Sun, Rongjin
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research areas: Diarrhea
research areas: Drugs, Chinese Herbal
research areas: Intestines
research areas: Biliary Tract
research areas: Glucuronosyltransferase
mailing address: https://profilesrns.times.uh.edu/profile/172868
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Biliary Tract
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Authorship 8995
type: Authorship
author rank in publication: 7
linked author: Sun, Rongjin
linked information resource: Buprenorphine Salivary Gland Accumulation Sustaining High Oral Fluid Exposure and Increasing the Risk of Streptococcus mutans Biofilm Formation.

Authorship 8996
type: Authorship
author rank in publication: 7
linked author: Sun, Rongjin
linked information resource: Correction: Fecal SN-38 Content as a Surrogate Predictor of Intestinal SN-38 Exposure and Associated Irinotecan-induced Severe Delayed-Onset Diarrhea by a Novel Use of the Spectrofluorimetric Method.

Authorship 8997
type: Authorship
author rank in publication: 7
linked author: Sun, Rongjin
linked information resource: Fecal SN-38 Content as a Surrogate Predictor of Intestinal SN-38 Exposure and Associated Irinotecan-induced Severe Delayed-Onset Diarrhea by a Novel Use of the Spectrofluorimetric Method.

Authorship 8998
type: Authorship
author rank in publication: 8
linked author: Sun, Rongjin
linked information resource: Optimized rat models better mimic patients with irinotecan-induced severe diarrhea.

Authorship 8999
type: Authorship
author rank in publication: 4
linked author: Sun, Rongjin
linked information resource: Role of MRPs transporters in pharmacokinetics and intestinal toxicity of irinotecan.

Authorship 9000
type: Authorship
author rank in publication: 9
linked author: Sun, Rongjin
linked information resource: Insight into the mechanism of Xiao-Chai-Hu-Tang alleviates irinotecan-induced diarrhea based on regulating the gut microbiota and inhibiting Gut ß-GUS.

Authorship 9001
type: Authorship
author rank in publication: 7
linked author: Sun, Rongjin
linked information resource: Herbal Medicines as Adjuvants for the Treatment of Chemotherapy-Induced Diarrhea.

Authorship 9002
type: Authorship
author rank in publication: 7
linked author: Sun, Rongjin
linked information resource: Reduction of systemic exposure and side effects by intra-articular injection of anti-inflammatory agents for osteoarthritis: what is the safer strategy?

Authorship 9003
type: Authorship
author rank in publication: 2
linked author: Sun, Rongjin
linked information resource: Comparison of Absolute Expression and Turnover Number of COX-1 and COX-2 in Human and Rodent Cells and Tissues.

Authorship 9004
type: Authorship
author rank in publication: 2
linked author: Sun, Rongjin
linked information resource: The role of gut microbial ?-glucuronidase in drug disposition and development.

Authorship 9005
type: Authorship
author rank in publication: 2
linked author: Sun, Rongjin
linked information resource: Age-and Region-Dependent Disposition of Raloxifene in Rats.

Authorship 9006
type: Authorship
author rank in publication: 2
linked author: Sun, Rongjin
linked information resource: A positive-negative switching LC-MS/MS method for quantification of fenoldopam and its phase II metabolites: Applications to a pharmacokinetic study in rats.

Authorship 9007
type: Authorship
author rank in publication: 3
linked author: Sun, Rongjin
linked information resource: Lignans from Bupleurum marginatum and their antioxidant activity.

Authorship 9008
type: Authorship
author rank in publication: 2
linked author: Sun, Rongjin
linked information resource: https://profilesrns.times.uh.edu/profile/343868

Authorship 9009
type: Authorship
author rank in publication: 1
linked author: Sun, Rongjin
linked information resource: Irinotecan-mediated diarrhea is mainly correlated with intestinal exposure to SN-38: Critical role of gut Ugt.

Authorship 9010
type: Authorship
author rank in publication: 2
linked author: Sun, Rongjin
linked information resource: Metabolic profiles of Xiao Chai Hu Tang in mouse plasma, bile and urine by the UHPLC-ESI-Q-TOF/MS technique.

Authorship 9011
type: Authorship
author rank in publication: 1
linked author: Sun, Rongjin
linked information resource: Xiao-Chai-Hu-Tang (XCHT) Intervening Irinotecan's Disposition: The Potential of XCHT in Alleviating Irinotecan-Induced Diarrhea.

