Pharmacological and Pharmaceutical Sciences
Liver X receptor ?: new player in the regulatory network of thyroid hormone and 'browning' of white fat. Adipocyte. 2016 Apr-Jun; 5(2):238-42.
Liver X receptor ?: new player in the regulatory network of thyroid hormone and 'browning' of white fat.
Wang D, Tang M, Zhang P, Yang K, Huang L, Wu M, Shen Q, Yue J, Wang W, Gong Y, Warner M, Dai L, He H, Yang Z, Gustafsson JA, Zhou S
Proceedings of the National Academy of Sciences of the United States of America
Activation of ER? hijacks the splicing machinery to trigger R-loop formation in triple-negative breast cancer. Proc Natl Acad Sci U S A. 2024 Mar 26; 121(13):e2306814121.
Activation of ER? hijacks the splicing machinery to trigger R-loop formation in triple-negative breast cancer.
Song X, Wu W, Dai Y, Warner M, Nalvarte I, Antonson P, Varshney M, Gustafsson J?
International journal of molecular sciences
Loss of ER? in Aging LXRa? Knockout Mice Leads to Colitis. Int J Mol Sci. 2023 Aug 05; 24(15).
Loss of ER? in Aging LXRa? Knockout Mice Leads to Colitis.
Zang Z, Yin H, Du Z, Xie R, Yang L, Cai Y, Wang L, Zhang D, Li X, Liu T, Gong H, Gao J, Yang H, Warner M, Gustafsson JA, Xu H, Fan X
Valproic acid exposure decreases neurogenic potential of outer radial glia in human brain organoids. Front Mol Neurosci. 2022; 15:1023765.
Valproic acid exposure decreases neurogenic potential of outer radial glia in human brain organoids.
Liver X Receptor Regulation of Glial Cell Functions in the CNS. Biomedicines. 2022 Sep 02; 10(9).
Liver X Receptor Regulation of Glial Cell Functions in the CNS.
Song XY, Wu WF, Dai YB, Xu HW, Roman A, Wang L, Warner M, Gustafsson J?
Ablation of Liver X receptor ? in mice leads to overactive macrophages and death of spiral ganglion neurons. Hear Res. 2022 09 01; 422:108534.
Ablation of Liver X receptor ? in mice leads to overactive macrophages and death of spiral ganglion neurons.
Warner M, Fan X, Strom A, Wu W, Gustafsson J?
25 years of ER?: a personal journey. J Mol Endocrinol. 2021 10 15; 68(1):R1-R9.
Wu W, Warner M, Wang L, He WW, Zhao R, Guan X, Botero C, Huang B, Ion C, Coombes C, Gustafsson JA
Drivers and suppressors of triple-negative breast cancer. Proc Natl Acad Sci U S A. 2021 08 17; 118(33).
Drivers and suppressors of triple-negative breast cancer.
Li X, Zhong H, Wang Z, Xiao R, Antonson P, Liu T, Wu C, Zou J, Wang L, Nalvarte I, Xu H, Warner M, Gustafsson JA, Fan X
Loss of liver X receptor ? in astrocytes leads to anxiety-like behaviors via regulating synaptic transmission in the medial prefrontal cortex in mice. Mol Psychiatry. 2021 11; 26(11):6380-6393.
Loss of liver X receptor ? in astrocytes leads to anxiety-like behaviors via regulating synaptic transmission in the medial prefrontal cortex in mice.
Wu WF, Wang L, Spetsieris N, Boukovala M, Efstathiou E, Br?ssner C, Warner M, Gustafsson JA
Estrogen receptor ? and treatment with a phytoestrogen are associated with inhibition of nuclear translocation of EGFR in the prostate. Proc Natl Acad Sci U S A. 2021 03 30; 118(13).
Estrogen receptor ? and treatment with a phytoestrogen are associated with inhibition of nuclear translocation of EGFR in the prostate.
Chaurasiya S, Wu W, Strom AM, Warner M, Gustafsson J?
Estrogen receptor ? regulates AKT activity through up-regulation of INPP4B and inhibits migration of prostate cancer cell line PC-3. Proc Natl Acad Sci U S A. 2020 10 20; 117(42):26347-26355.
Estrogen receptor ? regulates AKT activity through up-regulation of INPP4B and inhibits migration of prostate cancer cell line PC-3.
Warner M, Wu WF, Montanholi L, Nalvarte I, Antonson P, Gustafsson JA
Ventral prostate and mammary gland phenotype in mice with complete deletion of the ER? gene. Proc Natl Acad Sci U S A. 2020 03 03; 117(9):4902-4909.
Ventral prostate and mammary gland phenotype in mice with complete deletion of the ER? gene.
Song XY, Wu WF, Gabbi C, Dai YB, So M, Chaurasiya SP, Wang L, Warner M, Gustafsson J?
Retinal and optic nerve degeneration in liver X receptor ? knockout mice. Proc Natl Acad Sci U S A. 2019 08 13; 116(33):16507-16512.
