Endres BT, Bassères E, Memariani A, Chang L, Alam MJ, Vickers RJ, Kakadiaris IA, Garey KW
A novel method for imaging the pharmacological effects of antibiotic treatment on Clostridium difficile. Anaerobe. 2016 Aug; 40:10-4.
A novel method for imaging the pharmacological effects of antibiotic treatment on Clostridium difficile.
Pharmaceutical Health Outcomes and Policy
Pharmacy Practice and Translational Research
Endres B, Bass?res E, Rashid T, Chang L, Alam MJ, Garey KW
Journal of visualized experiments : JoVE
A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment. J Vis Exp. 2017 05 25; (123).
A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment.
Jo J, Hu C, Horvath TD, Haidacher SJ, Begum K, Alam MJ, Garey KW
Phase I trial comparing bile acid and short-chain fatty acid alterations in stool collected from human subjects treated with omadacycline or vancomycin. Antimicrob Agents Chemother. 2025 Feb 13; 69(2):e0125124.
Phase I trial comparing bile acid and short-chain fatty acid alterations in stool collected from human subjects treated with omadacycline or vancomycin.
Begum K, Chua HC, Alam MJ, Garey KW, Jo J
A quantitative PCR to detect non-toxigenic Clostridioides difficile. Microbiol Spectr. 2025 Jan 07; 13(1):e0160824.
A quantitative PCR to detect non-toxigenic Clostridioides difficile.
Bass?res E, Eubank TA, Begum K, Alam MJ, Jo J, Le TM, Lancaster CK, Gonzales-Luna AJ, Garey KW
Antibacterial activity of ibezapolstat against antimicrobial-resistant clinical strains of Clostridioides difficile. Antimicrob Agents Chemother. 2024 03 06; 68(3):e0162123.
Antibacterial activity of ibezapolstat against antimicrobial-resistant clinical strains of Clostridioides difficile.
Zasowski EJ, Ali M, Anugo A, Ibragimova N, Dotson KM, Endres BT, Begum K, Alam MJ, Garey KW
Comparison of Risk Stratification Approaches to Identify Patients with Clostridioides difficile Infection at Risk for Multidrug-Resistant Organism Gut Microbiota Colonization. Infect Dis Ther. 2023 Aug; 12(8):2005-2015.
Comparison of Risk Stratification Approaches to Identify Patients with Clostridioides difficile Infection at Risk for Multidrug-Resistant Organism Gut Microbiota Colonization.
Mason CS, Avis T, Hu C, Nagalingam N, Mudaliar M, Coward C, Begum K, Gajewski K, Alam MJ, Bass?res E, Moss S, Reich S, Duperchy E, Fox KR, Garey KW, Powell DJ
The Novel DNA Binding Mechanism of Ridinilazole, a Precision Clostridiodes difficile Antibiotic. Antimicrob Agents Chemother. 2023 05 17; 67(5):e0156322.
The Novel DNA Binding Mechanism of Ridinilazole, a Precision Clostridiodes difficile Antibiotic.
Endres BT, Basseres E, Citron DM, Tyrrell KL, Begum K, Lancaster C, Warren YA, Alam MJ, Garey KW, Goldstein EJC
Fusobacteria behaving badly: Masquerading strains of strictly anaerobic Escherichiacoli misidentified due to the deletion of the hemB gene. Anaerobe. 2023 Feb; 79:102682.
Fusobacteria behaving badly: Masquerading strains of strictly anaerobic Escherichiacoli misidentified due to the deletion of the hemB gene.
Saha K, Kabir ND, Islam MR, Amin MB, Hoque KI, Halder K, Saleh AA, Parvez MAK, Begum K, Alam MJ, Islam MA
Journal of global antimicrobial resistance
Isolation and characterisation of carbapenem-resistant Pseudomonas aeruginosa from hospital environments in tertiary care hospitals in Dhaka, Bangladesh. J Glob Antimicrob Resist. 2022 09; 30:31-37.
