Alam, Jahangir
first name: Jahangir
last name: Alam
coauthor of: Begum, Khurshida
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full name: Jahangir Alam
has faculty rank: Associate Professor
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selected publications: Authorship 7459
selected publications: Authorship 7460
selected publications: Authorship 7461
selected publications: Authorship 7462
selected publications: Authorship 7463
selected publications: Authorship 7466
selected publications: Authorship 7464
selected publications: Authorship 7465
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selected publications: Authorship 7469
selected publications: Authorship 7470
selected publications: Authorship 7471
selected publications: Authorship 7472
selected publications: Authorship 7473
selected publications: Authorship 7477
selected publications: Authorship 7474
selected publications: Authorship 7475
selected publications: Authorship 7476
selected publications: Authorship 7478
selected publications: Authorship 7479
selected publications: Authorship 7480
selected publications: Authorship 7482
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selected publications: Authorship 7484
selected publications: Authorship 7487
selected publications: Authorship 7485
selected publications: Authorship 7486
selected publications: Authorship 7488
selected publications: Authorship 7489
selected publications: Authorship 7490
selected publications: Authorship 7491
selected publications: Authorship 7492
selected publications: Authorship 7493
selected publications: Authorship 7494
research areas: Clostridium Infections
research areas: Ribotyping
research areas: Anti-Bacterial Agents
research areas: Feces
research areas: Environmental Microbiology
mailing address: https://profilesrns.times.uh.edu/profile/173815
positions: Associate Professor
preferred title: Associate Professor

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Environmental Microbiology
MeSH DescriptorUI: D004783
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number of authors: 5
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A novel method for imaging the pharmacological effects of antibiotic treatment on Clostridium difficile.
PubMed Identifier: 27108094
author list: Endres BT, Bassères E, Memariani A, Chang L, Alam MJ, Vickers RJ, Kakadiaris IA, Garey KW
published in: Anaerobe
information resource reference: A novel method for imaging the pharmacological effects of antibiotic treatment on Clostridium difficile. Anaerobe. 2016 Aug; 40:10-4.
journal title abbreviation: Anaerobe
publication date: 2016-04-21T00:00:00
year: 2016
type: Academic Article
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https://profilesrns.times.uh.edu/profile/173815
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address line 1: 4800 Calhoun Rd
city: Houston
postal code: 77004
state or province: TX

Electrical and Computer Engineering
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Pharmaceutical Health Outcomes and Policy
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Pharmacy Practice and Translational Research
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Psychology
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Engineering
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Hu, Chenlin
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Bassères, Eugénie
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Anti-Bacterial Agents
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MeSH semantic group name: Chemicals & Drugs
number of authors: 41
number of publications: 183
uniqueness weight: 0.821289
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Chang, Long
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Beyda, Nicholas
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Tam, Vincent
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Begum, Khurshida
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has faculty rank: Lecturer
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Feces
MeSH DescriptorUI: D005243
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number of authors: 11
number of publications: 26
uniqueness weight: 0.971765
type: Concept

Psychology
type: Division
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Zvolensky, Michael
first name: Michael
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College of Pharmacy
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A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment.
PubMed Identifier: 28570548
author list: Endres B, Bass?res E, Rashid T, Chang L, Alam MJ, Garey KW
published in: Journal of visualized experiments : JoVE
information resource reference: A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment. J Vis Exp. 2017 05 25; (123).
journal title abbreviation: J Vis Exp
publication date: 2017-05-25T00:00:00
year: 2017
type: Academic Article
type: Article
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Clostridium Infections
MeSH DescriptorUI: D003015
MeSH semantic group name: Disorders
number of authors: 8
number of publications: 56
uniqueness weight: 0.937438
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University of Houston
type: Organization

Authorship 7451
type: Authorship
author rank in publication: 6
linked author: Alam, Jahangir
linked information resource: Phase I trial comparing bile acid and short-chain fatty acid alterations in stool collected from human subjects treated with omadacycline or vancomycin.

Authorship 7452
type: Authorship
author rank in publication: 3
linked author: Alam, Jahangir
linked information resource: A quantitative PCR to detect non-toxigenic Clostridioides difficile.

Authorship 7453
type: Authorship
author rank in publication: 4
linked author: Alam, Jahangir
linked information resource: Antibacterial activity of ibezapolstat against antimicrobial-resistant clinical strains of Clostridioides difficile.

Authorship 7454
type: Authorship
author rank in publication: 8
linked author: Alam, Jahangir
linked information resource: Comparison of Risk Stratification Approaches to Identify Patients with Clostridioides difficile Infection at Risk for Multidrug-Resistant Organism Gut Microbiota Colonization.

Authorship 7455
type: Authorship
author rank in publication: 9
linked author: Alam, Jahangir
linked information resource: The Novel DNA Binding Mechanism of Ridinilazole, a Precision Clostridiodes difficile Antibiotic.

Authorship 7456
type: Authorship
author rank in publication: 8
linked author: Alam, Jahangir
linked information resource: Fusobacteria behaving badly: Masquerading strains of strictly anaerobic Escherichiacoli misidentified due to the deletion of the hemB gene.

