Pharmacological and Pharmaceutical Sciences
Pharmacy Practice and Translational Research
Premaratne A, Basu S, Bagchi A, Zhou T, Feng Q, Lin CY
Liver X Receptor Ligand GAC0001E5 Downregulates Antioxidant Capacity and ERBB2/HER2 Expression in HER2-Positive Breast Cancer Cells. Cancers (Basel). 2024 Apr 25; 16(9).
Liver X Receptor Ligand GAC0001E5 Downregulates Antioxidant Capacity and ERBB2/HER2 Expression in HER2-Positive Breast Cancer Cells.
Premaratne A, Ho C, Basu S, Khan AF, Bawa-Khalfe T, Lin CY
Liver X Receptor Inverse Agonist GAC0001E5 Impedes Glutaminolysis and Disrupts Redox Homeostasis in Breast Cancer Cells. Biomolecules. 2023 02 10; 13(2).
Liver X Receptor Inverse Agonist GAC0001E5 Impedes Glutaminolysis and Disrupts Redox Homeostasis in Breast Cancer Cells.
Lee SA, Ho C, Troxler M, Lin CY, Chung SH
Non-Metabolic Functions of PKM2 Contribute to Cervical Cancer Cell Proliferation Induced by the HPV16 E7 Oncoprotein. Viruses. 2021 03 08; 13(3).
Non-Metabolic Functions of PKM2 Contribute to Cervical Cancer Cell Proliferation Induced by the HPV16 E7 Oncoprotein.
Srivastava S, Widmann S, Ho C, Nguyen D, Nguyen A, Premaratne A, Gustafsson J?, Lin CY
International journal of molecular sciences
Novel Liver X Receptor Ligand GAC0001E5 Disrupts Glutamine Metabolism and Induces Oxidative Stress in Pancreatic Cancer Cells. Int J Mol Sci. 2020 Dec 17; 21(24).
Novel Liver X Receptor Ligand GAC0001E5 Disrupts Glutamine Metabolism and Induces Oxidative Stress in Pancreatic Cancer Cells.
Alcoholism, clinical and experimental research
Genes Associated with Calcium Signaling are Involved in Alcohol-Induced Breast Cancer Growth. Alcohol Clin Exp Res. 2021 01; 45(1):79-91.
Genes Associated with Calcium Signaling are Involved in Alcohol-Induced Breast Cancer Growth.
Progesterone Receptor Is a Haploinsufficient Tumor-Suppressor Gene in Cervical Cancer. Mol Cancer Res. 2021 01; 19(1):42-47.
Progesterone Receptor Is a Haploinsufficient Tumor-Suppressor Gene in Cervical Cancer.
Chaurasiya S, Widmann S, Botero C, Lin CY, Gustafsson J?, Strom AM
Estrogen receptor ? exerts tumor suppressive effects in prostate cancer through repression of androgen receptor activity. PLoS One. 2020; 15(5):e0226057.
Estrogen receptor ? exerts tumor suppressive effects in prostate cancer through repression of androgen receptor activity.
Mesmar F, Dai B, Ibrahim A, Hases L, Jafferali MH, Jose Augustine J, DiLorenzo S, Kang Y, Zhao Y, Wang J, Kim M, Lin CY, Berkenstam A, Fleming J, Williams C
Clinical candidate and genistein analogue AXP107-11 has chemoenhancing functions in pancreatic adenocarcinoma through G protein-coupled estrogen receptor signaling. Cancer Med. 2019 12; 8(18):7705-7719.
Clinical candidate and genistein analogue AXP107-11 has chemoenhancing functions in pancreatic adenocarcinoma through G protein-coupled estrogen receptor signaling.
Stender JD, Nwachukwu JC, Kastrati I, Kim Y, Strid T, Yakir M, Srinivasan S, Nowak J, Izard T, Rangarajan ES, Carlson KE, Katzenellenbogen JA, Yao XQ, Grant BJ, Leong HS, Lin CY, Frasor J, Nettles KW, Glass CK
Structural and Molecular Mechanisms of Cytokine-Mediated Endocrine Resistance in Human Breast Cancer Cells. Mol Cell. 2017 Mar 16; 65(6):1122-1135.e5.
Structural and Molecular Mechanisms of Cytokine-Mediated Endocrine Resistance in Human Breast Cancer Cells.
