Pharmaceutical Health Outcomes and Policy
Pharmacological and Pharmaceutical Sciences
Zheng Z, Chen J, Srinual S, Tumbas ?aponjac V, Yin T, Wang BY, Sun R, Hu M
Buprenorphine Salivary Gland Accumulation Sustaining High Oral Fluid Exposure and Increasing the Risk of Streptococcus mutans Biofilm Formation. J Addict Med. 2024 Dec 02.
Buprenorphine Salivary Gland Accumulation Sustaining High Oral Fluid Exposure and Increasing the Risk of Streptococcus mutans Biofilm Formation.
Zheng Z, ?aponjac VT, Singh R, Chen J, Srinual S, Yin T, Sun R, Hu M
Correction: Fecal SN-38 Content as a Surrogate Predictor of Intestinal SN-38 Exposure and Associated Irinotecan-induced Severe Delayed-Onset Diarrhea by a Novel Use of the Spectrofluorimetric Method. Pharm Res. 2024 Oct; 41(10):2075.
Correction: Fecal SN-38 Content as a Surrogate Predictor of Intestinal SN-38 Exposure and Associated Irinotecan-induced Severe Delayed-Onset Diarrhea by a Novel Use of the Spectrofluorimetric Method.
Fecal SN-38 Content as a Surrogate Predictor of Intestinal SN-38 Exposure and Associated Irinotecan-induced Severe Delayed-Onset Diarrhea by a Novel Use of the Spectrofluorimetric Method. Pharm Res. 2024 Sep; 41(9):1855-1867.
Fecal SN-38 Content as a Surrogate Predictor of Intestinal SN-38 Exposure and Associated Irinotecan-induced Severe Delayed-Onset Diarrhea by a Novel Use of the Spectrofluorimetric Method.
Zheng Z, Du T, Gao S, Yin T, Li L, Zhu L, Singh R, Sun R, Hu M
Optimized rat models better mimic patients with irinotecan-induced severe diarrhea. Toxicol Mech Methods. 2024 Jun; 34(5):572-583.
Optimized rat models better mimic patients with irinotecan-induced severe diarrhea.
Zheng Z, Srinual S, Chen J, Li L, Du T, Hu M, Sun R, Gao S
Herbal Medicines as Adjuvants for the Treatment of Chemotherapy-Induced Diarrhea. Curr Drug Metab. 2023; 24(6):422-433.
Herbal Medicines as Adjuvants for the Treatment of Chemotherapy-Induced Diarrhea.
Xie Z, Wang L, Chen J, Zheng Z, Srinual S, Guo A, Sun R, Hu M
Reduction of systemic exposure and side effects by intra-articular injection of anti-inflammatory agents for osteoarthritis: what is the safer strategy? J Drug Target. 2023 07; 31(6):596-611.
Reduction of systemic exposure and side effects by intra-articular injection of anti-inflammatory agents for osteoarthritis: what is the safer strategy?
Li L, Sun R, Zenga J, Himburg H, Wang L, Duan S, Liu J, Bui D, Xie Z, Du T, Xie L, Yin T, Wong S, Gao S, Hu M
Comparison of Absolute Expression and Turnover Number of COX-1 and COX-2 in Human and Rodent Cells and Tissues. J Inflamm Res. 2022; 15:4435-4447.
Comparison of Absolute Expression and Turnover Number of COX-1 and COX-2 in Human and Rodent Cells and Tissues.
Gao S, Sun R, Singh R, Yu So S, Chan CTY, Savidge T, Hu M
The role of gut microbial ?-glucuronidase in drug disposition and development. Drug Discov Today. 2022 10; 27(10):103316.
The role of gut microbial ?-glucuronidase in drug disposition and development.
Du T, Sun R, Etim I, Zheng Z, Liang D, Hu M, Gao S
Age-and Region-Dependent Disposition of Raloxifene in Rats. Pharm Res. 2021 Aug; 38(8):1357-1367.
Age-and Region-Dependent Disposition of Raloxifene in Rats.
Du T, Sun R, Siddiqui N, Moatamed L, Zhang Y, Liang D, Hu M, Gao S
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
A positive-negative switching LC-MS/MS method for quantification of fenoldopam and its phase II metabolites: Applications to a pharmacokinetic study in rats. J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Aug 01; 1179:122854.
J Chromatogr B Analyt Technol Biomed Life Sci
A positive-negative switching LC-MS/MS method for quantification of fenoldopam and its phase II metabolites: Applications to a pharmacokinetic study in rats.
Du T, Sun R, Li L, Ebuzoeme C, Bui D, Zheng Z, Yin T, Liang D, Hu M, Gao S
Development and validation of ultra-high-performance liquid chromatography-mass spectrometry method for the determination of raloxifene and its phase II metabolites in plasma: Application to pharmacokinetic studies in rats. J Sep Sci. 2020 Dec; 43(24):4414-4423.
Development and validation of ultra-high-performance liquid chromatography-mass spectrometry method for the determination of raloxifene and its phase II metabolites in plasma: Application to pharmacokinetic studies in rats.
