 2003 Jul; 25(13):1111-6.
journal title abbreviation: Biotechnol Lett
publication date: 2003-07-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Single-nucleus transcriptomic analysis reveals the regulatory circuitry of myofiber XBP1 during regenerative myogenesis.
PubMed Identifier: 39650729
author list: Joshi AS, Castillo MB, Tomaz da Silva M, Vuong AT, Gunaratne PH, Darabi R, Liu Y, Kumar A
published in: iScience
information resource reference: Single-nucleus transcriptomic analysis reveals the regulatory circuitry of myofiber XBP1 during regenerative myogenesis. iScience. 2024 Dec 20; 27(12):111372.
journal title abbreviation: iScience
publication date: 2024-11-12T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

The IRE1a/XBP1 signaling axis drives myoblast fusion in adult skeletal muscle.
PubMed Identifier: 38982191
author list: Joshi AS, Tomaz da Silva M, Roy A, Koike TE, Wu M, Castillo MB, Gunaratne PH, Liu Y, Iwawaki T, Kumar A
published in: EMBO reports
information resource reference: The IRE1a/XBP1 signaling axis drives myoblast fusion in adult skeletal muscle. EMBO Rep. 2024 Aug; 25(8):3627-3650.
journal title abbreviation: EMBO Rep
publication date: 2024-07-09T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

?1 integrins regulate cellular behaviour and cardiomyocyte organization during ventricular wall formation.
PubMed Identifier: 38794925
author list: Miao L, Lu Y, Nusrat A, Zhao L, Castillo M, Xiao Y, Guo H, Liu Y, Gunaratne P, Schwartz RJ, Burns AR, Kumar A, DiPersio CM, Wu M
published in: Cardiovascular research
information resource reference: ?1 integrins regulate cellular behaviour and cardiomyocyte organization during ventricular wall formation. Cardiovasc Res. 2024 Sep 21; 120(11):1279-1294.
journal title abbreviation: Cardiovasc Res
publication date: 2024-09-21T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Fn14 promotes myoblast fusion during regenerative myogenesis.
PubMed Identifier: 37813488
author list: Tomaz da Silva M, Joshi AS, Castillo MB, Koike TE, Roy A, Gunaratne PH, Kumar A
published in: Life science alliance
information resource reference: Fn14 promotes myoblast fusion during regenerative myogenesis. Life Sci Alliance. 2023 12; 6(12).
journal title abbreviation: Life Sci Alliance
publication date: 2023-10-09T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

H19X-encoded miR-322(424)/miR-503 regulates muscle mass by targeting translation initiation factors.
PubMed Identifier: 34704401
author list: Liang R, Shen X, Wang F, Wang X, DesJarlais A, Syed A, Saba R, Tan Z, Yu F, Ji X, Shrestha S, Ren Y, Yang J, Park Y, Schwartz RJ, Soibam B, McConnell BK, Stewart MD, Kumar A, Liu Y
published in: Journal of cachexia, sarcopenia and muscle
information resource reference: H19X-encoded miR-322(424)/miR-503 regulates muscle mass by targeting translation initiation factors. J Cachexia Sarcopenia Muscle. 2021 12; 12(6):2174-2186.
journal title abbreviation: J Cachexia Sarcopenia Muscle
publication date: 2021-10-26T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Tunneling nanotube-like structures regulate distant cellular interactions during heart formation.
PubMed Identifier: 40080583
author list: Miao L, Lu Y, Nusrat A, Fan G, Zhang S, Zhao L, Wu CL, Guo H, Huyen TLN, Zheng Y, Fan ZC, Shou W, Schwartz RJ, Liu Y, Kumar A, Sui H, Serysheva II, Burns AR, Wan LQ, Zhou B, Evans SM, Wu M
published in: Science (New York, N.Y.)
information resource reference: Tunneling nanotube-like structures regulate distant cellular interactions during heart formation. Science. 2025 Mar 14; 387(6739):eadd3417.
journal title abbreviation: Science
publication date: 2025-03-14T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Muscle Development
MeSH DescriptorUI: D024510
MeSH semantic group name: Physiology
number of authors: 6
number of publications: 13
uniqueness weight: 0.980952
type: Concept

University of Houston
type: Organization

Authorship 8771
type: Authorship
author rank in publication: 15
linked author: Kumar, Ashok
linked information resource: Tunneling nanotube-like structures regulate distant cellular interactions during heart formation.

