Pharmaceutical Health Outcomes and Policy
Pharmacy Practice and Translational Research
Singh G, Orman MA, Conrad JC, Nikolaou M
Systematic design of pulse dosing to eradicate persister bacteria. PLoS Comput Biol. 2023 01; 19(1):e1010243.
Systematic design of pulse dosing to eradicate persister bacteria.
Eales BM, Smith J, Pouya N, Hudson CS, Tam VH, Nikolaou M
Rapid Design of Combination Antimicrobial Therapy against Acinetobacter baumannii. Comput Chem Eng. 2025 Jan; 192.
Rapid Design of Combination Antimicrobial Therapy against Acinetobacter baumannii.
Hudson CS, Smith JE, Eales BM, Nikolaou M, Tam VH
International journal of antimicrobial agents
In vitro model to simulate multiple drugs with distinct elimination half-lives. Int J Antimicrob Agents. 2023 Oct; 62(4):106924.
In vitro model to simulate multiple drugs with distinct elimination half-lives.
Rapid In Vitro Assessment of Antimicrobial Drug Effect Bridging Clinically Relevant Pharmacokinetics: A Comprehensive Methodology. Pharmaceutics. 2023 Jun 07; 15(6).
Rapid In Vitro Assessment of Antimicrobial Drug Effect Bridging Clinically Relevant Pharmacokinetics: A Comprehensive Methodology.
Kesisoglou I, Eales BM, Merlau PR, Tam VH, Nikolaou M
Computer methods and programs in biomedicine
Deciphering longitudinal optical-density measurements to guide clinical dosing regimen design: A model-based approach. Comput Methods Programs Biomed. 2022 Dec; 227:107212.
Deciphering longitudinal optical-density measurements to guide clinical dosing regimen design: A model-based approach.
Revisiting the standard for modeling the spread of infectious diseases. Sci Rep. 2022 04 30; 12(1):7077.
Revisiting the standard for modeling the spread of infectious diseases.
Kesisoglou I, Tam VH, Tomaras AP, Nikolaou M
Discerning in vitro pharmacodynamics from OD measurements: A model-based approach. Comput Chem Eng. 2022 Feb; 158.
Discerning in vitro pharmacodynamics from OD measurements: A model-based approach.
Ziegler and Nichols meet Kermack and McKendrick: Parsimony in dynamic models for epidemiology. Comput Chem Eng. 2022 Jan; 157:107615.
Ziegler and Nichols meet Kermack and McKendrick: Parsimony in dynamic models for epidemiology.
Kesisoglou I, Eales BM, Ledesma KR, Merlau PR, Tam VH, Wang W, Nikolaou M
SIMULTANEOUS IN VITRO SIMULATION OF MULTIPLE ANTIMICROBIAL AGENTS WITH DIFFERENT ELIMINATION HALF-LIVES IN A PRE-CLINICAL INFECTION MODEL. Comput Chem Eng. 2021 Dec; 155.
SIMULTANEOUS IN VITRO SIMULATION OF MULTIPLE ANTIMICROBIAL AGENTS WITH DIFFERENT ELIMINATION HALF-LIVES IN A PRE-CLINICAL INFECTION MODEL.
Eales BM, Hudson CS, Kesisoglou I, Wang W, Nikolaou M, Tam VH
Experimental Validation of a Mathematical Framework to Simulate Antibiotics with Distinct Half-Lives Concurrently in an In Vitro Model. Antibiotics (Basel). 2021 Oct 16; 10(10).
Experimental Validation of a Mathematical Framework to Simulate Antibiotics with Distinct Half-Lives Concurrently in an In Vitro Model.
The Lambert Function Should Be in the Engineering Mathematical Toolbox. Comput Chem Eng. 2021 May; 148.
The Lambert Function Should Be in the Engineering Mathematical Toolbox.
Tam VH, Abodakpi H, Wang W, Ledesma KR, Merlau PR, Chan K, Altman R, Tran TT, Nikolaou M, Sofjan AK
The Journal of antimicrobial chemotherapy
Optimizing pharmacokinetics/pharmacodynamics of ?-lactam/?-lactamase inhibitor combinations against high inocula of ESBL-producing bacteria. J Antimicrob Chemother. 2021 01 01; 76(1):179-183.
Optimizing pharmacokinetics/pharmacodynamics of ?-lactam/?-lactamase inhibitor combinations against high inocula of ESBL-producing bacteria.