Authorship 7457
type: Authorship
author rank in publication: 10
linked author: Alam, Jahangir
linked information resource: Isolation and characterisation of carbapenem-resistant Pseudomonas aeruginosa from hospital environments in tertiary care hospitals in Dhaka, Bangladesh.

Authorship 7458
type: Authorship
author rank in publication: 8
linked author: Alam, Jahangir
linked information resource: Association of Antibiotic Resistance Traits in Uropathogenic Escherichia coli (UPEC) Isolates.

Authorship 7459
type: Authorship
author rank in publication: 5
linked author: Alam, Jahangir
linked information resource: Draft genome sequence data of a clinical Enterococcus faecalis isolate SHH039 from a patient with cholecystitis from a tertiary care hospital in Sabah, Malaysia.

Authorship 7460
type: Authorship
author rank in publication: 5
linked author: Alam, Jahangir
linked information resource: Comparative clinical outcomes evaluation of hospitalized patients infected with Clostridioides difficile ribotype 106 vs. other toxigenic strains.

Authorship 7461
type: Authorship
author rank in publication: 9
linked author: Alam, Jahangir
linked information resource: Reduced Susceptibility to Metronidazole Is Associated With Initial Clinical Failure in Clostridioides difficile Infection.

Authorship 7462
type: Authorship
author rank in publication: 7
linked author: Alam, Jahangir
linked information resource: Systems biology evaluation of refractory Clostridioides difficile infection including multiple failures of fecal microbiota transplantation.

Authorship 7463
type: Authorship
author rank in publication: 8
linked author: Alam, Jahangir
linked information resource: Visualization of fidaxomicin association with the exosporium layer of Clostridioides difficile spores.

Authorship 7464
type: Authorship
author rank in publication: 8
linked author: Alam, Jahangir
linked information resource: Assessment of Kidney Injury as a Severity Criteria for Clostridioides Difficile Infection.

Authorship 7465
type: Authorship
author rank in publication: 5
linked author: Alam, Jahangir
linked information resource: Whole genome sequencing data of a clinical Enterococcus gallinarum strain EGR748 from Sabah, Malaysia.

Authorship 7466
type: Authorship
author rank in publication: 12
linked author: Alam, Jahangir
linked information resource: https://profilesrns.times.uh.edu/profile/329046

Authorship 7467
type: Authorship
author rank in publication: 8
linked author: Alam, Jahangir
linked information resource: In vitro activity of eravacycline against common ribotypes of Clostridioides difficile.

Authorship 7468
type: Authorship
author rank in publication: 10
linked author: Alam, Jahangir
linked information resource: In Vitro Activity of Omadacycline, a New Tetracycline Analog, and Comparators against Clostridioides difficile.

Authorship 7469
type: Authorship
author rank in publication: 11
linked author: Alam, Jahangir
linked information resource: PCR ribotypes of Clostridioides difficile across Texas from 2011 to 2018 including emergence of ribotype 255.

Authorship 7470
type: Authorship
author rank in publication: 11
linked author: Alam, Jahangir
linked information resource: Eosinopenia and Binary Toxin Increase Mortality in Hospitalized Patients With Clostridioides difficile Infection.

Authorship 7471
type: Authorship
author rank in publication: 5
linked author: Alam, Jahangir
linked information resource: Activity of Hospital Disinfectants against Vegetative Cells and Spores of Clostridioides difficile Embedded in Biofilms.

Authorship 7472
type: Authorship
author rank in publication: 9
linked author: Alam, Jahangir
linked information resource: Molecular epidemiology of toxigenic Clostridioides difficile isolates from hospitalized patients and the hospital environment in Dhaka, Bangladesh.

Authorship 7473
type: Authorship
author rank in publication: 1
linked author: Alam, Jahangir
linked information resource: Molecular epidemiology of Clostridioides difficile in domestic dogs and zoo animals.

Authorship 7474
type: Authorship
author rank in publication: 8
linked author: Alam, Jahangir
linked information resource: Clostridioides difficile ribotypes isolated from domestic environment and from patients in Bangladesh.

Authorship 7475
type: Authorship
author rank in publication: 15
linked author: Alam, Jahangir
linked information resource: Epidemic Clostridioides difficile Ribotype 027 Lineages: Comparisons of Texas Versus Worldwide Strains.

Authorship 7476
type: Authorship
author rank in publication: 15
linked author: Alam, Jahangir
linked information resource: Environmental transmission of Clostridioides difficile ribotype 027 at a long-term care facility; an outbreak investigation guided by whole genome sequencing.

Authorship 7477
type: Authorship
author rank in publication: 6
linked author: Alam, Jahangir
linked information resource: Clostridioides (Formerly Clostridium) difficile Infection During Hospitalization Increases the Likelihood of Nonhome Patient Discharge.

Authorship 7478
type: Authorship
author rank in publication: 6
linked author: Alam, Jahangir
linked information resource: https://profilesrns.times.uh.edu/profile/329058

Authorship 7479
type: Authorship
author rank in publication: 6
linked author: Alam, Jahangir
linked information resource: Acquisition of Clostridium difficile Colonization and Infection After Transfer From a Veterans Affairs Hospital to an Affiliated Long-Term Care Facility.