Authorship 9012
type: Authorship
author rank in publication: 6
linked author: Sun, Rongjin
linked information resource: Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Determine the Disposition of Esculetin-7-O-Glucuronide and 4-Methylesculetin-7-O-Glucuronide.

Authorship 9013
type: Authorship
author rank in publication: 2
linked author: Sun, Rongjin
linked information resource: An update on polyphenol disposition via coupled metabolic pathways.

Authorship 9014
type: Authorship
author rank in publication: 2
linked author: Sun, Rongjin
linked information resource: Disposition of flavonoids via recycling: Direct biliary excretion of enterically or extrahepatically derived flavonoid glucuronides.

Authorship 9015
type: Authorship
author rank in publication: 1
linked author: Sun, Rongjin
linked information resource: Simultaneous determinations of 17 marker compounds in Xiao-Chai-Hu-Tang by LC-MS/MS: Application to its pharmacokinetic studies in mice.

Authorship 9016
type: Authorship
author rank in publication: 3
linked author: Sun, Rongjin
linked information resource: Development and validation of an UPLC-MS/MS method for the quantification of columbin in biological matrices: Applications to absorption, metabolism, and pharmacokinetic studies.

Authorship 9017
type: Authorship
author rank in publication: 3
linked author: Sun, Rongjin
linked information resource: Disposition of flavonoids impacts their efficacy and safety.

Buprenorphine Salivary Gland Accumulation Sustaining High Oral Fluid Exposure and Increasing the Risk of Streptococcus mutans Biofilm Formation.
PubMed Identifier: 39621545
author list: Zheng Z, Chen J, Srinual S, Tumbas ?aponjac V, Yin T, Wang BY, Sun R, Hu M
published in: Journal of addiction medicine
information resource reference: Buprenorphine Salivary Gland Accumulation Sustaining High Oral Fluid Exposure and Increasing the Risk of Streptococcus mutans Biofilm Formation. J Addict Med. 2024 Dec 02.
journal title abbreviation: J Addict Med
publication date: 2024-12-02T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Correction: Fecal SN-38 Content as a Surrogate Predictor of Intestinal SN-38 Exposure and Associated Irinotecan-induced Severe Delayed-Onset Diarrhea by a Novel Use of the Spectrofluorimetric Method.
PubMed Identifier: 39349694
author list: Zheng Z, ?aponjac VT, Singh R, Chen J, Srinual S, Yin T, Sun R, Hu M
published in: Pharmaceutical research
information resource reference: Correction: Fecal SN-38 Content as a Surrogate Predictor of Intestinal SN-38 Exposure and Associated Irinotecan-induced Severe Delayed-Onset Diarrhea by a Novel Use of the Spectrofluorimetric Method. Pharm Res. 2024 Oct; 41(10):2075.
journal title abbreviation: Pharm Res
publication date: 2024-10-01T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Fecal SN-38 Content as a Surrogate Predictor of Intestinal SN-38 Exposure and Associated Irinotecan-induced Severe Delayed-Onset Diarrhea by a Novel Use of the Spectrofluorimetric Method.
PubMed Identifier: 39138788
author list: Zheng Z, ?aponjac VT, Singh R, Chen J, Srinual S, Yin T, Sun R, Hu M
published in: Pharmaceutical research
information resource reference: Fecal SN-38 Content as a Surrogate Predictor of Intestinal SN-38 Exposure and Associated Irinotecan-induced Severe Delayed-Onset Diarrhea by a Novel Use of the Spectrofluorimetric Method. Pharm Res. 2024 Sep; 41(9):1855-1867.
journal title abbreviation: Pharm Res
publication date: 2024-08-13T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Optimized rat models better mimic patients with irinotecan-induced severe diarrhea.
PubMed Identifier: 38390772
author list: Zheng Z, Du T, Gao S, Yin T, Li L, Zhu L, Singh R, Sun R, Hu M
published in: Toxicology mechanisms and methods
information resource reference: Optimized rat models better mimic patients with irinotecan-induced severe diarrhea. Toxicol Mech Methods. 2024 Jun; 34(5):572-583.
journal title abbreviation: Toxicol Mech Methods
publication date: 2024-02-23T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Herbal Medicines as Adjuvants for the Treatment of Chemotherapy-Induced Diarrhea.
PubMed Identifier: 37592799
author list: Zheng Z, Srinual S, Chen J, Li L, Du T, Hu M, Sun R, Gao S
published in: Current drug metabolism
information resource reference: Herbal Medicines as Adjuvants for the Treatment of Chemotherapy-Induced Diarrhea. Curr Drug Metab. 2023; 24(6):422-433.
journal title abbreviation: Curr Drug Metab
publication date: 2023-01-01T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Reduction of systemic exposure and side effects by intra-articular injection of anti-inflammatory agents for osteoarthritis: what is the safer strategy?
PubMed Identifier: 37249274
author list: Xie Z, Wang L, Chen J, Zheng Z, Srinual S, Guo A, Sun R, Hu M
published in: Journal of drug targeting
information resource reference: Reduction of systemic exposure and side effects by intra-articular injection of anti-inflammatory agents for osteoarthritis: what is the safer strategy? J Drug Target. 2023 07; 31(6):596-611.
journal title abbreviation: J Drug Target
publication date: 2023-06-09T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Comparison of Absolute Expression and Turnover Number of COX-1 and COX-2 in Human and Rodent Cells and Tissues.
PubMed Identifier: 35958187
author list: Li L, Sun R, Zenga J, Himburg H, Wang L, Duan S, Liu J, Bui D, Xie Z, Du T, Xie L, Yin T, Wong S, Gao S, Hu M
published in: Journal of inflammation research
information resource reference: Comparison of Absolute Expression and Turnover Number of COX-1 and COX-2 in Human and Rodent Cells and Tissues. J Inflamm Res. 2022; 15:4435-4447.
journal title abbreviation: J Inflamm Res
publication date: 2022-08-04T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