AIChE journal. American Institute of Chemical Engineers
Modeling Heterogeneous Bacterial Populations Exposed to Antibiotics: The Logistic-Dynamics Case. AIChE J. 2015 Aug; 61(8):2385-2393.
Modeling Heterogeneous Bacterial Populations Exposed to Antibiotics: The Logistic-Dynamics Case.
Tan MW, Lye DC, Ng TM, Nikolaou M, Tam VH
Mathematical model to quantify the effects of risk factors on carbapenem-resistant Acinetobacter baumannii. Antimicrob Agents Chemother. 2014 Sep; 58(9):5239-44.
Mathematical model to quantify the effects of risk factors on carbapenem-resistant Acinetobacter baumannii.
Bhagunde P, Chang KT, Hirsch EB, Ledesma KR, Nikolaou M, Tam VH
Novel modeling framework to guide design of optimal dosing strategies for ?-lactamase inhibitors. Antimicrob Agents Chemother. 2012 May; 56(5):2237-40.
Novel modeling framework to guide design of optimal dosing strategies for ?-lactamase inhibitors.
Guo B, Abdelraouf K, Ledesma KR, Nikolaou M, Tam VH
Predicting bacterial fitness cost associated with drug resistance. J Antimicrob Chemother. 2012 Apr; 67(4):928-32.
Predicting bacterial fitness cost associated with drug resistance.
Guo B, Abdelraouf K, Ledesma KR, Chang KT, Nikolaou M, Tam VH
Quantitative impact of neutrophils on bacterial clearance in a murine pneumonia model. Antimicrob Agents Chemother. 2011 Oct; 55(10):4601-5.
Quantitative impact of neutrophils on bacterial clearance in a murine pneumonia model.
Bhagunde P, Singh R, Ledesma KR, Chang KT, Nikolaou M, Tam VH
Modelling biphasic killing of fluoroquinolones: guiding optimal dosing regimen design. J Antimicrob Chemother. 2011 May; 66(5):1079-86.
Modelling biphasic killing of fluoroquinolones: guiding optimal dosing regimen design.
A novel approach to pharmacodynamic assessment of antimicrobial agents: new insights to dosing regimen design. PLoS Comput Biol. 2011 Jan 06; 7(1):e1001043.
A novel approach to pharmacodynamic assessment of antimicrobial agents: new insights to dosing regimen design.
Bhagunde P, Chang KT, Singh R, Singh V, Garey KW, Nikolaou M, Tam VH
Mathematical modeling to characterize the inoculum effect. Antimicrob Agents Chemother. 2010 Nov; 54(11):4739-43.
Mathematical modeling to characterize the inoculum effect.
Foster WJ, Dowla N, Joshi SY, Nikolaou M
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
The fluid mechanics of scleral buckling surgery for the repair of retinal detachment. Graefes Arch Clin Exp Ophthalmol. 2010 Jan; 248(1):31-6.
The fluid mechanics of scleral buckling surgery for the repair of retinal detachment.
Tam VH, Ledesma KR, Vo G, Kabbara S, Lim TP, Nikolaou M
Pharmacodynamic modeling of aminoglycosides against Pseudomonas aeruginosa and Acinetobacter baumannii: identifying dosing regimens to suppress resistance development. Antimicrob Agents Chemother. 2008 Nov; 52(11):3987-93.
Pharmacodynamic modeling of aminoglycosides against Pseudomonas aeruginosa and Acinetobacter baumannii: identifying dosing regimens to suppress resistance development.
Tam VH, Schilling AN, Poole K, Nikolaou M
Mathematical modelling response of Pseudomonas aeruginosa to meropenem. J Antimicrob Chemother. 2007 Dec; 60(6):1302-9.
Mathematical modelling response of Pseudomonas aeruginosa to meropenem.
Nikolaou M, Schilling AN, Vo G, Chang KT, Tam VH
Modeling of microbial population responses to time-periodic concentrations of antimicrobial agents. Ann Biomed Eng. 2007 Aug; 35(8):1458-70.
Modeling of microbial population responses to time-periodic concentrations of antimicrobial agents.
A new modeling approach to the effect of antimicrobial agents on heterogeneous microbial populations. J Math Biol. 2006 Feb; 52(2):154-82.
A new modeling approach to the effect of antimicrobial agents on heterogeneous microbial populations.
Modelling time-kill studies to discern the pharmacodynamics of meropenem. J Antimicrob Chemother. 2005 May; 55(5):699-706.
Modelling time-kill studies to discern the pharmacodynamics of meropenem.