Retinal and optic nerve degeneration in liver X receptor ? knockout mice.
The Journal of steroid biochemistry and molecular biology
Update on ERbeta. J Steroid Biochem Mol Biol. 2019 07; 191:105312.
Griffiths WJ, Abdel-Khalik J, Yutuc E, Roman G, Warner M, Gustafsson J?, Wang Y
Concentrations of bile acid precursors in cerebrospinal fluid of Alzheimer's disease patients. Free Radic Biol Med. 2019 04; 134:42-52.
Concentrations of bile acid precursors in cerebrospinal fluid of Alzheimer's disease patients.
Zhao L, Huang S, Mei S, Yang Z, Xu L, Zhou N, Yang Q, Shen Q, Wang W, Le X, Lau WB, Lau B, Wang X, Yi T, Zhao X, Wei Y, Warner M, Gustafsson J?, Zhou S
Pharmacological activation of estrogen receptor beta augments innate immunity to suppress cancer metastasis. Proc Natl Acad Sci U S A. 2018 04 17; 115(16):E3673-E3681.
Pharmacological activation of estrogen receptor beta augments innate immunity to suppress cancer metastasis.
Cai Y, Tang X, Chen X, Li X, Wang Y, Bao X, Wang L, Sun D, Zhao J, Xing Y, Warner M, Xu H, Gustafsson J?, Fan X
Liver X receptor ? regulates the development of the dentate gyrus and autistic-like behavior in the mouse. Proc Natl Acad Sci U S A. 2018 03 20; 115(12):E2725-E2733.
Liver X receptor ? regulates the development of the dentate gyrus and autistic-like behavior in the mouse.
Wu WF, Maneix L, Insunza J, Nalvarte I, Antonson P, Kere J, Yu NY, Tohonen V, Katayama S, Einarsdottir E, Krjutskov K, Dai YB, Huang B, Su W, Warner M, Gustafsson J?
Estrogen receptor ?, a regulator of androgen receptor signaling in the mouse ventral prostate. Proc Natl Acad Sci U S A. 2017 05 09; 114(19):E3816-E3822.
Estrogen receptor ?, a regulator of androgen receptor signaling in the mouse ventral prostate.
Zhang X, Li S, Zhou Y, Su W, Ruan X, Wang B, Zheng F, Warner M, Gustafsson J?, Guan Y
Ablation of cytochrome P450 omega-hydroxylase 4A14 gene attenuates hepatic steatosis and fibrosis. Proc Natl Acad Sci U S A. 2017 03 21; 114(12):3181-3185.
Ablation of cytochrome P450 omega-hydroxylase 4A14 gene attenuates hepatic steatosis and fibrosis.
Estrogen Receptor ? as a Pharmaceutical Target. Trends Pharmacol Sci. 2017 01; 38(1):92-99.
Estrogen Receptor ? as a Pharmaceutical Target.
Miao YF, Su W, Dai YB, Wu WF, Huang B, Barros RP, Nguyen H, Maneix L, Guan YF, Warner M, Gustafsson J?
An ER? agonist induces browning of subcutaneous abdominal fat pad in obese female mice. Sci Rep. 2016 12 06; 6:38579.
An ER? agonist induces browning of subcutaneous abdominal fat pad in obese female mice.
Abdel-Khalik J, Yutuc E, Crick PJ, Gustafsson J?, Warner M, Roman G, Talbot K, Gray E, Griffiths WJ, Turner MR, Wang Y
Defective cholesterol metabolism in amyotrophic lateral sclerosis. J Lipid Res. 2017 01; 58(1):267-278.
Defective cholesterol metabolism in amyotrophic lateral sclerosis.
Huang B, Butler R, Miao Y, Dai Y, Wu W, Su W, Fujii-Kuriyama Y, Warner M, Gustafsson J?
Dysregulation of Notch and ERa signaling in AhR-/- male mice. Proc Natl Acad Sci U S A. 2016 10 18; 113(42):11883-11888.
Dysregulation of Notch and ERa signaling in AhR-/- male mice.
Dai YB, Miao YF, Wu WF, Li Y, D'Errico F, Su W, Burns AR, Huang B, Maneix L, Warner M, Gustafsson J?
Ablation of Liver X receptors a and ? leads to spontaneous peripheral squamous cell lung cancer in mice. Proc Natl Acad Sci U S A. 2016 07 05; 113(27):7614-9.
Ablation of Liver X receptors a and ? leads to spontaneous peripheral squamous cell lung cancer in mice.
Bao X, Cai Y, Wang Y, Zhao J, He X, Yu D, Huang J, Jing S, Du Z, Yang T, Warner M, Gustafsson JA, Fan X
Liver X Receptor ? Is Involved in Formalin-Induced Spontaneous Pain. Mol Neurobiol. 2017 03; 54(2):1467-1481.
Liver X Receptor ? Is Involved in Formalin-Induced Spontaneous Pain.