The role of gut microbial ?-glucuronidase in drug disposition and development.
PubMed Identifier: 35820618
author list: Gao S, Sun R, Singh R, Yu So S, Chan CTY, Savidge T, Hu M
published in: Drug discovery today
information resource reference: The role of gut microbial ?-glucuronidase in drug disposition and development. Drug Discov Today. 2022 10; 27(10):103316.
journal title abbreviation: Drug Discov Today
publication date: 2022-07-09T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Age-and Region-Dependent Disposition of Raloxifene in Rats.
PubMed Identifier: 34322833
author list: Du T, Sun R, Etim I, Zheng Z, Liang D, Hu M, Gao S
published in: Pharmaceutical research
information resource reference: Age-and Region-Dependent Disposition of Raloxifene in Rats. Pharm Res. 2021 Aug; 38(8):1357-1367.
journal title abbreviation: Pharm Res
publication date: 2021-07-28T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

A positive-negative switching LC-MS/MS method for quantification of fenoldopam and its phase II metabolites: Applications to a pharmacokinetic study in rats.
PubMed Identifier: 34242859
author list: Du T, Sun R, Siddiqui N, Moatamed L, Zhang Y, Liang D, Hu M, Gao S
published in: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
information resource reference: A positive-negative switching LC-MS/MS method for quantification of fenoldopam and its phase II metabolites: Applications to a pharmacokinetic study in rats. J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Aug 01; 1179:122854.
journal title abbreviation: J Chromatogr B Analyt Technol Biomed Life Sci
publication date: 2021-07-05T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

https://profilesrns.times.uh.edu/profile/343868
PubMed Identifier: 33119204
author list: Du T, Sun R, Li L, Ebuzoeme C, Bui D, Zheng Z, Yin T, Liang D, Hu M, Gao S
published in: Journal of separation science
information resource reference: Development and validation of ultra-high-performance liquid chromatography-mass spectrometry method for the determination of raloxifene and its phase II metabolites in plasma: Application to pharmacokinetic studies in rats. J Sep Sci. 2020 Dec; 43(24):4414-4423.
journal title abbreviation: J Sep Sci
publication date: 2020-11-20T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
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label: Development and validation of ultra-high-performance liquid chromatography-mass spectrometry method for the determination of raloxifene and its phase II metabolites in plasma: Application to pharmacokinetic studies in rats.

