Pharmacological and Pharmaceutical Sciences
Balan S, Murphy J, Galaev I, Kumar A, Fox GE, Mattiasson B, Willson RC
Metal chelate affinity precipitation of RNA and purification of plasmid DNA. Biotechnol Lett. 2003 Jul; 25(13):1111-6.
Metal chelate affinity precipitation of RNA and purification of plasmid DNA.
Joshi AS, Castillo MB, Tomaz da Silva M, Vuong AT, Gunaratne PH, Darabi R, Liu Y, Kumar A
Single-nucleus transcriptomic analysis reveals the regulatory circuitry of myofiber XBP1 during regenerative myogenesis. iScience. 2024 Dec 20; 27(12):111372.
Single-nucleus transcriptomic analysis reveals the regulatory circuitry of myofiber XBP1 during regenerative myogenesis.
Joshi AS, Tomaz da Silva M, Roy A, Koike TE, Wu M, Castillo MB, Gunaratne PH, Liu Y, Iwawaki T, Kumar A
The IRE1a/XBP1 signaling axis drives myoblast fusion in adult skeletal muscle. EMBO Rep. 2024 Aug; 25(8):3627-3650.
The IRE1a/XBP1 signaling axis drives myoblast fusion in adult skeletal muscle.
Miao L, Lu Y, Nusrat A, Zhao L, Castillo M, Xiao Y, Guo H, Liu Y, Gunaratne P, Schwartz RJ, Burns AR, Kumar A, DiPersio CM, Wu M
?1 integrins regulate cellular behaviour and cardiomyocyte organization during ventricular wall formation. Cardiovasc Res. 2024 Sep 21; 120(11):1279-1294.
?1 integrins regulate cellular behaviour and cardiomyocyte organization during ventricular wall formation.
Tomaz da Silva M, Joshi AS, Castillo MB, Koike TE, Roy A, Gunaratne PH, Kumar A
Fn14 promotes myoblast fusion during regenerative myogenesis. Life Sci Alliance. 2023 12; 6(12).
Fn14 promotes myoblast fusion during regenerative myogenesis.
Liang R, Shen X, Wang F, Wang X, DesJarlais A, Syed A, Saba R, Tan Z, Yu F, Ji X, Shrestha S, Ren Y, Yang J, Park Y, Schwartz RJ, Soibam B, McConnell BK, Stewart MD, Kumar A, Liu Y
Journal of cachexia, sarcopenia and muscle
H19X-encoded miR-322(424)/miR-503 regulates muscle mass by targeting translation initiation factors. J Cachexia Sarcopenia Muscle. 2021 12; 12(6):2174-2186.
H19X-encoded miR-322(424)/miR-503 regulates muscle mass by targeting translation initiation factors.
Miao L, Lu Y, Nusrat A, Fan G, Zhang S, Zhao L, Wu CL, Guo H, Huyen TLN, Zheng Y, Fan ZC, Shou W, Schwartz RJ, Liu Y, Kumar A, Sui H, Serysheva II, Burns AR, Wan LQ, Zhou B, Evans SM, Wu M
Tunneling nanotube-like structures regulate distant cellular interactions during heart formation. Science. 2025 Mar 14; 387(6739):eadd3417.
Tunneling nanotube-like structures regulate distant cellular interactions during heart formation.
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016; 12(1):1-222.