Authorship 8772
type: Authorship
author rank in publication: 5
linked author: Kumar, Ashok
linked information resource: https://profilesrns.times.uh.edu/profile/344301

Authorship 8773
type: Authorship
author rank in publication: 3
linked author: Kumar, Ashok
linked information resource: Fibroblast growth factor-inducible 14 regulates satellite cell self-renewal and expansion during skeletal muscle repair.

Authorship 8774
type: Authorship
author rank in publication: 3
linked author: Kumar, Ashok
linked information resource: Fibroblast growth factor-inducible 14 regulates satellite cell self-renewal and expansion during skeletal muscle repair.

Authorship 8775
type: Authorship
author rank in publication: 8
linked author: Kumar, Ashok
linked information resource: Single-nucleus transcriptomic analysis reveals the regulatory circuitry of myofiber XBP1 during regenerative myogenesis.

Authorship 8776
type: Authorship
author rank in publication: 10
linked author: Kumar, Ashok
linked information resource: The IRE1a/XBP1 signaling axis drives myoblast fusion in adult skeletal muscle.

Authorship 8777
type: Authorship
author rank in publication: 12
linked author: Kumar, Ashok
linked information resource: ?1 integrins regulate cellular behaviour and cardiomyocyte organization during ventricular wall formation.

Authorship 8778
type: Authorship
author rank in publication: 6
linked author: Kumar, Ashok
linked information resource: Mechanisms of gelofusine protection in an in vitro model of polymyxin B-associated renal injury.

Authorship 8779
type: Authorship
author rank in publication: 7
linked author: Kumar, Ashok
linked information resource: Unconventional Activation of IRE1 Enhances Th17 Responses and Promotes Airway Neutrophilia.

Authorship 8780
type: Authorship
author rank in publication: 3
linked author: Kumar, Ashok
linked information resource: ER stress and ERO1: Potential therapeutic targets for inherited myopathies.

Authorship 8781
type: Authorship
author rank in publication: 7
linked author: Kumar, Ashok
linked information resource: Fn14 promotes myoblast fusion during regenerative myogenesis.

Authorship 8782
type: Authorship
author rank in publication: 4
linked author: Kumar, Ashok
linked information resource: Estrogen-Related Receptor Gamma Gene Therapy Promotes Therapeutic Angiogenesis and Muscle Recovery in Preclinical Model of PAD.

Authorship 8783
type: Authorship
author rank in publication: 7
linked author: Kumar, Ashok
linked information resource: Unconventional Activation of IRE1 Enhances TH17 Responses and Promotes Neutrophilic Airway Inflammation.

Authorship 8784
type: Authorship
author rank in publication: 3
linked author: Kumar, Ashok
linked information resource: Emerging role of TAK1 in the regulation of skeletal muscle mass.

Authorship 8785
type: Authorship
author rank in publication: 12
linked author: Kumar, Ashok
linked information resource: Innately expressed estrogen-related receptors in the skeletal muscle are indispensable for exercise fitness.

Authorship 8786
type: Authorship
author rank in publication: 8
linked author: Kumar, Ashok
linked information resource: Targeted ablation of Fn14 receptor improves exercise capacity and inhibits neurogenic muscle atrophy.

Authorship 8787
type: Authorship
author rank in publication: 8
linked author: Kumar, Ashok
linked information resource: The fibrotic niche impairs satellite cell function and muscle regeneration in mouse models of Marfan syndrome.

Authorship 8788
type: Authorship
author rank in publication: 5
linked author: Kumar, Ashok
linked information resource: Estrogen-related receptor alpha is an AMPK-regulated factor that promotes ischemic muscle revascularization and recovery in diet-induced obese mice.

Authorship 8789
type: Authorship
author rank in publication: 1
linked author: Kumar, Ashok
linked information resource: Nuclear receptors as potential therapeutic targets in peripheral arterial disease and related myopathy.

Authorship 8790
type: Authorship
author rank in publication: 2
linked author: Kumar, Ashok
linked information resource: Supraphysiological activation of TAK1 promotes skeletal muscle growth and mitigates neurogenic atrophy.

Authorship 8791
type: Authorship
author rank in publication: 6
linked author: Kumar, Ashok
linked information resource: The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism.

Authorship 8792
type: Authorship
author rank in publication: 19
linked author: Kumar, Ashok
linked information resource: H19X-encoded miR-322(424)/miR-503 regulates muscle mass by targeting translation initiation factors.