Irinotecan-mediated diarrhea is mainly correlated with intestinal exposure to SN-38: Critical role of gut Ugt.
PubMed Identifier: 32387182
author list: Sun R, Zhu L, Li L, Song W, Gong X, Qi X, Wang Y, Ghose R, Gao S, Hu M, Liu Z
published in: Toxicology and applied pharmacology
information resource reference: Irinotecan-mediated diarrhea is mainly correlated with intestinal exposure to SN-38: Critical role of gut Ugt. Toxicol Appl Pharmacol. 2020 07 01; 398:115032.
journal title abbreviation: Toxicol Appl Pharmacol
publication date: 2020-05-05T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Metabolic profiles of Xiao Chai Hu Tang in mouse plasma, bile and urine by the UHPLC-ESI-Q-TOF/MS technique.
PubMed Identifier: 31627161
author list: Du T, Sun R, Du S, Gao S, Hu M, Zhang Y, Chen J, Yang G
published in: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
information resource reference: Metabolic profiles of Xiao Chai Hu Tang in mouse plasma, bile and urine by the UHPLC-ESI-Q-TOF/MS technique. J Chromatogr B Analyt Technol Biomed Life Sci. 2019 Oct 01; 1128:121767.
journal title abbreviation: J Chromatogr B Analyt Technol Biomed Life Sci
publication date: 2019-08-17T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Xiao-Chai-Hu-Tang (XCHT) Intervening Irinotecan's Disposition: The Potential of XCHT in Alleviating Irinotecan-Induced Diarrhea.
PubMed Identifier: 31509102
author list: Sun R, Basu S, Zeng M, Sunsong R, Li L, Ghose R, Wang W, Liu Z, Hu M, Gao S
published in: Current cancer drug targets
information resource reference: Xiao-Chai-Hu-Tang (XCHT) Intervening Irinotecan's Disposition: The Potential of XCHT in Alleviating Irinotecan-Induced Diarrhea. Curr Cancer Drug Targets. 2019; 19(7):551-560.
journal title abbreviation: Curr Cancer Drug Targets
publication date: 2019-01-01T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Determine the Disposition of Esculetin-7-O-Glucuronide and 4-Methylesculetin-7-O-Glucuronide.
PubMed Identifier: 30602435
author list: Li Y, Song W, Ou X, Luo G, Xie Y, Sun R, Wang Y, Qi X, Hu M, Liu Z, Zhu L
published in: Drug metabolism and disposition: the biological fate of chemicals
information resource reference: Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Determine the Disposition of Esculetin-7-O-Glucuronide and 4-Methylesculetin-7-O-Glucuronide. Drug Metab Dispos. 2019 03; 47(3):203-214.
journal title abbreviation: Drug Metab Dispos
publication date: 2019-01-02T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