Authorship 7480
type: Authorship
author rank in publication: 5
linked author: Alam, Jahangir
linked information resource: A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment.

Authorship 7481
type: Authorship
author rank in publication: 1
linked author: Alam, Jahangir
linked information resource: Community Environmental Contamination of Toxigenic Clostridium difficile.

Authorship 7482
type: Authorship
author rank in publication: 3
linked author: Alam, Jahangir
linked information resource: Cadazolid for the treatment of Clostridium difficile.

Authorship 7483
type: Authorship
author rank in publication: 4
linked author: Alam, Jahangir
linked information resource: Novel antibiotics in development to treat Clostridium difficile infection.

Authorship 7484
type: Authorship
author rank in publication: 2
linked author: Alam, Jahangir
linked information resource: Clinical use comparison of a semiautomated PCR with fluorescent ribotyping for typing of Clostridium difficile.

Authorship 7485
type: Authorship
author rank in publication: 5
linked author: Alam, Jahangir
linked information resource: A novel method for imaging the pharmacological effects of antibiotic treatment on Clostridium difficile.

Authorship 7486
type: Authorship
author rank in publication: 2
linked author: Alam, Jahangir
linked information resource: A pilot study to assess bacterial and toxin reduction in patients with Clostridium difficile infection given fidaxomicin or vancomycin.

Authorship 7487
type: Authorship
author rank in publication: 4
linked author: Alam, Jahangir
linked information resource: Evaluating the Effects of Surotomycin Treatment on Clostridium difficile Toxin A and B Production, Immune Response, and Morphological Changes.

Authorship 7488
type: Authorship
author rank in publication: 5
linked author: Alam, Jahangir
linked information resource: Impact on toxin production and cell morphology in Clostridium difficile by ridinilazole (SMT19969), a novel treatment for C. difficile infection.

Authorship 7489
type: Authorship
author rank in publication: 2
linked author: Alam, Jahangir
linked information resource: In the Endemic Setting, Clostridium difficile Ribotype 027 Is Virulent But Not Hypervirulent.

Authorship 7490
type: Authorship
author rank in publication: 5
linked author: Alam, Jahangir
linked information resource: Evaluation of portability and cost of a fluorescent PCR ribotyping protocol for Clostridium difficile epidemiology.

Authorship 7491
type: Authorship
author rank in publication: 1
linked author: Alam, Jahangir
linked information resource: Investigation of potentially pathogenic Clostridium difficile contamination in household environs.

Authorship 7492
type: Authorship
author rank in publication: 2
linked author: Alam, Jahangir
linked information resource: Comparison of the T2Dx instrument with T2Candida assay and automated blood culture in the detection of Candida species using seeded blood samples.

Authorship 7493
type: Authorship
author rank in publication: 3
linked author: Alam, Jahangir
linked information resource: Treatment of Candida famata bloodstream infections: case series and review of the literature.

Authorship 7494
type: Authorship
author rank in publication: 3
linked author: Alam, Jahangir
linked information resource: Inhibition of biofilm formation by esomeprazole in Pseudomonas aeruginosa and Staphylococcus aureus.

Phase I trial comparing bile acid and short-chain fatty acid alterations in stool collected from human subjects treated with omadacycline or vancomycin.
PubMed Identifier: 39819014
author list: Jo J, Hu C, Horvath TD, Haidacher SJ, Begum K, Alam MJ, Garey KW
published in: Antimicrobial agents and chemotherapy
information resource reference: Phase I trial comparing bile acid and short-chain fatty acid alterations in stool collected from human subjects treated with omadacycline or vancomycin. Antimicrob Agents Chemother. 2025 Feb 13; 69(2):e0125124.
journal title abbreviation: Antimicrob Agents Chemother
publication date: 2025-01-17T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

A quantitative PCR to detect non-toxigenic Clostridioides difficile.
PubMed Identifier: 39660903
author list: Begum K, Chua HC, Alam MJ, Garey KW, Jo J
published in: Microbiology spectrum
information resource reference: A quantitative PCR to detect non-toxigenic Clostridioides difficile. Microbiol Spectr. 2025 Jan 07; 13(1):e0160824.
journal title abbreviation: Microbiol Spectr
publication date: 2024-12-11T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Antibacterial activity of ibezapolstat against antimicrobial-resistant clinical strains of Clostridioides difficile.
PubMed Identifier: 38364016
author list: Bass?res E, Eubank TA, Begum K, Alam MJ, Jo J, Le TM, Lancaster CK, Gonzales-Luna AJ, Garey KW
published in: Antimicrobial agents and chemotherapy
information resource reference: Antibacterial activity of ibezapolstat against antimicrobial-resistant clinical strains of Clostridioides difficile. Antimicrob Agents Chemother. 2024 03 06; 68(3):e0162123.
journal title abbreviation: Antimicrob Agents Chemother
publication date: 2024-02-16T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Comparison of Risk Stratification Approaches to Identify Patients with Clostridioides difficile Infection at Risk for Multidrug-Resistant Organism Gut Microbiota Colonization.
PubMed Identifier: 37436677
author list: Zasowski EJ, Ali M, Anugo A, Ibragimova N, Dotson KM, Endres BT, Begum K, Alam MJ, Garey KW
published in: Infectious diseases and therapy
information resource reference: Comparison of Risk Stratification Approaches to Identify Patients with Clostridioides difficile Infection at Risk for Multidrug-Resistant Organism Gut Microbiota Colonization. Infect Dis Ther. 2023 Aug; 12(8):2005-2015.
journal title abbreviation: Infect Dis Ther
publication date: 2023-07-12T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