Authorship 8793
type: Authorship
author rank in publication: 7
linked author: Kumar, Ashok
linked information resource: MyD88-mediated signaling intercedes in neurogenic muscle atrophy through multiple mechanisms.

Authorship 8794
type: Authorship
author rank in publication: 1273
linked author: Kumar, Ashok
linked information resource: Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.

Authorship 8795
type: Authorship
author rank in publication: 4
linked author: Kumar, Ashok
linked information resource: Therapeutic Targeting of PTEN in Duchenne Muscular Dystrophy.

Authorship 8796
type: Authorship
author rank in publication: 5
linked author: Kumar, Ashok
linked information resource: TAK1 preserves skeletal muscle mass and mitochondrial function through redox homeostasis.

Authorship 8797
type: Authorship
author rank in publication: 2
linked author: Kumar, Ashok
linked information resource: ER Stress and Unfolded Protein Response in Cancer Cachexia.

Authorship 8798
type: Authorship
author rank in publication: 1096
linked author: Kumar, Ashok
linked information resource: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Authorship 8799
type: Authorship
author rank in publication: 4
linked author: Kumar, Ashok
linked information resource: Metal chelate affinity precipitation of RNA and purification of plasmid DNA.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
PubMed Identifier: 26799652
author list: Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Alg?l H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, B?nhegyi G, Bao H, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolom? A, Bassham DC, Bassi MT, Bast RC, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR, Becker C, Beckham JD, B?dard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, B?nard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, B?ckler S, Boes M, Boesze-Battaglia …
published in: Autophagy
information resource reference: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016; 12(1):1-222.
journal title abbreviation: Autophagy
publication date: 2016-01-01T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
PubMed Identifier: 33634751
author list: Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-Gómez E, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almacellas E, Almasan A, Alonso A, Alonso GD, Altan-Bonnet N, Altieri DC, Álvarez ÉMC, Alves S, Alves da Costa C, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andrade-Silva M, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antas P, Antebi A, Antón Z, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Araújo WL, Araya J, Arden C, Arévalo MA, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Arnauné-Pelloquin L, Aroca A, Arroyo DS, Arsov I, Artero R, Asaro DML, Aschner M, Ashrafizadeh M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R, Avagliano L, Ávalos Y, Aveic S, Aveleira CA, Avin-Wittenberg T, Aydin Y, Ayton S, Ayyadevara S, Azzopardi M, Baba M, Backer JM, Backues SK, Bae DH, Bae ON, Bae SH, Baehrecke EH, Baek A, Baek SH, Baek SH, Bagetta G, Bagniewska-Zadworna A, Bai H, Bai J, Bai X, Bai Y, Bairagi N, Baksi S, Balbi T, Baldari CT, Balduini W, Ballabio A, Ballester M, Balazadeh S, Balzan R, Bandopadhyay R, Banerjee S, Banerjee S, Bánréti Á, Bao Y, Baptista MS, Baracca A, Barbati C, Bargiela A, Barilà D, Barlow PG, Barmada SJ, Barreiro E, Barreto GE, Bartek J, Bartel B, Bartolome A, Barve GR, Basagoudanavar SH, Bassham DC, Bast RC, Basu A, Batoko H, Batten I, Baulieu EE, Baumgarner BL, Bayry J, Beale R, Beau I, Beaumatin F, Bechara LRG, Beck GR, Beers MF, Begun J, Behrends C, Behrens GMN, Bei R, Bejarano E, Bel S, B…
published in: Autophagy
information resource reference: Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy. 2021 Jan; 17(1):1-382.
journal title abbreviation: Autophagy
publication date: 2021-02-08T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Mechanisms of gelofusine protection in an in vitro model of polymyxin B-associated renal injury.
PubMed Identifier: 38779756
author list: Hudson CS, Roy A, Li Q, Joshi AS, Yin T, Kumar A, Sheikh-Hamad D, Tam VH
published in: American journal of physiology. Renal physiology
information resource reference: Mechanisms of gelofusine protection in an in vitro model of polymyxin B-associated renal injury. Am J Physiol Renal Physiol. 2024 Jul 01; 327(1):F137-F145.
journal title abbreviation: Am J Physiol Renal Physiol
publication date: 2024-05-23T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

https://profilesrns.times.uh.edu/profile/344301
PubMed Identifier: 39982073
author list: McPherson JK, Hurdle JG, Baker ML, Hussain T, Kumar A, Garey KW
published in: Antimicrobial agents and chemotherapy
information resource reference: The microbiome-restorative potential of ibezapolstat for the treatment of Clostridioides difficile infection is predicted through variant PolC-type DNA polymerase III in Lachnospiraceae and Oscillospiraceae. Antimicrob Agents Chemother. 2025 Feb 21; e0167924.
journal title abbreviation: Antimicrob Agents Chemother
publication date: 2025-02-21T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource
label: The microbiome-restorative potential of ibezapolstat for the treatment of Clostridioides difficile infection is predicted through variant PolC-type DNA polymerase III in Lachnospiraceae and Oscillospiraceae.