An update on polyphenol disposition via coupled metabolic pathways.
PubMed Identifier: 30583703
author list: Wang L, Sun R, Zhang Q, Luo Q, Zeng S, Li X, Gong X, Li Y, Lu L, Hu M, Liu Z
published in: Expert opinion on drug metabolism & toxicology
information resource reference: An update on polyphenol disposition via coupled metabolic pathways. Expert Opin Drug Metab Toxicol. 2019 Feb; 15(2):151-165.
journal title abbreviation: Expert Opin Drug Metab Toxicol
publication date: 2018-12-24T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Disposition of flavonoids via recycling: Direct biliary excretion of enterically or extrahepatically derived flavonoid glucuronides.
PubMed Identifier: 26843117
author list: Zeng M, Sun R, Basu S, Ma Y, Ge S, Yin T, Gao S, Zhang J, Hu M
published in: Molecular nutrition & food research
information resource reference: Disposition of flavonoids via recycling: Direct biliary excretion of enterically or extrahepatically derived flavonoid glucuronides. Mol Nutr Food Res. 2016 May; 60(5):1006-19.
journal title abbreviation: Mol Nutr Food Res
publication date: 2016-04-13T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Simultaneous determinations of 17 marker compounds in Xiao-Chai-Hu-Tang by LC-MS/MS: Application to its pharmacokinetic studies in mice.
PubMed Identifier: 26397748
author list: Sun R, Zeng M, Du T, Li L, Yang G, Hu M, Gao S
published in: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
information resource reference: Simultaneous determinations of 17 marker compounds in Xiao-Chai-Hu-Tang by LC-MS/MS: Application to its pharmacokinetic studies in mice. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 15; 1003:12-21.
journal title abbreviation: J Chromatogr B Analyt Technol Biomed Life Sci
publication date: 2015-09-11T00:00:00
year: 2015
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Development and validation of an UPLC-MS/MS method for the quantification of columbin in biological matrices: Applications to absorption, metabolism, and pharmacokinetic studies.
PubMed Identifier: 26295697
author list: Yang G, Gao S, Sun R, Yin T, Hu M
published in: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
information resource reference: Development and validation of an UPLC-MS/MS method for the quantification of columbin in biological matrices: Applications to absorption, metabolism, and pharmacokinetic studies. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 01; 1002:13-8.
journal title abbreviation: J Chromatogr B Analyt Technol Biomed Life Sci
publication date: 2015-08-07T00:00:00
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Role of MRPs transporters in pharmacokinetics and intestinal toxicity of irinotecan.
PubMed Identifier: 37956707
author list: Du T, Luo T, Wang J, Sun R, Cai H
published in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
information resource reference: Role of MRPs transporters in pharmacokinetics and intestinal toxicity of irinotecan. Food Chem Toxicol. 2023 Dec; 182:114171.
journal title abbreviation: Food Chem Toxicol
publication date: 2023-11-11T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Insight into the mechanism of Xiao-Chai-Hu-Tang alleviates irinotecan-induced diarrhea based on regulating the gut microbiota and inhibiting Gut ß-GUS.
PubMed Identifier: 37683587
author list: Wang C, Teng X, Wang C, Liu B, Zhou R, Xu X, Qiu H, Fu Y, Sun R, Liang Z, Zhang R, Liu Z, Zhang L, Zhu L
published in: Phytomedicine : international journal of phytotherapy and phytopharmacology
information resource reference: Insight into the mechanism of Xiao-Chai-Hu-Tang alleviates irinotecan-induced diarrhea based on regulating the gut microbiota and inhibiting Gut ß-GUS. Phytomedicine. 2023 Nov; 120:155040.
journal title abbreviation: Phytomedicine
publication date: 2023-08-19T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Lignans from Bupleurum marginatum and their antioxidant activity.
PubMed Identifier: 33908316
author list: Zhou J, He X, Sun R, Yu Z, Wang C, Deng S, Zhang B, Huang S, Han C, Li D
published in: Natural product research
information resource reference: Lignans from Bupleurum marginatum and their antioxidant activity. Nat Prod Res. 2022 Oct; 36(19):5016-5021.
journal title abbreviation: Nat Prod Res
publication date: 2021-04-28T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Disposition of flavonoids impacts their efficacy and safety.
PubMed Identifier: 25658129
author list: Ma Y, Zeng M, Sun R, Hu M
published in: Current drug metabolism
information resource reference: Disposition of flavonoids impacts their efficacy and safety. Curr Drug Metab. 2014; 15(9):841-64.
journal title abbreviation: Curr Drug Metab
publication date: 2014-01-01T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Diarrhea
MeSH DescriptorUI: D003967
MeSH semantic group name: Disorders
number of authors: 8
number of publications: 23
uniqueness weight: 0.970355
type: Concept

Associate Professor
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position in department: AccelNet
position in division: AccelNet
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HR job title: Associate Professor
position in organization: Arizona State University (ASU)

Professor
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position in department: Pharmaceutical Health Outcomes and Policy
position in division: Pharmacy, College of
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type: Position
HR job title: Professor
position in organization: University of Houston

Professor
is primary position: true
position in department: Pharmacological and Pharmaceutical Sciences
position in division: College of Pharmacy
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type: Position
HR job title: Professor
position in organization: University of Houston

Associate Professor
is primary position: true
position in department: Pharmacological and Pharmaceutical Sciences
position in division: College of Pharmacy
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HR job title: Associate Professor
position in organization: University of Houston

Associate Professor
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position in department: Pharmacological and Pharmaceutical Sciences
position in division: College of Pharmacy
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type: Position
HR job title: Associate Professor
position in organization: University of Houston

Professor
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position in department: Pharmacological and Pharmaceutical Sciences
position in division: College of Pharmacy
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type: Position
HR job title: Professor
position in organization: University of Houston

Assistant Professor
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position in department: Pharmacological and Pharmaceutical Sciences
position in division: College of Pharmacy
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HR job title: Assistant Professor
position in organization: University of Houston

Assistant Professor
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position in department: Pharmacological and Pharmaceutical Sciences
position in division: College of Pharmacy
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HR job title: Assistant Professor
position in organization: University of Houston

Glucuronosyltransferase
MeSH DescriptorUI: D014453
MeSH semantic group name: Chemicals & Drugs
number of authors: 5
number of publications: 30
uniqueness weight: 0.969149
type: Concept