Sun R, Zhu L, Li L, Song W, Gong X, Qi X, Wang Y, Ghose R, Gao S, Hu M, Liu Z
Irinotecan-mediated diarrhea is mainly correlated with intestinal exposure to SN-38: Critical role of gut Ugt. Toxicol Appl Pharmacol. 2020 07 01; 398:115032.
Irinotecan-mediated diarrhea is mainly correlated with intestinal exposure to SN-38: Critical role of gut Ugt.
Du T, Sun R, Du S, Gao S, Hu M, Zhang Y, Chen J, Yang G
Metabolic profiles of Xiao Chai Hu Tang in mouse plasma, bile and urine by the UHPLC-ESI-Q-TOF/MS technique. J Chromatogr B Analyt Technol Biomed Life Sci. 2019 Oct 01; 1128:121767.
Metabolic profiles of Xiao Chai Hu Tang in mouse plasma, bile and urine by the UHPLC-ESI-Q-TOF/MS technique.
Sun R, Basu S, Zeng M, Sunsong R, Li L, Ghose R, Wang W, Liu Z, Hu M, Gao S
Xiao-Chai-Hu-Tang (XCHT) Intervening Irinotecan's Disposition: The Potential of XCHT in Alleviating Irinotecan-Induced Diarrhea. Curr Cancer Drug Targets. 2019; 19(7):551-560.
Xiao-Chai-Hu-Tang (XCHT) Intervening Irinotecan's Disposition: The Potential of XCHT in Alleviating Irinotecan-Induced Diarrhea.
Li Y, Song W, Ou X, Luo G, Xie Y, Sun R, Wang Y, Qi X, Hu M, Liu Z, Zhu L
Drug metabolism and disposition: the biological fate of chemicals
Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Determine the Disposition of Esculetin-7-O-Glucuronide and 4-Methylesculetin-7-O-Glucuronide. Drug Metab Dispos. 2019 03; 47(3):203-214.
Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Determine the Disposition of Esculetin-7-O-Glucuronide and 4-Methylesculetin-7-O-Glucuronide.
Wang L, Sun R, Zhang Q, Luo Q, Zeng S, Li X, Gong X, Li Y, Lu L, Hu M, Liu Z
Expert opinion on drug metabolism & toxicology
An update on polyphenol disposition via coupled metabolic pathways. Expert Opin Drug Metab Toxicol. 2019 Feb; 15(2):151-165.
An update on polyphenol disposition via coupled metabolic pathways.
Zeng M, Sun R, Basu S, Ma Y, Ge S, Yin T, Gao S, Zhang J, Hu M
Disposition of flavonoids via recycling: Direct biliary excretion of enterically or extrahepatically derived flavonoid glucuronides. Mol Nutr Food Res. 2016 May; 60(5):1006-19.
Disposition of flavonoids via recycling: Direct biliary excretion of enterically or extrahepatically derived flavonoid glucuronides.
Sun R, Zeng M, Du T, Li L, Yang G, Hu M, Gao S
Simultaneous determinations of 17 marker compounds in Xiao-Chai-Hu-Tang by LC-MS/MS: Application to its pharmacokinetic studies in mice. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 15; 1003:12-21.
Simultaneous determinations of 17 marker compounds in Xiao-Chai-Hu-Tang by LC-MS/MS: Application to its pharmacokinetic studies in mice.
Development and validation of an UPLC-MS/MS method for the quantification of columbin in biological matrices: Applications to absorption, metabolism, and pharmacokinetic studies. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 01; 1002:13-8.
Development and validation of an UPLC-MS/MS method for the quantification of columbin in biological matrices: Applications to absorption, metabolism, and pharmacokinetic studies.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Role of MRPs transporters in pharmacokinetics and intestinal toxicity of irinotecan. Food Chem Toxicol. 2023 Dec; 182:114171.
Role of MRPs transporters in pharmacokinetics and intestinal toxicity of irinotecan.
Wang C, Teng X, Wang C, Liu B, Zhou R, Xu X, Qiu H, Fu Y, Sun R, Liang Z, Zhang R, Liu Z, Zhang L, Zhu L
Phytomedicine : international journal of phytotherapy and phytopharmacology
Insight into the mechanism of Xiao-Chai-Hu-Tang alleviates irinotecan-induced diarrhea based on regulating the gut microbiota and inhibiting Gut ß-GUS. Phytomedicine. 2023 Nov; 120:155040.
Insight into the mechanism of Xiao-Chai-Hu-Tang alleviates irinotecan-induced diarrhea based on regulating the gut microbiota and inhibiting Gut ß-GUS.
Zhou J, He X, Sun R, Yu Z, Wang C, Deng S, Zhang B, Huang S, Han C, Li D
Lignans from Bupleurum marginatum and their antioxidant activity. Nat Prod Res. 2022 Oct; 36(19):5016-5021.
Lignans from Bupleurum marginatum and their antioxidant activity.
Disposition of flavonoids impacts their efficacy and safety. Curr Drug Metab. 2014; 15(9):841-64.
Disposition of flavonoids impacts their efficacy and safety.