The Novel DNA Binding Mechanism of Ridinilazole, a Precision Clostridiodes difficile Antibiotic.
PubMed Identifier: 37093023
author list: Mason CS, Avis T, Hu C, Nagalingam N, Mudaliar M, Coward C, Begum K, Gajewski K, Alam MJ, Bass?res E, Moss S, Reich S, Duperchy E, Fox KR, Garey KW, Powell DJ
published in: Antimicrobial agents and chemotherapy
information resource reference: The Novel DNA Binding Mechanism of Ridinilazole, a Precision Clostridiodes difficile Antibiotic. Antimicrob Agents Chemother. 2023 05 17; 67(5):e0156322.
journal title abbreviation: Antimicrob Agents Chemother
publication date: 2023-04-24T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Fusobacteria behaving badly: Masquerading strains of strictly anaerobic Escherichiacoli misidentified due to the deletion of the hemB gene.
PubMed Identifier: 36580991
author list: Endres BT, Basseres E, Citron DM, Tyrrell KL, Begum K, Lancaster C, Warren YA, Alam MJ, Garey KW, Goldstein EJC
published in: Anaerobe
information resource reference: Fusobacteria behaving badly: Masquerading strains of strictly anaerobic Escherichiacoli misidentified due to the deletion of the hemB gene. Anaerobe. 2023 Feb; 79:102682.
journal title abbreviation: Anaerobe
publication date: 2022-12-27T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Isolation and characterisation of carbapenem-resistant Pseudomonas aeruginosa from hospital environments in tertiary care hospitals in Dhaka, Bangladesh.
PubMed Identifier: 35447383
author list: Saha K, Kabir ND, Islam MR, Amin MB, Hoque KI, Halder K, Saleh AA, Parvez MAK, Begum K, Alam MJ, Islam MA
published in: Journal of global antimicrobial resistance
information resource reference: Isolation and characterisation of carbapenem-resistant Pseudomonas aeruginosa from hospital environments in tertiary care hospitals in Dhaka, Bangladesh. J Glob Antimicrob Resist. 2022 09; 30:31-37.
journal title abbreviation: J Glob Antimicrob Resist
publication date: 2022-04-18T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Association of Antibiotic Resistance Traits in Uropathogenic Escherichia coli (UPEC) Isolates.
PubMed Identifier: 35340918
author list: Rahman MM, Hossain MMK, Rubaya R, Halder J, Karim ME, Bhuiya AA, Khatun A, Alam J
published in: The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale
information resource reference: Association of Antibiotic Resistance Traits in Uropathogenic Escherichia coli (UPEC) Isolates. Can J Infect Dis Med Microbiol. 2022; 2022:4251486.
journal title abbreviation: Can J Infect Dis Med Microbiol
publication date: 2022-03-16T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Draft genome sequence data of a clinical Enterococcus faecalis isolate SHH039 from a patient with cholecystitis from a tertiary care hospital in Sabah, Malaysia.
PubMed Identifier: 35295870
author list: Mastor NNI, Subbiah VK, Bakar WNWA, Begum K, Alam MJ, Hoque MZ
published in: Data in brief
information resource reference: Draft genome sequence data of a clinical Enterococcus faecalis isolate SHH039 from a patient with cholecystitis from a tertiary care hospital in Sabah, Malaysia. Data Brief. 2022 Apr; 41:108019.
journal title abbreviation: Data Brief
publication date: 2022-03-06T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Comparative clinical outcomes evaluation of hospitalized patients infected with Clostridioides difficile ribotype 106 vs. other toxigenic strains.
PubMed Identifier: 34461273
author list: Almutairi MS, Gonzales-Luna AJ, Alnezary FS, Fallatah SB, Alam MJ, Begum K, Garey KW
published in: Anaerobe
information resource reference: Comparative clinical outcomes evaluation of hospitalized patients infected with Clostridioides difficile ribotype 106 vs. other toxigenic strains. Anaerobe. 2021 Dec; 72:102440.
journal title abbreviation: Anaerobe
publication date: 2021-08-27T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Reduced Susceptibility to Metronidazole Is Associated With Initial Clinical Failure in Clostridioides difficile Infection.
PubMed Identifier: 34381844
author list: Gonzales-Luna AJ, Olaitan AO, Shen WJ, Deshpande A, Carlson TJ, Dotson KM, Lancaster C, Begum K, Alam MJ, Hurdle JG, Garey KW
published in: Open forum infectious diseases
information resource reference: Reduced Susceptibility to Metronidazole Is Associated With Initial Clinical Failure in Clostridioides difficile Infection. Open Forum Infect Dis. 2021 Aug; 8(8):ofab365.
journal title abbreviation: Open Forum Infect Dis
publication date: 2021-07-08T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Systems biology evaluation of refractory Clostridioides difficile infection including multiple failures of fecal microbiota transplantation.
PubMed Identifier: 34044101
author list: Gonzales-Luna AJ, Spinler JK, Oezguen N, Khan MAW, Danhof HA, Endres BT, Alam MJ, Begum K, Lancaster C, Costa GP, Savidge TC, Hurdle JG, Britton R, Garey KW
published in: Anaerobe
information resource reference: Systems biology evaluation of refractory Clostridioides difficile infection including multiple failures of fecal microbiota transplantation. Anaerobe. 2021 Aug; 70:102387.
journal title abbreviation: Anaerobe
publication date: 2021-05-24T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Visualization of fidaxomicin association with the exosporium layer of Clostridioides difficile spores.
PubMed Identifier: 33640461
author list: Bass?res E, Endres BT, Montes-Bravo N, P?rez-Soto N, Rashid T, Lancaster C, Begum K, Alam MJ, Paredes-Sabja D, Garey KW
published in: Anaerobe
information resource reference: Visualization of fidaxomicin association with the exosporium layer of Clostridioides difficile spores. Anaerobe. 2021 Jun; 69:102352.
journal title abbreviation: Anaerobe
publication date: 2021-02-25T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Assessment of Kidney Injury as a Severity Criteria for Clostridioides Difficile Infection.
PubMed Identifier: 33209956
author list: Carlson TJ, Gonzales-Luna AJ, Nebo K, Chan HY, Tran NT, Antony S, Lancaster C, Alam MJ, Begum K, Garey KW
published in: Open forum infectious diseases
information resource reference: Assessment of Kidney Injury as a Severity Criteria for Clostridioides Difficile Infection. Open Forum Infect Dis. 2020 Nov; 7(11):ofaa476.
journal title abbreviation: Open Forum Infect Dis
publication date: 2020-10-07T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Whole genome sequencing data of a clinical Enterococcus gallinarum strain EGR748 from Sabah, Malaysia.
PubMed Identifier: 33102652
author list: Mastor NN, Subbiah VK, Bakar WNWA, Begum K, Alam MJ, Hoque MZ
published in: Data in brief
information resource reference: Whole genome sequencing data of a clinical Enterococcus gallinarum strain EGR748 from Sabah, Malaysia. Data Brief. 2020 Dec; 33:106370.
journal title abbreviation: Data Brief
publication date: 2020-10-02T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