Isolation and characterisation of carbapenem-resistant Pseudomonas aeruginosa from hospital environments in tertiary care hospitals in Dhaka, Bangladesh.
Rahman MM, Hossain MMK, Rubaya R, Halder J, Karim ME, Bhuiya AA, Khatun A, Alam J
The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale
Association of Antibiotic Resistance Traits in Uropathogenic Escherichia coli (UPEC) Isolates. Can J Infect Dis Med Microbiol. 2022; 2022:4251486.
Association of Antibiotic Resistance Traits in Uropathogenic Escherichia coli (UPEC) Isolates.
Mastor NNI, Subbiah VK, Bakar WNWA, Begum K, Alam MJ, Hoque MZ
Draft genome sequence data of a clinical Enterococcus faecalis isolate SHH039 from a patient with cholecystitis from a tertiary care hospital in Sabah, Malaysia. Data Brief. 2022 Apr; 41:108019.
Draft genome sequence data of a clinical Enterococcus faecalis isolate SHH039 from a patient with cholecystitis from a tertiary care hospital in Sabah, Malaysia.
Almutairi MS, Gonzales-Luna AJ, Alnezary FS, Fallatah SB, Alam MJ, Begum K, Garey KW
Comparative clinical outcomes evaluation of hospitalized patients infected with Clostridioides difficile ribotype 106 vs. other toxigenic strains. Anaerobe. 2021 Dec; 72:102440.
Comparative clinical outcomes evaluation of hospitalized patients infected with Clostridioides difficile ribotype 106 vs. other toxigenic strains.
Gonzales-Luna AJ, Olaitan AO, Shen WJ, Deshpande A, Carlson TJ, Dotson KM, Lancaster C, Begum K, Alam MJ, Hurdle JG, Garey KW
Reduced Susceptibility to Metronidazole Is Associated With Initial Clinical Failure in Clostridioides difficile Infection. Open Forum Infect Dis. 2021 Aug; 8(8):ofab365.
Reduced Susceptibility to Metronidazole Is Associated With Initial Clinical Failure in Clostridioides difficile Infection.
Gonzales-Luna AJ, Spinler JK, Oezguen N, Khan MAW, Danhof HA, Endres BT, Alam MJ, Begum K, Lancaster C, Costa GP, Savidge TC, Hurdle JG, Britton R, Garey KW
Systems biology evaluation of refractory Clostridioides difficile infection including multiple failures of fecal microbiota transplantation. Anaerobe. 2021 Aug; 70:102387.
Systems biology evaluation of refractory Clostridioides difficile infection including multiple failures of fecal microbiota transplantation.
Bass?res E, Endres BT, Montes-Bravo N, P?rez-Soto N, Rashid T, Lancaster C, Begum K, Alam MJ, Paredes-Sabja D, Garey KW
Visualization of fidaxomicin association with the exosporium layer of Clostridioides difficile spores. Anaerobe. 2021 Jun; 69:102352.
Visualization of fidaxomicin association with the exosporium layer of Clostridioides difficile spores.
Carlson TJ, Gonzales-Luna AJ, Nebo K, Chan HY, Tran NT, Antony S, Lancaster C, Alam MJ, Begum K, Garey KW
Assessment of Kidney Injury as a Severity Criteria for Clostridioides Difficile Infection. Open Forum Infect Dis. 2020 Nov; 7(11):ofaa476.
Assessment of Kidney Injury as a Severity Criteria for Clostridioides Difficile Infection.
Mastor NN, Subbiah VK, Bakar WNWA, Begum K, Alam MJ, Hoque MZ
Whole genome sequencing data of a clinical Enterococcus gallinarum strain EGR748 from Sabah, Malaysia. Data Brief. 2020 Dec; 33:106370.
Whole genome sequencing data of a clinical Enterococcus gallinarum strain EGR748 from Sabah, Malaysia.