Miao Y, Wu W, Dai Y, Maneix L, Huang B, Warner M, Gustafsson J?
Liver X receptor ? controls thyroid hormone feedback in the brain and regulates browning of subcutaneous white adipose tissue. Proc Natl Acad Sci U S A. 2015 Nov 10; 112(45):14006-11.
Liver X receptor ? controls thyroid hormone feedback in the brain and regulates browning of subcutaneous white adipose tissue.
Maneix L, Antonson P, Humire P, Rochel-Maia S, Casta?eda J, Omoto Y, Kim HJ, Warner M, Gustafsson J?
Estrogen receptor ? exon 3-deleted mouse: The importance of non-ERE pathways in ER? signaling. Proc Natl Acad Sci U S A. 2015 Apr 21; 112(16):5135-40.
Estrogen receptor ? exon 3-deleted mouse: The importance of non-ERE pathways in ER? signaling.
Estrogen receptors in breast carcinogenesis and endocrine therapy. Mol Cell Endocrinol. 2015 Dec 15; 418 Pt 3:240-4.
Estrogen receptors in breast carcinogenesis and endocrine therapy.
DHEA - a precursor of ER? ligands. J Steroid Biochem Mol Biol. 2015 Jan; 145:245-7.
Huang B, Omoto Y, Iwase H, Yamashita H, Toyama T, Coombes RC, Filipovic A, Warner M, Gustafsson J?
Differential expression of estrogen receptor a, ?1, and ?2 in lobular and ductal breast cancer. Proc Natl Acad Sci U S A. 2014 Feb 04; 111(5):1933-8.
Differential expression of estrogen receptor a, ?1, and ?2 in lobular and ductal breast cancer.
Biochemical and biophysical research communications
Action mechanisms of Liver X Receptors. Biochem Biophys Res Commun. 2014 Apr 11; 446(3):647-50.
Dey P, Barros RP, Warner M, Str?m A, Gustafsson J?
Insight into the mechanisms of action of estrogen receptor ? in the breast, prostate, colon, and CNS. J Mol Endocrinol. 2013 Dec; 51(3):T61-74.
Insight into the mechanisms of action of estrogen receptor ? in the breast, prostate, colon, and CNS.
Wu WF, Tan XJ, Dai YB, Krishnan V, Warner M, Gustafsson J?
Targeting estrogen receptor ? in microglia and T cells to treat experimental autoimmune encephalomyelitis. Proc Natl Acad Sci U S A. 2013 Feb 26; 110(9):3543-8.
Targeting estrogen receptor ? in microglia and T cells to treat experimental autoimmune encephalomyelitis.
Dai YB, Tan XJ, Wu WF, Warner M, Gustafsson J?
Liver X receptor ? protects dopaminergic neurons in a mouse model of Parkinson disease. Proc Natl Acad Sci U S A. 2012 Aug 07; 109(32):13112-7.
Liver X receptor ? protects dopaminergic neurons in a mouse model of Parkinson disease.
Tan XJ, Dai YB, Wu WF, Warner M, Gustafsson J?
Anxiety in liver X receptor ? knockout female mice with loss of glutamic acid decarboxylase in ventromedial prefrontal cortex. Proc Natl Acad Sci U S A. 2012 May 08; 109(19):7493-8.
Anxiety in liver X receptor ? knockout female mice with loss of glutamic acid decarboxylase in ventromedial prefrontal cortex.
Tan XJ, Dai YB, Wu WF, Kim HJ, Barros RP, Richardson TI, Yaden BC, Warner M, McKinzie DL, Krishnan V, Gustafsson J?
Reduction of dendritic spines and elevation of GABAergic signaling in the brains of mice treated with an estrogen receptor ? ligand. Proc Natl Acad Sci U S A. 2012 Jan 31; 109(5):1708-12.
Reduction of dendritic spines and elevation of GABAergic signaling in the brains of mice treated with an estrogen receptor ? ligand.
Butler R, Inzunza J, Suzuki H, Fujii-Kuriyama Y, Warner M, Gustafsson J?
Uric acid stones in the urinary bladder of aryl hydrocarbon receptor (AhR) knockout mice. Proc Natl Acad Sci U S A. 2012 Jan 24; 109(4):1122-6.
Uric acid stones in the urinary bladder of aryl hydrocarbon receptor (AhR) knockout mice.
Sugiyama N, Barros RP, Warner M, Gustafsson JA
Trends in endocrinology and metabolism: TEM
ERbeta: recent understanding of estrogen signaling. Trends Endocrinol Metab. 2010 Sep; 21(9):545-52.
ERbeta: recent understanding of estrogen signaling.
Tan XJ, Fan XT, Kim HJ, Butler R, Webb P, Warner M, Gustafsson JA
Liver X receptor beta and thyroid hormone receptor alpha in brain cortical layering. Proc Natl Acad Sci U S A. 2010 Jul 06; 107(27):12305-10.
Liver X receptor beta and thyroid hormone receptor alpha in brain cortical layering.