https://profilesrns.times.uh.edu/profile/329046
PubMed Identifier: 32892222
author list: Garey KW, Begum K, Lancaster C, Gonzales-Luna A, Bui D, Mercier J, Seng Yue C, Ducharme MP, Hu M, Vince B, Silverman MH, Alam MJ, Kankam M
published in: The Journal of antimicrobial chemotherapy
information resource reference: A randomized, double-blind, placebo-controlled, single and multiple ascending dose Phase 1 study to determine the safety, pharmacokinetics and food and faecal microbiome effects of ibezapolstat administered orally to healthy subjects. J Antimicrob Chemother. 2020 12 01; 75(12):3635-3643.
journal title abbreviation: J Antimicrob Chemother
publication date: 2020-12-01T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource
label: A randomized, double-blind, placebo-controlled, single and multiple ascending dose Phase 1 study to determine the safety, pharmacokinetics and food and faecal microbiome effects of ibezapolstat administered orally to healthy subjects.

In vitro activity of eravacycline against common ribotypes of Clostridioides difficile.
PubMed Identifier: 32719870
author list: Bass?res E, Begum K, Lancaster C, Gonzales-Luna AJ, Carlson TJ, Miranda J, Rashid T, Alam MJ, Eyre DW, Wilcox MH, Garey KW
published in: The Journal of antimicrobial chemotherapy
information resource reference: In vitro activity of eravacycline against common ribotypes of Clostridioides difficile. J Antimicrob Chemother. 2020 10 01; 75(10):2879-2884.
journal title abbreviation: J Antimicrob Chemother
publication date: 2020-10-01T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

In Vitro Activity of Omadacycline, a New Tetracycline Analog, and Comparators against Clostridioides difficile.
PubMed Identifier: 32513796
author list: Begum K, Bass?res E, Miranda J, Lancaster C, Gonzales-Luna AJ, Carlson TJ, Rashid T, Eyre DW, Wilcox MH, Alam MJ, Garey KW
published in: Antimicrobial agents and chemotherapy
information resource reference: In Vitro Activity of Omadacycline, a New Tetracycline Analog, and Comparators against Clostridioides difficile. Antimicrob Agents Chemother. 2020 07 22; 64(8).
journal title abbreviation: Antimicrob Agents Chemother
publication date: 2020-07-22T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