Fibroblast growth factor-inducible 14 regulates satellite cell self-renewal and expansion during skeletal muscle repair.
PubMed Identifier: 39874107
author list: Tomaz da Silva M, Joshi AS, Kumar A
published in: JCI insight
information resource reference: Fibroblast growth factor-inducible 14 regulates satellite cell self-renewal and expansion during skeletal muscle repair. JCI Insight. 2025 Jan 28; 10(5).
journal title abbreviation: JCI Insight
publication date: 2025-01-28T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Fibroblast growth factor-inducible 14 regulates satellite cell self-renewal and expansion during skeletal muscle repair.
PubMed Identifier: 39803454
author list: Tomaz da Silva M, Joshi AS, Kumar A
published in: bioRxiv : the preprint server for biology
information resource reference: Fibroblast growth factor-inducible 14 regulates satellite cell self-renewal and expansion during skeletal muscle repair. bioRxiv. 2025 Jan 02.
journal title abbreviation: bioRxiv
publication date: 2025-01-02T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Unconventional Activation of IRE1 Enhances Th17 Responses and Promotes Airway Neutrophilia.
PubMed Identifier: 38593442
author list: Wu D, Zhang X, Zimmerly KM, Wang R, Livingston A, Iwawaki T, Kumar A, Wu X, Campen M, Mandell MA, Liu M, Yang XO
published in: American journal of respiratory cell and molecular biology
information resource reference: Unconventional Activation of IRE1 Enhances Th17 Responses and Promotes Airway Neutrophilia. Am J Respir Cell Mol Biol. 2024 Aug; 71(2):169-181.
journal title abbreviation: Am J Respir Cell Mol Biol
publication date: 2024-08-01T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

ER stress and ERO1: Potential therapeutic targets for inherited myopathies.
PubMed Identifier: 38508147
author list: Roy A, Joshi AS, Kumar A
published in: Cell reports. Medicine
information resource reference: ER stress and ERO1: Potential therapeutic targets for inherited myopathies. Cell Rep Med. 2024 Mar 19; 5(3):101462.
journal title abbreviation: Cell Rep Med
publication date: 2024-03-19T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Estrogen-Related Receptor Gamma Gene Therapy Promotes Therapeutic Angiogenesis and Muscle Recovery in Preclinical Model of PAD.
PubMed Identifier: 37548153
author list: Sopariwala DH, Rios AS, Saley A, Kumar A, Narkar VA
published in: Journal of the American Heart Association
information resource reference: Estrogen-Related Receptor Gamma Gene Therapy Promotes Therapeutic Angiogenesis and Muscle Recovery in Preclinical Model of PAD. J Am Heart Assoc. 2023 Aug 15; 12(16):e028880.
journal title abbreviation: J Am Heart Assoc
publication date: 2023-08-07T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Unconventional Activation of IRE1 Enhances TH17 Responses and Promotes Neutrophilic Airway Inflammation.
PubMed Identifier: 37461622
author list: Wu D, Zhang X, Zimmerly KM, Wang R, Livingston A, Iwawaki T, Kumar A, Wu X, Mandell MA, Liu M, Yang XO
published in: bioRxiv : the preprint server for biology
information resource reference: Unconventional Activation of IRE1 Enhances TH17 Responses and Promotes Neutrophilic Airway Inflammation. bioRxiv. 2023 Jul 08.
journal title abbreviation: bioRxiv
publication date: 2023-07-08T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Emerging role of TAK1 in the regulation of skeletal muscle mass.
PubMed Identifier: 36789559
author list: Roy A, Narkar VA, Kumar A
published in: BioEssays : news and reviews in molecular, cellular and developmental biology
information resource reference: Emerging role of TAK1 in the regulation of skeletal muscle mass. Bioessays. 2023 04; 45(4):e2300003.
journal title abbreviation: Bioessays
publication date: 2023-02-15T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Innately expressed estrogen-related receptors in the skeletal muscle are indispensable for exercise fitness.
PubMed Identifier: 36583689
author list: Sopariwala DH, Rios AS, Pei G, Roy A, Tomaz da Silva M, Thi Thu Nguyen H, Saley A, Van Drunen R, Kralli A, Mahan K, Zhao Z, Kumar A, Narkar VA
published in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology
information resource reference: Innately expressed estrogen-related receptors in the skeletal muscle are indispensable for exercise fitness. FASEB J. 2023 02; 37(2):e22727.
journal title abbreviation: FASEB J
publication date: 2023-02-01T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Targeted ablation of Fn14 receptor improves exercise capacity and inhibits neurogenic muscle atrophy.
PubMed Identifier: 36412933
author list: Tomaz da Silva M, Joshi AS, Koike TE, Roy A, Mathukumalli K, Sopariwala DH, Narkar VA, Kumar A
published in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology
information resource reference: Targeted ablation of Fn14 receptor improves exercise capacity and inhibits neurogenic muscle atrophy. FASEB J. 2022 12; 36(12):e22666.
journal title abbreviation: FASEB J
publication date: 2022-12-01T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

