Ming Hu to Male
This is a "connection" page, showing publications Ming Hu has written about Male.
Connection Strength
1.831
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Fecal SN-38 Content as a Surrogate Predictor of Intestinal SN-38 Exposure and Associated Irinotecan-induced Severe Delayed-Onset Diarrhea by a Novel Use of the Spectrofluorimetric Method. Pharm Res. 2024 Sep; 41(9):1855-1867.
Score: 0.120
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Optimized rat models better mimic patients with irinotecan-induced severe diarrhea. Toxicol Mech Methods. 2024 Jun; 34(5):572-583.
Score: 0.116
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Hepatoenteric recycling is a new disposition mechanism for orally administered phenolic drugs and phytochemicals in rats. Elife. 2021 07 01; 10.
Score: 0.097
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Rapid intestinal glucuronidation and hepatic glucuronide recycling contributes significantly to the enterohepatic circulation of icaritin and its glucuronides in vivo. Arch Toxicol. 2020 Nov; 94(11):3737-3749.
Score: 0.092
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Pharmacokinetic and Metabolic Profiling of Key Active Components of Dietary Supplement Magnolia officinalis Extract for Prevention against Oral Carcinoma. J Agric Food Chem. 2020 Jun 17; 68(24):6576-6587.
Score: 0.090
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Development and validation of an LC-MS/MS method for the quantification of flavonoid glucuronides (wogonoside, baicalin, and apigenin-glucuronide) in the bile and blood samples: Application to a portal vein infusion study. Anal Biochem. 2020 07 15; 601:113723.
Score: 0.089
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Acute changes in colonic PGE2 levels as a biomarker of efficacy after treatment of the Pirc (F344/NTac-Apc?am1137) rat with celecoxib. Inflamm Res. 2020 Jan; 69(1):131-137.
Score: 0.087
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LC-MS/MS quantification of sulfotransferases is better than conventional immunogenic methods in determining human liver SULT activities: implication in precision medicine. Sci Rep. 2017 Jun 20; 7(1):3858.
Score: 0.073
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Transport-Glucuronidation Classification System and PBPK Modeling: New Approach To Predict the Impact of Transporters on Disposition of Glucuronides. Mol Pharm. 2017 09 05; 14(9):2884-2898.
Score: 0.072
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Disposition of flavonoids via recycling: Direct biliary excretion of enterically or extrahepatically derived flavonoid glucuronides. Mol Nutr Food Res. 2016 May; 60(5):1006-19.
Score: 0.067
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Development and validation of an UPLC-MS/MS method for the quantification of irinotecan, SN-38 and SN-38 glucuronide in plasma, urine, feces, liver and kidney: Application to a pharmacokinetic study of irinotecan in rats. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Mar 15; 1015-1016:34-41.
Score: 0.067
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Factors Influencing Oral Bioavailability of Thai Mango Seed Kernel Extract and Its Key Phenolic Principles. Molecules. 2015 Nov 30; 20(12):21254-73.
Score: 0.066
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Curcumin Affects Phase II Disposition of Resveratrol Through Inhibiting Efflux Transporters MRP2 and BCRP. Pharm Res. 2016 Mar; 33(3):590-602.
Score: 0.065
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Development and validation of an UPLC-MS/MS method for the quantification of columbin in biological matrices: Applications to absorption, metabolism, and pharmacokinetic studies. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 01; 1002:13-8.
Score: 0.064
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Quantitation of celecoxib and four of its metabolites in rat blood by UPLC-MS/MS clarifies their blood distribution patterns and provides more accurate pharmacokinetics profiles. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Sep 15; 1001:202-11.
Score: 0.064
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Development and validation of an UPLC-MS/MS method for the quantification of ethoxzolamide in blood, brain tissue, and bioequivalent buffers: applications to absorption, brain distribution, and pharmacokinetic studies. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Apr 01; 986-987:54-9.
Score: 0.062
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SIRT1 inhibition-induced senescence as a strategy to prevent prostate cancer progression. Mol Carcinog. 2022 Jul; 61(7):702-716.
Score: 0.026
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A positive-negative switching LC-MS/MS method for quantification of fenoldopam and its phase II metabolites: Applications to a pharmacokinetic study in rats. J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Aug 01; 1179:122854.
Score: 0.024
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UGT1A1 dysfunction increases liver burden and aggravates hepatocyte damage caused by long-term bilirubin metabolism disorder. Biochem Pharmacol. 2021 Aug; 190:114592.
Score: 0.024
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A randomized, double-blind, placebo-controlled, single and multiple ascending dose Phase 1 study to determine the safety, pharmacokinetics and food and faecal microbiome effects of ibezapolstat administered orally to healthy subjects. J Antimicrob Chemother. 2020 12 01; 75(12):3635-3643.