PCR ribotypes of Clostridioides difficile across Texas from 2011 to 2018 including emergence of ribotype 255.
PubMed Identifier: 32037964
author list: Gonzales-Luna AJ, Carlson TJ, Dotson KM, Poblete K, Costa G, Miranda J, Lancaster C, Walk ST, Tupy S, Begum K, Alam MJ, Garey KW
published in: Emerging microbes & infections
information resource reference: PCR ribotypes of Clostridioides difficile across Texas from 2011 to 2018 including emergence of ribotype 255. Emerg Microbes Infect. 2020; 9(1):341-347.
journal title abbreviation: Emerg Microbes Infect
publication date: 2020-02-10T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Eosinopenia and Binary Toxin Increase Mortality in Hospitalized Patients With Clostridioides difficile Infection.
PubMed Identifier: 31993458
author list: Carlson TJ, Endres BT, Le Pham J, Gonzales-Luna AJ, Alnezary FS, Nebo K, Miranda J, Lancaster C, Bass?res E, Begum K, Alam MJ, Reveles KR, Garey KW
published in: Open forum infectious diseases
information resource reference: Eosinopenia and Binary Toxin Increase Mortality in Hospitalized Patients With Clostridioides difficile Infection. Open Forum Infect Dis. 2020 Jan; 7(1):ofz552.
journal title abbreviation: Open Forum Infect Dis
publication date: 2020-01-04T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Activity of Hospital Disinfectants against Vegetative Cells and Spores of Clostridioides difficile Embedded in Biofilms.
PubMed Identifier: 31611365
author list: Rashid T, Haghighi F, Hasan I, Bass?res E, Alam MJ, Sharma SV, Lai D, DuPont HL, Garey KW
published in: Antimicrobial agents and chemotherapy
information resource reference: Activity of Hospital Disinfectants against Vegetative Cells and Spores of Clostridioides difficile Embedded in Biofilms. Antimicrob Agents Chemother. 2019 12 20; 64(1).
journal title abbreviation: Antimicrob Agents Chemother
publication date: 2019-12-20T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Molecular epidemiology of toxigenic Clostridioides difficile isolates from hospitalized patients and the hospital environment in Dhaka, Bangladesh.
PubMed Identifier: 31356958
author list: Sofjan AK, Islam MA, Halder K, Kabir ND, Saleh AA, Miranda J, Lancaster C, Begum K, Alam MJ, Garey KW
published in: Anaerobe
information resource reference: Molecular epidemiology of toxigenic Clostridioides difficile isolates from hospitalized patients and the hospital environment in Dhaka, Bangladesh. Anaerobe. 2020 Feb; 61:102081.
journal title abbreviation: Anaerobe
publication date: 2019-07-26T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Molecular epidemiology of Clostridioides difficile in domestic dogs and zoo animals.
PubMed Identifier: 31207298
author list: Alam MJ, McPherson J, Miranda J, Thrall A, Ngo V, Kessinger R, Begum K, Marin M, Garey KW
published in: Anaerobe
information resource reference: Molecular epidemiology of Clostridioides difficile in domestic dogs and zoo animals. Anaerobe. 2019 Oct; 59:107-111.
journal title abbreviation: Anaerobe
publication date: 2019-06-15T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Clostridioides difficile ribotypes isolated from domestic environment and from patients in Bangladesh.
PubMed Identifier: 30794875
author list: Islam MA, Kabir ND, Moniruzzaman M, Begum K, Ahmed D, Faruque ASG, Garey KW, Alam MJ
published in: Anaerobe
information resource reference: Clostridioides difficile ribotypes isolated from domestic environment and from patients in Bangladesh. Anaerobe. 2019 Apr; 56:88-90.
journal title abbreviation: Anaerobe
publication date: 2019-02-19T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Epidemic Clostridioides difficile Ribotype 027 Lineages: Comparisons of Texas Versus Worldwide Strains.
PubMed Identifier: 30793006
author list: Endres BT, Begum K, Sun H, Walk ST, Memariani A, Lancaster C, Gonzales-Luna AJ, Dotson KM, Bass?res E, Offiong C, Tupy S, Kuper K, Septimus E, Arafat R, Alam MJ, Zhao Z, Hurdle JG, Savidge TC, Garey KW
published in: Open forum infectious diseases
information resource reference: Epidemic Clostridioides difficile Ribotype 027 Lineages: Comparisons of Texas Versus Worldwide Strains. Open Forum Infect Dis. 2019 Feb; 6(2):ofz013.
journal title abbreviation: Open Forum Infect Dis
publication date: 2019-02-09T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Environmental transmission of Clostridioides difficile ribotype 027 at a long-term care facility; an outbreak investigation guided by whole genome sequencing.
PubMed Identifier: 30253813
author list: Endres BT, Dotson KM, Poblete K, McPherson J, Lancaster C, Bass?res E, Memariani A, Arnold S, Tupy S, Carlsen C, Morehead B, Anyatonwu S, Cook C, Begum K, Alam MJ, Garey KW
published in: Infection control and hospital epidemiology
information resource reference: Environmental transmission of Clostridioides difficile ribotype 027 at a long-term care facility; an outbreak investigation guided by whole genome sequencing. Infect Control Hosp Epidemiol. 2018 11; 39(11):1322-1329.
journal title abbreviation: Infect Control Hosp Epidemiol
publication date: 2018-09-26T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Clostridioides (Formerly Clostridium) difficile Infection During Hospitalization Increases the Likelihood of Nonhome Patient Discharge.
PubMed Identifier: 30204878
author list: Reveles KR, Dotson KM, Gonzales-Luna A, Surati D, Endres BT, Alam MJ, Garey KW
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Clostridioides (Formerly Clostridium) difficile Infection During Hospitalization Increases the Likelihood of Nonhome Patient Discharge. Clin Infect Dis. 2019 05 17; 68(11):1887-1893.
journal title abbreviation: Clin Infect Dis
publication date: 2019-05-17T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