The fibrotic niche impairs satellite cell function and muscle regeneration in mouse models of Marfan syndrome.
PubMed Identifier: 36164969
author list: Tomaz da Silva M, Santos AR, Koike TE, Nascimento TL, Rozanski A, Bosnakovski D, Pereira LV, Kumar A, Kyba M, Miyabara EH
published in: Acta physiologica (Oxford, England)
information resource reference: The fibrotic niche impairs satellite cell function and muscle regeneration in mouse models of Marfan syndrome. Acta Physiol (Oxf). 2023 Jan; 237(1):e13889.
journal title abbreviation: Acta Physiol (Oxf)
publication date: 2022-10-17T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Estrogen-related receptor alpha is an AMPK-regulated factor that promotes ischemic muscle revascularization and recovery in diet-induced obese mice.
PubMed Identifier: 36089981
author list: Sopariwala DH, Rios AS, Park MK, Song MS, Kumar A, Narkar VA
published in: FASEB bioAdvances
information resource reference: Estrogen-related receptor alpha is an AMPK-regulated factor that promotes ischemic muscle revascularization and recovery in diet-induced obese mice. FASEB Bioadv. 2022 Sep; 4(9):602-618.
journal title abbreviation: FASEB Bioadv
publication date: 2022-06-22T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Nuclear receptors as potential therapeutic targets in peripheral arterial disease and related myopathy.
PubMed Identifier: 35942640
author list: Kumar A, Narkar VA
published in: The FEBS journal
information resource reference: Nuclear receptors as potential therapeutic targets in peripheral arterial disease and related myopathy. FEBS J. 2023 10; 290(19):4596-4613.
journal title abbreviation: FEBS J
publication date: 2022-08-18T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Supraphysiological activation of TAK1 promotes skeletal muscle growth and mitigates neurogenic atrophy.
PubMed Identifier: 35459245
author list: Roy A, Kumar A
published in: Nature communications
information resource reference: Supraphysiological activation of TAK1 promotes skeletal muscle growth and mitigates neurogenic atrophy. Nat Commun. 2022 04 22; 13(1):2201.
journal title abbreviation: Nat Commun
publication date: 2022-04-22T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism.
PubMed Identifier: 34812145
author list: Roy A, Tomaz da Silva M, Bhat R, Bohnert KR, Iwawaki T, Kumar A
published in: eLife
information resource reference: The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism. Elife. 2021 11 23; 10.
journal title abbreviation: Elife
publication date: 2021-11-23T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

MyD88-mediated signaling intercedes in neurogenic muscle atrophy through multiple mechanisms.
PubMed Identifier: 34325487
author list: Parveen A, Bohnert KR, Tomaz da Silva M, Wen Y, Bhat R, Roy A, Kumar A
published in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology
information resource reference: MyD88-mediated signaling intercedes in neurogenic muscle atrophy through multiple mechanisms. FASEB J. 2021 08; 35(8):e21821.
journal title abbreviation: FASEB J
publication date: 2021-08-01T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Therapeutic Targeting of PTEN in Duchenne Muscular Dystrophy.
PubMed Identifier: 33338398
author list: Parveen A, Wen Y, Roy A, Kumar A
published in: Molecular therapy : the journal of the American Society of Gene Therapy
information resource reference: Therapeutic Targeting of PTEN in Duchenne Muscular Dystrophy. Mol Ther. 2021 01 06; 29(1):8-9.
journal title abbreviation: Mol Ther
publication date: 2020-12-17T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