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-Gómez E, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almacellas E, Almasan A, Alonso A, Alonso GD, Altan-Bonnet N, Altieri DC, Álvarez ÉMC, Alves S, Alves da Costa C, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andrade-Silva M, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antas P, Antebi A, Antón Z, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Araújo WL, Araya J, Arden C, Arévalo MA, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Arnauné-Pelloquin L, Aroca A, Arroyo DS, Arsov I, Artero R, Asaro DML, Aschner M, Ashrafizadeh M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R, Avagliano L, Ávalos Y, Aveic S, Aveleira CA, Avin-Wittenberg T, Aydin Y, Ayton S, Ayyadevara S, Azzopardi M, Baba M, Backer JM, Backues SK, Bae DH, Bae ON, Bae SH, Baehrecke EH, Baek A, Baek SH, Baek SH, Bagetta G, Bagniewska-Zadworna A, Bai H, Bai J, Bai X, Bai Y, Bairagi N, Baksi S, Balbi T, Baldari CT, Balduini W, Ballabio A, Ballester M, Balazadeh S, Balzan R, Bandopadhyay R, Banerjee S, Banerjee S, Bánréti Á, Bao Y, Baptista MS, Baracca A, Barbati C, Bargiela A, Barilà D, Barlow PG, Barmada SJ, Barreiro E, Barreto GE, Bartek J, Bartel B, Bartolome A, Barve GR, Basagoudanavar SH, Bassham DC, Bast RC, Basu A, Batoko H, Batten I, Baulieu EE, Baumgarner BL, Bayry J, Beale R, Beau I, Beaumatin F, Bechara LRG, Beck GR, Beers MF, Begun J, Behrends C, Behrens GMN, Bei R, Bejarano E, Bel S, Behl C, Belaid A, Belgareh-Touzé N, Bellarosa C, Belleudi F, Belló Pérez M, Bello-Morales R, Beltran JSO, Beltran S, Benbrook DM, Bendorius M, Benitez BA, Benito-Cuesta I, Bensalem J, Berchtold MW, Berezowska S, Bergamaschi D, Bergami M, Bergmann A, Berliocchi L, Berlioz-Torrent C, Bernard A, Berthoux L, Besirli CG, Besteiro S, Betin VM, Beyaert R, Bezbradica JS, Bhaskar K, Bhatia-Kissova I, Bhattacharya R, Bhattacharya S, Bhattacharyya S, Bhuiyan MS, Bhutia SK, Bi L, Bi X, Biden TJ, Bijian K, Billes VA, Binart N, Bincoletto C, Birgisdottir AB, Bjorkoy G, Blanco G, Blas-Garcia A, Blasiak J, Blomgran R, Blomgren K, Blum JS, Boada-Romero E, Boban M, Boesze-Battaglia K, Boeuf P, Boland B, Bomont P, Bonaldo P, Bonam SR, Bonfili L, Bonifacino JS, Boone BA, Bootman MD, Bordi M, Borner C, Bornhauser BC, Borthakur G, Bosch J, Bose S, Botana LM, Botas J, Boulanger CM, Boulton ME, Bourdenx M, Bourgeois B, Bourke NM, Bousquet G, Boya P, Bozhkov PV, Bozi LHM, Bozkurt TO, Brackney DE, Brandts CH, Braun RJ, Braus GH, Bravo-Sagua R, Bravo-San Pedro JM, Brest P, Bringer MA, Briones-Herrera A, Broaddus VC, Brodersen P, Brodsky JL, Brody SL, Bronson PG, Bronstein JM, Brown CN, Brown RE, Brum PC, Brumell JH, Brunetti-Pierri N, Bruno D, Bryson-Richardson RJ, Bucci C, Buchrieser C, Bueno M, Buitrago-Molina LE, Buraschi S, Buch S, Buchan JR, Buckingham EM, Budak H, Budini M, Bultynck G, Burada F, Burgoyne JR, Burón MI, Bustos V, Büttner S, Butturini E, Byrd A, Cabas I, Cabrera-Benitez S, Cadwell K, Cai J, Cai L, Cai Q, Cairó M, Calbet JA, Caldwell GA, Caldwell KA, Call JA, Calvani R, Calvo AC, Calvo-Rubio Barrera M, Camara NO, Camonis JH, Camougrand N, Campanella M, Campbell EM, Campbell-Valois FX, Campello S, Campesi I, Campos JC, Camuzard O, Cancino J, Candido de Almeida D, Canesi L, Caniggia I, Canonico B, Cantí C, Cao B, Caraglia M, Caramés B, Carchman EH, Cardenal-Muñoz E, Cardenas C, Cardenas L, Cardoso SM, Carew JS, Carle GF, Carleton G, Carloni S, Carmona-Gutierrez D, et al
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy. 2021 Jan; 17(1):1-382.