https://profilesrns.times.uh.edu/profile/329058
PubMed Identifier: 29557208
author list: Sofjan AK, Casey BO, Xu BA, Amadio J, Restrepo A, Alam MJ, Garey KW
published in: The Annals of pharmacotherapy
information resource reference: Accelerate PhenoTestTM BC Kit Versus Conventional Methods for Identification and Antimicrobial Susceptibility Testing of Gram-Positive Bloodstream Isolates: Potential Implications for Antimicrobial Stewardship. Ann Pharmacother. 2018 08; 52(8):754-762.
journal title abbreviation: Ann Pharmacother
publication date: 2018-03-20T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Accelerate PhenoTestTM BC Kit Versus Conventional Methods for Identification and Antimicrobial Susceptibility Testing of Gram-Positive Bloodstream Isolates: Potential Implications for Antimicrobial Stewardship.

Acquisition of Clostridium difficile Colonization and Infection After Transfer From a Veterans Affairs Hospital to an Affiliated Long-Term Care Facility.
PubMed Identifier: 28693636
author list: Ponnada S, Guerrero DM, Jury LA, Nerandzic MM, Cadnum JL, Alam MJ, Donskey CJ
published in: Infection control and hospital epidemiology
information resource reference: Acquisition of Clostridium difficile Colonization and Infection After Transfer From a Veterans Affairs Hospital to an Affiliated Long-Term Care Facility. Infect Control Hosp Epidemiol. 2017 Sep; 38(9):1070-1076.
journal title abbreviation: Infect Control Hosp Epidemiol
publication date: 2017-07-11T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Community Environmental Contamination of Toxigenic Clostridium difficile.
PubMed Identifier: 28480289
author list: Alam MJ, Walk ST, Endres BT, Basseres E, Khaleduzzaman M, Amadio J, Musick WL, Christensen JL, Kuo J, Atmar RL, Garey KW
published in: Open forum infectious diseases
information resource reference: Community Environmental Contamination of Toxigenic Clostridium difficile. Open Forum Infect Dis. 2017; 4(1):ofx018.
journal title abbreviation: Open Forum Infect Dis
publication date: 2017-02-10T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Cadazolid for the treatment of Clostridium difficile.
PubMed Identifier: 28286992
author list: Endres BT, Bass?res E, Alam MJ, Garey KW
published in: Expert opinion on investigational drugs
information resource reference: Cadazolid for the treatment of Clostridium difficile. Expert Opin Investig Drugs. 2017 Apr; 26(4):509-514.
journal title abbreviation: Expert Opin Investig Drugs
publication date: 2017-04-01T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Novel antibiotics in development to treat Clostridium difficile infection.
PubMed Identifier: 28134686
author list: Bass?res E, Endres BT, Dotson KM, Alam MJ, Garey KW
published in: Current opinion in gastroenterology
information resource reference: Novel antibiotics in development to treat Clostridium difficile infection. Curr Opin Gastroenterol. 2017 01; 33(1):1-7.
journal title abbreviation: Curr Opin Gastroenterol
publication date: 2017-01-01T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Clinical use comparison of a semiautomated PCR with fluorescent ribotyping for typing of Clostridium difficile.
PubMed Identifier: 27730251
author list: Thabit AK, Alam MJ, Burnham CD, Nicolau DP
published in: Archives of microbiology
information resource reference: Clinical use comparison of a semiautomated PCR with fluorescent ribotyping for typing of Clostridium difficile. Arch Microbiol. 2017 Mar; 199(2):317-323.
journal title abbreviation: Arch Microbiol
publication date: 2016-10-11T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

A pilot study to assess bacterial and toxin reduction in patients with Clostridium difficile infection given fidaxomicin or vancomycin.
PubMed Identifier: 27071986
author list: Thabit AK, Alam MJ, Khaleduzzaman M, Garey KW, Nicolau DP
published in: Annals of clinical microbiology and antimicrobials
information resource reference: A pilot study to assess bacterial and toxin reduction in patients with Clostridium difficile infection given fidaxomicin or vancomycin. Ann Clin Microbiol Antimicrob. 2016 Apr 12; 15:22.
journal title abbreviation: Ann Clin Microbiol Antimicrob
publication date: 2016-04-12T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Evaluating the Effects of Surotomycin Treatment on Clostridium difficile Toxin A and B Production, Immune Response, and Morphological Changes.
PubMed Identifier: 27021314
author list: Endres BT, Bass?res E, Khaleduzzaman M, Alam MJ, Chesnel L, Garey KW
published in: Antimicrobial agents and chemotherapy
information resource reference: Evaluating the Effects of Surotomycin Treatment on Clostridium difficile Toxin A and B Production, Immune Response, and Morphological Changes. Antimicrob Agents Chemother. 2016 06; 60(6):3519-23.
journal title abbreviation: Antimicrob Agents Chemother
publication date: 2016-05-23T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Impact on toxin production and cell morphology in Clostridium difficile by ridinilazole (SMT19969), a novel treatment for C. difficile infection.
PubMed Identifier: 26895772
author list: Bass?res E, Endres BT, Khaleduzzaman M, Miraftabi F, Alam MJ, Vickers RJ, Garey KW
published in: The Journal of antimicrobial chemotherapy
information resource reference: Impact on toxin production and cell morphology in Clostridium difficile by ridinilazole (SMT19969), a novel treatment for C. difficile infection. J Antimicrob Chemother. 2016 May; 71(5):1245-51.
journal title abbreviation: J Antimicrob Chemother
publication date: 2016-02-18T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