Lin CY, Kleinbrink EL, Dachet F, Cai J, Ju D, Goldstone A, Wood EJ, Liu K, Jia H, Goustin AS, Kosir MA, Thepsuwan P, Lipovich L
Primate-specific oestrogen-responsive long non-coding RNAs regulate proliferation and viability of human breast cancer cells. Open Biol. 2016 12; 6(12).
Primate-specific oestrogen-responsive long non-coding RNAs regulate proliferation and viability of human breast cancer cells.
Soncini M, Corna G, Moresco M, Coltella N, Restuccia U, Maggioni D, Raccosta L, Lin CY, Invernizzi F, Crocchiolo R, Doglioni C, Traversari C, Bachi A, Bernardi R, Bordignon C, Gustafsson J?, Russo V
Proceedings of the National Academy of Sciences of the United States of America
24-Hydroxycholesterol participates in pancreatic neuroendocrine tumor development. Proc Natl Acad Sci U S A. 2016 10 11; 113(41):E6219-E6227.
24-Hydroxycholesterol participates in pancreatic neuroendocrine tumor development.
The emerging roles of liver X receptors and their ligands in cancer. Expert Opin Ther Targets. 2016; 20(1):61-71.
The emerging roles of liver X receptors and their ligands in cancer.
Candelaria NR, Weldon R, Muthusamy S, Nguyen-Vu T, Addanki S, Yoffou PH, Karaboga H, Blessing AM, Bollu LR, Miranda RC, Lin CY
Alcohol Regulates Genes that Are Associated with Response to Endocrine Therapy and Attenuates the Actions of Tamoxifen in Breast Cancer Cells. PLoS One. 2015; 10(12):e0145061.
Alcohol Regulates Genes that Are Associated with Response to Endocrine Therapy and Attenuates the Actions of Tamoxifen in Breast Cancer Cells.
Targeting liver X receptors in cancer therapeutics. Nat Rev Cancer. 2015 Apr; 15(4):216-24.
Targeting liver X receptors in cancer therapeutics.
Wall EH, Hewitt SC, Case LK, Lin CY, Korach KS, Teuscher C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
The role of genetics in estrogen responses: a critical piece of an intricate puzzle. FASEB J. 2014 Dec; 28(12):5042-54.
The role of genetics in estrogen responses: a critical piece of an intricate puzzle.
Candelaria NR, Addanki S, Zheng J, Nguyen-Vu T, Karaboga H, Dey P, Gabbi C, Vedin LL, Liu K, Wu W, Jonsson PK, Lin JZ, Su F, Bollu LR, Hodges SE, McElhany AL, Issazadeh MA, Fisher WE, Ittmann MM, Steffensen KR, Gustafsson J?, Lin CY
Antiproliferative effects and mechanisms of liver X receptor ligands in pancreatic ductal adenocarcinoma cells. PLoS One. 2014; 9(9):e106289.
Antiproliferative effects and mechanisms of liver X receptor ligands in pancreatic ductal adenocarcinoma cells.
Bondesson M, Hao R, Lin CY, Williams C, Gustafsson J?
Estrogen receptor signaling during vertebrate development. Biochim Biophys Acta. 2015 Feb; 1849(2):142-51.
Estrogen receptor signaling during vertebrate development.
Wall EH, Case LK, Hewitt SC, Nguyen-Vu T, Candelaria NR, Teuscher C, Lin CY
Genetic control of ductal morphology, estrogen-induced ductal growth, and gene expression in female mouse mammary gland. Endocrinology. 2014 Aug; 155(8):3025-35.
Genetic control of ductal morphology, estrogen-induced ductal growth, and gene expression in female mouse mammary gland.
Oestrogen receptors in breast cancer: basic mechanisms and clinical implications. Ecancermedicalscience. 2013 Nov 05; 7:370.
Oestrogen receptors in breast cancer: basic mechanisms and clinical implications.
Estrogen receptor alpha: molecular mechanisms and emerging insights. J Cell Biochem. 2013 Oct; 114(10):2203-8.
Estrogen receptor alpha: molecular mechanisms and emerging insights.
Aydogdu E, Katchy A, Tsouko E, Lin CY, Haldos?n LA, Helguero L, Williams C
MicroRNA-regulated gene networks during mammary cell differentiation are associated with breast cancer. Carcinogenesis. 2012 Aug; 33(8):1502-11.
MicroRNA-regulated gene networks during mammary cell differentiation are associated with breast cancer.