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
Hudson CS, Roy A, Li Q, Joshi AS, Yin T, Kumar A, Sheikh-Hamad D, Tam VH
American journal of physiology. Renal physiology
Mechanisms of gelofusine protection in an in vitro model of polymyxin B-associated renal injury. Am J Physiol Renal Physiol. 2024 Jul 01; 327(1):F137-F145.
Mechanisms of gelofusine protection in an in vitro model of polymyxin B-associated renal injury.
McPherson JK, Hurdle JG, Baker ML, Hussain T, Kumar A, Garey KW
The microbiome-restorative potential of ibezapolstat for the treatment of Clostridioides difficile infection is predicted through variant PolC-type DNA polymerase III in Lachnospiraceae and Oscillospiraceae. Antimicrob Agents Chemother. 2025 Feb 21; e0167924.
The microbiome-restorative potential of ibezapolstat for the treatment of Clostridioides difficile infection is predicted through variant PolC-type DNA polymerase III in Lachnospiraceae and Oscillospiraceae.
Fibroblast growth factor-inducible 14 regulates satellite cell self-renewal and expansion during skeletal muscle repair. JCI Insight. 2025 Jan 28; 10(5).
Fibroblast growth factor-inducible 14 regulates satellite cell self-renewal and expansion during skeletal muscle repair.
bioRxiv : the preprint server for biology
Fibroblast growth factor-inducible 14 regulates satellite cell self-renewal and expansion during skeletal muscle repair. bioRxiv. 2025 Jan 02.
Wu D, Zhang X, Zimmerly KM, Wang R, Livingston A, Iwawaki T, Kumar A, Wu X, Campen M, Mandell MA, Liu M, Yang XO
American journal of respiratory cell and molecular biology
Unconventional Activation of IRE1 Enhances Th17 Responses and Promotes Airway Neutrophilia. Am J Respir Cell Mol Biol. 2024 Aug; 71(2):169-181.
Unconventional Activation of IRE1 Enhances Th17 Responses and Promotes Airway Neutrophilia.
ER stress and ERO1: Potential therapeutic targets for inherited myopathies. Cell Rep Med. 2024 Mar 19; 5(3):101462.
ER stress and ERO1: Potential therapeutic targets for inherited myopathies.
Sopariwala DH, Rios AS, Saley A, Kumar A, Narkar VA
Journal of the American Heart Association
Estrogen-Related Receptor Gamma Gene Therapy Promotes Therapeutic Angiogenesis and Muscle Recovery in Preclinical Model of PAD. J Am Heart Assoc. 2023 Aug 15; 12(16):e028880.
Estrogen-Related Receptor Gamma Gene Therapy Promotes Therapeutic Angiogenesis and Muscle Recovery in Preclinical Model of PAD.
Wu D, Zhang X, Zimmerly KM, Wang R, Livingston A, Iwawaki T, Kumar A, Wu X, Mandell MA, Liu M, Yang XO
Unconventional Activation of IRE1 Enhances TH17 Responses and Promotes Neutrophilic Airway Inflammation. bioRxiv. 2023 Jul 08.
Unconventional Activation of IRE1 Enhances TH17 Responses and Promotes Neutrophilic Airway Inflammation.
BioEssays : news and reviews in molecular, cellular and developmental biology
Emerging role of TAK1 in the regulation of skeletal muscle mass. Bioessays. 2023 04; 45(4):e2300003.
Emerging role of TAK1 in the regulation of skeletal muscle mass.