Garey KW, Begum K, Lancaster C, Gonzales-Luna A, Bui D, Mercier J, Seng Yue C, Ducharme MP, Hu M, Vince B, Silverman MH, Alam MJ, Kankam M
The Journal of antimicrobial chemotherapy
A randomized, double-blind, placebo-controlled, single and multiple ascending dose Phase 1 study to determine the safety, pharmacokinetics and food and faecal microbiome effects of ibezapolstat administered orally to healthy subjects. J Antimicrob Chemother. 2020 12 01; 75(12):3635-3643.
A randomized, double-blind, placebo-controlled, single and multiple ascending dose Phase 1 study to determine the safety, pharmacokinetics and food and faecal microbiome effects of ibezapolstat administered orally to healthy subjects.
Bass?res E, Begum K, Lancaster C, Gonzales-Luna AJ, Carlson TJ, Miranda J, Rashid T, Alam MJ, Eyre DW, Wilcox MH, Garey KW
In vitro activity of eravacycline against common ribotypes of Clostridioides difficile. J Antimicrob Chemother. 2020 10 01; 75(10):2879-2884.
In vitro activity of eravacycline against common ribotypes of Clostridioides difficile.
Begum K, Bass?res E, Miranda J, Lancaster C, Gonzales-Luna AJ, Carlson TJ, Rashid T, Eyre DW, Wilcox MH, Alam MJ, Garey KW
In Vitro Activity of Omadacycline, a New Tetracycline Analog, and Comparators against Clostridioides difficile. Antimicrob Agents Chemother. 2020 07 22; 64(8).
In Vitro Activity of Omadacycline, a New Tetracycline Analog, and Comparators against Clostridioides difficile.
Gonzales-Luna AJ, Carlson TJ, Dotson KM, Poblete K, Costa G, Miranda J, Lancaster C, Walk ST, Tupy S, Begum K, Alam MJ, Garey KW
PCR ribotypes of Clostridioides difficile across Texas from 2011 to 2018 including emergence of ribotype 255. Emerg Microbes Infect. 2020; 9(1):341-347.
PCR ribotypes of Clostridioides difficile across Texas from 2011 to 2018 including emergence of ribotype 255.
Carlson TJ, Endres BT, Le Pham J, Gonzales-Luna AJ, Alnezary FS, Nebo K, Miranda J, Lancaster C, Bass?res E, Begum K, Alam MJ, Reveles KR, Garey KW
Eosinopenia and Binary Toxin Increase Mortality in Hospitalized Patients With Clostridioides difficile Infection. Open Forum Infect Dis. 2020 Jan; 7(1):ofz552.
Eosinopenia and Binary Toxin Increase Mortality in Hospitalized Patients With Clostridioides difficile Infection.
Rashid T, Haghighi F, Hasan I, Bass?res E, Alam MJ, Sharma SV, Lai D, DuPont HL, Garey KW
Activity of Hospital Disinfectants against Vegetative Cells and Spores of Clostridioides difficile Embedded in Biofilms. Antimicrob Agents Chemother. 2019 12 20; 64(1).
Activity of Hospital Disinfectants against Vegetative Cells and Spores of Clostridioides difficile Embedded in Biofilms.
Sofjan AK, Islam MA, Halder K, Kabir ND, Saleh AA, Miranda J, Lancaster C, Begum K, Alam MJ, Garey KW
Molecular epidemiology of toxigenic Clostridioides difficile isolates from hospitalized patients and the hospital environment in Dhaka, Bangladesh. Anaerobe. 2020 Feb; 61:102081.
Molecular epidemiology of toxigenic Clostridioides difficile isolates from hospitalized patients and the hospital environment in Dhaka, Bangladesh.
Alam MJ, McPherson J, Miranda J, Thrall A, Ngo V, Kessinger R, Begum K, Marin M, Garey KW
Molecular epidemiology of Clostridioides difficile in domestic dogs and zoo animals. Anaerobe. 2019 Oct; 59:107-111.
Molecular epidemiology of Clostridioides difficile in domestic dogs and zoo animals.
Islam MA, Kabir ND, Moniruzzaman M, Begum K, Ahmed D, Faruque ASG, Garey KW, Alam MJ
Clostridioides difficile ribotypes isolated from domestic environment and from patients in Bangladesh. Anaerobe. 2019 Apr; 56:88-90.