TAK1 preserves skeletal muscle mass and mitochondrial function through redox homeostasis.
PubMed Identifier: 32923988
author list: Roy A, Sharma AK, Nellore K, Narkar VA, Kumar A
published in: FASEB bioAdvances
information resource reference: TAK1 preserves skeletal muscle mass and mitochondrial function through redox homeostasis. FASEB Bioadv. 2020 Sep; 2(9):538-553.
journal title abbreviation: FASEB Bioadv
publication date: 2020-08-07T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

ER Stress and Unfolded Protein Response in Cancer Cachexia.
PubMed Identifier: 31817027
author list: Roy A, Kumar A
published in: Cancers
information resource reference: ER Stress and Unfolded Protein Response in Cancer Cachexia. Cancers (Basel). 2019 Dec 03; 11(12).
journal title abbreviation: Cancers (Basel)
publication date: 2019-12-03T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Role of TWEAK in skeletal muscle metabolism
end date: 2018-05-31
grant awarded by: NIH
principal investigator name: KUMAR, ASHOK
start date: 2007-02-01
type: Agreement
type: Grant
sponsor award id: R01AG029623

MYD88 Signaling in Mammalian Myoblast Fusion
end date: 2021-08-31
grant awarded by: NIH
principal investigator name: KUMAR, ASHOK
start date: 2015-09-14
type: Agreement
type: Grant
sponsor award id: R01AR068313

TAK1 signaling in skeletal muscle
end date: 2022-06-30
grant awarded by: NIH
principal investigator name: KUMAR, ASHOK
start date: 2011-07-01
type: Agreement
type: Grant
sponsor award id: R01AR059810

TWEAK/Fn14/UPR Signaling in Skeletal Muscle Wasting
end date: 2028-01-31
grant awarded by: NIH
principal investigator name: KUMAR, ASHOK
start date: 2023-04-01
type: Agreement
type: Grant
sponsor award id: R01AR081487

TAK1 signaling in Rhabdomyosarcoma tumorigenesis and growth
end date: 2030-01-31
grant awarded by: NIH
principal investigator name: KUMAR, ASHOK
start date: 2025-02-01
type: Agreement
type: Grant
sponsor award id: R01CA294365

Principal Investigator
type: Researcher Role
type: Role
researcher role of: Kumar, Ashok
contributes to: MYD88 Signaling in Mammalian Myoblast Fusion

Principal Investigator
type: Researcher Role
type: Role
researcher role of: Kumar, Ashok
contributes to: TWEAK/Fn14/UPR Signaling in Skeletal Muscle Wasting

Principal Investigator
type: Researcher Role
type: Role
researcher role of: Kumar, Ashok
contributes to: Role of TWEAK in skeletal muscle metabolism

Principal Investigator
type: Researcher Role
type: Role
researcher role of: Kumar, Ashok
contributes to: TAK1 signaling in skeletal muscle

Principal Investigator
type: Researcher Role
type: Role
researcher role of: Kumar, Ashok
contributes to: TAK1 signaling in Rhabdomyosarcoma tumorigenesis and growth

Professor
is primary position: true
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HR job title: Professor
position in organization: Arizona State University (ASU)

Associate Professor
is primary position: true
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position in organization: University of Houston

Associate Professor
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position in organization: University of Houston

Professor
is primary position: true
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position in organization: University of Houston

Associate Professor
is primary position: true
position in department: Pharmacological and Pharmaceutical Sciences
position in division: College of Pharmacy
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position in organization: University of Houston

Professor
is primary position: true
position in department: Pharmacological and Pharmaceutical Sciences
position in division: College of Pharmacy
sort order: 1
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HR job title: Professor
position in organization: University of Houston

Associate Professor
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position in department: Pharmacological and Pharmaceutical Sciences
position in division: College of Pharmacy
sort order: 1
type: Position
HR job title: Associate Professor
position in organization: University of Houston

Associate Professor
is primary position: true
position in department: Pharmacological and Pharmaceutical Sciences
position in division: College of Pharmacy
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HR job title: Associate Professor
position in organization: University of Houston

Assistant Professor
is primary position: true
position in department: Pharmacological and Pharmaceutical Sciences
position in division: College of Pharmacy
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HR job title: Assistant Professor
position in organization: University of Houston