Sopariwala DH, Rios AS, Pei G, Roy A, Tomaz da Silva M, Thi Thu Nguyen H, Saley A, Van Drunen R, Kralli A, Mahan K, Zhao Z, Kumar A, Narkar VA
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Innately expressed estrogen-related receptors in the skeletal muscle are indispensable for exercise fitness. FASEB J. 2023 02; 37(2):e22727.
Innately expressed estrogen-related receptors in the skeletal muscle are indispensable for exercise fitness.
Tomaz da Silva M, Joshi AS, Koike TE, Roy A, Mathukumalli K, Sopariwala DH, Narkar VA, Kumar A
Targeted ablation of Fn14 receptor improves exercise capacity and inhibits neurogenic muscle atrophy. FASEB J. 2022 12; 36(12):e22666.
Targeted ablation of Fn14 receptor improves exercise capacity and inhibits neurogenic muscle atrophy.
Tomaz da Silva M, Santos AR, Koike TE, Nascimento TL, Rozanski A, Bosnakovski D, Pereira LV, Kumar A, Kyba M, Miyabara EH
The fibrotic niche impairs satellite cell function and muscle regeneration in mouse models of Marfan syndrome. Acta Physiol (Oxf). 2023 Jan; 237(1):e13889.
The fibrotic niche impairs satellite cell function and muscle regeneration in mouse models of Marfan syndrome.
Sopariwala DH, Rios AS, Park MK, Song MS, Kumar A, Narkar VA
Estrogen-related receptor alpha is an AMPK-regulated factor that promotes ischemic muscle revascularization and recovery in diet-induced obese mice. FASEB Bioadv. 2022 Sep; 4(9):602-618.
Estrogen-related receptor alpha is an AMPK-regulated factor that promotes ischemic muscle revascularization and recovery in diet-induced obese mice.
Nuclear receptors as potential therapeutic targets in peripheral arterial disease and related myopathy. FEBS J. 2023 10; 290(19):4596-4613.
Nuclear receptors as potential therapeutic targets in peripheral arterial disease and related myopathy.
Supraphysiological activation of TAK1 promotes skeletal muscle growth and mitigates neurogenic atrophy. Nat Commun. 2022 04 22; 13(1):2201.
Supraphysiological activation of TAK1 promotes skeletal muscle growth and mitigates neurogenic atrophy.
Roy A, Tomaz da Silva M, Bhat R, Bohnert KR, Iwawaki T, Kumar A
The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism. Elife. 2021 11 23; 10.
The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism.
Parveen A, Bohnert KR, Tomaz da Silva M, Wen Y, Bhat R, Roy A, Kumar A
MyD88-mediated signaling intercedes in neurogenic muscle atrophy through multiple mechanisms. FASEB J. 2021 08; 35(8):e21821.
MyD88-mediated signaling intercedes in neurogenic muscle atrophy through multiple mechanisms.
Molecular therapy : the journal of the American Society of Gene Therapy
Therapeutic Targeting of PTEN in Duchenne Muscular Dystrophy. Mol Ther. 2021 01 06; 29(1):8-9.
Therapeutic Targeting of PTEN in Duchenne Muscular Dystrophy.
Roy A, Sharma AK, Nellore K, Narkar VA, Kumar A
TAK1 preserves skeletal muscle mass and mitochondrial function through redox homeostasis. FASEB Bioadv. 2020 Sep; 2(9):538-553.
TAK1 preserves skeletal muscle mass and mitochondrial function through redox homeostasis.
ER Stress and Unfolded Protein Response in Cancer Cachexia. Cancers (Basel). 2019 Dec 03; 11(12).
ER Stress and Unfolded Protein Response in Cancer Cachexia.
Role of TWEAK in skeletal muscle metabolism
MYD88 Signaling in Mammalian Myoblast Fusion
TWEAK/Fn14/UPR Signaling in Skeletal Muscle Wasting
TAK1 signaling in Rhabdomyosarcoma tumorigenesis and growth