Clostridioides difficile ribotypes isolated from domestic environment and from patients in Bangladesh.
Endres BT, Begum K, Sun H, Walk ST, Memariani A, Lancaster C, Gonzales-Luna AJ, Dotson KM, Bass?res E, Offiong C, Tupy S, Kuper K, Septimus E, Arafat R, Alam MJ, Zhao Z, Hurdle JG, Savidge TC, Garey KW
Epidemic Clostridioides difficile Ribotype 027 Lineages: Comparisons of Texas Versus Worldwide Strains. Open Forum Infect Dis. 2019 Feb; 6(2):ofz013.
Epidemic Clostridioides difficile Ribotype 027 Lineages: Comparisons of Texas Versus Worldwide Strains.
Endres BT, Dotson KM, Poblete K, McPherson J, Lancaster C, Bass?res E, Memariani A, Arnold S, Tupy S, Carlsen C, Morehead B, Anyatonwu S, Cook C, Begum K, Alam MJ, Garey KW
Infection control and hospital epidemiology
Environmental transmission of Clostridioides difficile ribotype 027 at a long-term care facility; an outbreak investigation guided by whole genome sequencing. Infect Control Hosp Epidemiol. 2018 11; 39(11):1322-1329.
Environmental transmission of Clostridioides difficile ribotype 027 at a long-term care facility; an outbreak investigation guided by whole genome sequencing.
Reveles KR, Dotson KM, Gonzales-Luna A, Surati D, Endres BT, Alam MJ, Garey KW
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Clostridioides (Formerly Clostridium) difficile Infection During Hospitalization Increases the Likelihood of Nonhome Patient Discharge. Clin Infect Dis. 2019 05 17; 68(11):1887-1893.
Clostridioides (Formerly Clostridium) difficile Infection During Hospitalization Increases the Likelihood of Nonhome Patient Discharge.
Sofjan AK, Casey BO, Xu BA, Amadio J, Restrepo A, Alam MJ, Garey KW
Accelerate PhenoTestTM BC Kit Versus Conventional Methods for Identification and Antimicrobial Susceptibility Testing of Gram-Positive Bloodstream Isolates: Potential Implications for Antimicrobial Stewardship. Ann Pharmacother. 2018 08; 52(8):754-762.
Accelerate PhenoTestTM BC Kit Versus Conventional Methods for Identification and Antimicrobial Susceptibility Testing of Gram-Positive Bloodstream Isolates: Potential Implications for Antimicrobial Stewardship.
Ponnada S, Guerrero DM, Jury LA, Nerandzic MM, Cadnum JL, Alam MJ, Donskey CJ
Acquisition of Clostridium difficile Colonization and Infection After Transfer From a Veterans Affairs Hospital to an Affiliated Long-Term Care Facility. Infect Control Hosp Epidemiol. 2017 Sep; 38(9):1070-1076.
Acquisition of Clostridium difficile Colonization and Infection After Transfer From a Veterans Affairs Hospital to an Affiliated Long-Term Care Facility.
Alam MJ, Walk ST, Endres BT, Basseres E, Khaleduzzaman M, Amadio J, Musick WL, Christensen JL, Kuo J, Atmar RL, Garey KW
Community Environmental Contamination of Toxigenic Clostridium difficile. Open Forum Infect Dis. 2017; 4(1):ofx018.
Community Environmental Contamination of Toxigenic Clostridium difficile.
Endres BT, Bass?res E, Alam MJ, Garey KW
Cadazolid for the treatment of Clostridium difficile. Expert Opin Investig Drugs. 2017 Apr; 26(4):509-514.
Cadazolid for the treatment of Clostridium difficile.
Bass?res E, Endres BT, Dotson KM, Alam MJ, Garey KW
Novel antibiotics in development to treat Clostridium difficile infection. Curr Opin Gastroenterol. 2017 01; 33(1):1-7.
Novel antibiotics in development to treat Clostridium difficile infection.