In the Endemic Setting, Clostridium difficile Ribotype 027 Is Virulent But Not Hypervirulent.
PubMed Identifier: 26288985
author list: Aitken SL, Alam MJ, Khaleduzzaman M, Khaleduzzuman M, Walk ST, Musick WL, Pham VP, Christensen JL, Atmar RL, Xie Y, Garey KW
published in: Infection control and hospital epidemiology
information resource reference: In the Endemic Setting, Clostridium difficile Ribotype 027 Is Virulent But Not Hypervirulent. Infect Control Hosp Epidemiol. 2015 Nov; 36(11):1318-23.
journal title abbreviation: Infect Control Hosp Epidemiol
publication date: 2015-08-20T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Evaluation of portability and cost of a fluorescent PCR ribotyping protocol for Clostridium difficile epidemiology.
PubMed Identifier: 25631804
author list: Martinson JN, Broadaway S, Lohman E, Johnson C, Alam MJ, Khaleduzzaman M, Garey KW, Schlackman J, Young VB, Santhosh K, Rao K, Lyons RH, Walk ST
published in: Journal of clinical microbiology
information resource reference: Evaluation of portability and cost of a fluorescent PCR ribotyping protocol for Clostridium difficile epidemiology. J Clin Microbiol. 2015 Apr; 53(4):1192-7.
journal title abbreviation: J Clin Microbiol
publication date: 2015-01-28T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Investigation of potentially pathogenic Clostridium difficile contamination in household environs.
PubMed Identifier: 24657158
author list: Alam MJ, Anu A, Walk ST, Garey KW
published in: Anaerobe
information resource reference: Investigation of potentially pathogenic Clostridium difficile contamination in household environs. Anaerobe. 2014 Jun; 27:31-3.
journal title abbreviation: Anaerobe
publication date: 2014-03-19T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Comparison of the T2Dx instrument with T2Candida assay and automated blood culture in the detection of Candida species using seeded blood samples.
PubMed Identifier: 24135411
author list: Beyda ND, Alam MJ, Garey KW
published in: Diagnostic microbiology and infectious disease
information resource reference: Comparison of the T2Dx instrument with T2Candida assay and automated blood culture in the detection of Candida species using seeded blood samples. Diagn Microbiol Infect Dis. 2013 Dec; 77(4):324-6.
journal title abbreviation: Diagn Microbiol Infect Dis
publication date: 2013-10-14T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Treatment of Candida famata bloodstream infections: case series and review of the literature.
PubMed Identifier: 23085777
author list: Beyda ND, Chuang SH, Alam MJ, Shah DN, Ng TM, McCaskey L, Garey KW
published in: The Journal of antimicrobial chemotherapy
information resource reference: Treatment of Candida famata bloodstream infections: case series and review of the literature. J Antimicrob Chemother. 2013 Feb; 68(2):438-43.
journal title abbreviation: J Antimicrob Chemother
publication date: 2012-10-19T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Inhibition of biofilm formation by esomeprazole in Pseudomonas aeruginosa and Staphylococcus aureus.
PubMed Identifier: 22664967
author list: Singh V, Arora V, Alam MJ, Garey KW
published in: Antimicrobial agents and chemotherapy
information resource reference: Inhibition of biofilm formation by esomeprazole in Pseudomonas aeruginosa and Staphylococcus aureus. Antimicrob Agents Chemother. 2012 Aug; 56(8):4360-4.
journal title abbreviation: Antimicrob Agents Chemother
publication date: 2012-06-04T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Professor
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Lecturer
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position in organization: University of Houston

Lecturer
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position in department: Pharmacy Practice and Translational Research
position in division: College of Pharmacy
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HR job title: Lecturer
position in organization: University of Houston

Lecturer
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position in department: Pharmacy Practice and Translational Research
position in division: College of Pharmacy
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HR job title: Lecturer
position in organization: University of Houston

Associate Professor
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position in department: Pharmacy Practice and Translational Research
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HR job title: Associate Professor
position in organization: University of Houston

Professor
is primary position: true
position in department: Psychology
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HR job title: Professor
position in organization: University of Houston

Ribotyping
MeSH DescriptorUI: D021521
MeSH semantic group name: Phenomena
MeSH semantic group name: Procedures
number of authors: 3
number of publications: 26
uniqueness weight: 0.983739
type: Concept