Thabit AK, Alam MJ, Burnham CD, Nicolau DP
Clinical use comparison of a semiautomated PCR with fluorescent ribotyping for typing of Clostridium difficile. Arch Microbiol. 2017 Mar; 199(2):317-323.
Clinical use comparison of a semiautomated PCR with fluorescent ribotyping for typing of Clostridium difficile.
Thabit AK, Alam MJ, Khaleduzzaman M, Garey KW, Nicolau DP
Annals of clinical microbiology and antimicrobials
A pilot study to assess bacterial and toxin reduction in patients with Clostridium difficile infection given fidaxomicin or vancomycin. Ann Clin Microbiol Antimicrob. 2016 Apr 12; 15:22.
A pilot study to assess bacterial and toxin reduction in patients with Clostridium difficile infection given fidaxomicin or vancomycin.
Endres BT, Bass?res E, Khaleduzzaman M, Alam MJ, Chesnel L, Garey KW
Evaluating the Effects of Surotomycin Treatment on Clostridium difficile Toxin A and B Production, Immune Response, and Morphological Changes. Antimicrob Agents Chemother. 2016 06; 60(6):3519-23.
Evaluating the Effects of Surotomycin Treatment on Clostridium difficile Toxin A and B Production, Immune Response, and Morphological Changes.
Bass?res E, Endres BT, Khaleduzzaman M, Miraftabi F, Alam MJ, Vickers RJ, Garey KW
Impact on toxin production and cell morphology in Clostridium difficile by ridinilazole (SMT19969), a novel treatment for C. difficile infection. J Antimicrob Chemother. 2016 May; 71(5):1245-51.
Impact on toxin production and cell morphology in Clostridium difficile by ridinilazole (SMT19969), a novel treatment for C. difficile infection.
Aitken SL, Alam MJ, Khaleduzzaman M, Khaleduzzuman M, Walk ST, Musick WL, Pham VP, Christensen JL, Atmar RL, Xie Y, Garey KW
In the Endemic Setting, Clostridium difficile Ribotype 027 Is Virulent But Not Hypervirulent. Infect Control Hosp Epidemiol. 2015 Nov; 36(11):1318-23.
In the Endemic Setting, Clostridium difficile Ribotype 027 Is Virulent But Not Hypervirulent.
Martinson JN, Broadaway S, Lohman E, Johnson C, Alam MJ, Khaleduzzaman M, Garey KW, Schlackman J, Young VB, Santhosh K, Rao K, Lyons RH, Walk ST
Evaluation of portability and cost of a fluorescent PCR ribotyping protocol for Clostridium difficile epidemiology. J Clin Microbiol. 2015 Apr; 53(4):1192-7.
Evaluation of portability and cost of a fluorescent PCR ribotyping protocol for Clostridium difficile epidemiology.
Investigation of potentially pathogenic Clostridium difficile contamination in household environs. Anaerobe. 2014 Jun; 27:31-3.
Investigation of potentially pathogenic Clostridium difficile contamination in household environs.
Diagnostic microbiology and infectious disease
Comparison of the T2Dx instrument with T2Candida assay and automated blood culture in the detection of Candida species using seeded blood samples. Diagn Microbiol Infect Dis. 2013 Dec; 77(4):324-6.
Comparison of the T2Dx instrument with T2Candida assay and automated blood culture in the detection of Candida species using seeded blood samples.
Beyda ND, Chuang SH, Alam MJ, Shah DN, Ng TM, McCaskey L, Garey KW
Treatment of Candida famata bloodstream infections: case series and review of the literature. J Antimicrob Chemother. 2013 Feb; 68(2):438-43.
Treatment of Candida famata bloodstream infections: case series and review of the literature.
Inhibition of biofilm formation by esomeprazole in Pseudomonas aeruginosa and Staphylococcus aureus. Antimicrob Agents Chemother. 2012 Aug; 56(8):4360-4.
Inhibition of biofilm formation by esomeprazole in Pseudomonas aeruginosa and Staphylococcus aureus.