Score: 0.023
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Development and validation of ultra-high-performance liquid chromatography-mass spectrometry method for the determination of raloxifene and its phase II metabolites in plasma: Application to pharmacokinetic studies in rats. J Sep Sci. 2020 Dec; 43(24):4414-4423.
Score: 0.023
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Insight into tartrate inhibition patterns in vitro and in vivo based on cocrystal structure with UDP-glucuronosyltransferase 2B15. Biochem Pharmacol. 2020 Feb; 172:113753.
Score: 0.022
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Metabolic profiles of Xiao Chai Hu Tang in mouse plasma, bile and urine by the UHPLC-ESI-Q-TOF/MS technique. J Chromatogr B Analyt Technol Biomed Life Sci. 2019 Oct 01; 1128:121767.
Score: 0.021
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Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Determine the Disposition of Esculetin-7-O-Glucuronide and 4-Methylesculetin-7-O-Glucuronide. Drug Metab Dispos. 2019 03; 47(3):203-214.
Score: 0.020
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Xiao-Chai-Hu-Tang (XCHT) Intervening Irinotecan's Disposition: The Potential of XCHT in Alleviating Irinotecan-Induced Diarrhea. Curr Cancer Drug Targets. 2019; 19(7):551-560.
Score: 0.020
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Age-related changes in hepatic expression and activity of drug metabolizing enzymes in male wild-type and breast cancer resistance protein knockout mice. Biopharm Drug Dispos. 2018 Jul; 39(7):344-353.
Score: 0.020
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Impact of diet on irinotecan toxicity in mice. Chem Biol Interact. 2018 Aug 01; 291:87-94.
Score: 0.020
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Tissue Distribution and Gender-Specific Protein Expression of Cytochrome P450 in five Mouse Genotypes with a Background of FVB. Pharm Res. 2018 Apr 10; 35(6):114.
Score: 0.019
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Simultaneous determination of tilianin and its metabolites in mice using ultra-high-performance liquid chromatography with tandem mass spectrometry and its application to a pharmacokinetic study. Biomed Chromatogr. 2018 Apr; 32(4).
Score: 0.019
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An UPLC-MS/MS method for quantifying tetrandrine and its metabolite berbamine in human blood: Application to a human pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Dec 01; 1070:92-96.
Score: 0.019
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Profiles and Gender-Specifics of UDP-Glucuronosyltransferases and Sulfotransferases Expressions in the Major Metabolic Organs of Wild-Type and Efflux Transporter Knockout FVB Mice. Mol Pharm. 2017 Sep 05; 14(9):2967-2976.
Score: 0.018
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Development of a validated UPLC-MS/MS method for determination of humantenmine in rat plasma and its application in pharmacokinetics and bioavailability studies. Biomed Chromatogr. 2017 Dec; 31(12).
Score: 0.018
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Sulfotransferases and Breast Cancer Resistance Protein Determine the Disposition of Calycosin in Vitro and in Vivo. Mol Pharm. 2017 Sep 05; 14(9):2917-2929.
Score: 0.018
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Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Regulate the Disposition of Acacetin Glucuronides. Pharm Res. 2017 Jul; 34(7):1402-1415.
Score: 0.018
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High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences. Drug Metab Dispos. 2017 06; 45(6):624-634.
Score: 0.018
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Metabolic Disposition of Luteolin Is Mediated by the Interplay of UDP-Glucuronosyltransferases and Catechol-O-Methyltransferases in Rats. Drug Metab Dispos. 2017 03; 45(3):306-315.
Score: 0.018
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In Vivo Exposure of Kaempferol Is Driven by Phase II Metabolic Enzymes and Efflux Transporters. AAPS J. 2016 Sep; 18(5):1289-1299.
Score: 0.017
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Characterization of oxygenated metabolites of ginsenoside Rg1 in plasma and urine of rat. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Jul 15; 1026:75-86.
Score: 0.017
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SGLT-1 Transport and Deglycosylation inside Intestinal Cells Are Key Steps in the Absorption and Disposition of Calycosin-7-O-?-d-Glucoside in Rats. Drug Metab Dispos. 2016 Mar; 44(3):283-96.
Score: 0.016
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Species- and gender-dependent differences in the glucuronidation of a flavonoid glucoside and its aglycone determined using expressed UGT enzymes and microsomes. Biopharm Drug Dispos. 2015 Dec; 36(9):622-35.
Score: 0.016
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Severely Impaired and Dysregulated Cytochrome P450 Expression and Activities in Hepatocellular Carcinoma: Implications for Personalized Treatment in Patients. Mol Cancer Ther. 2015 Dec; 14(12):2874-86.
Score: 0.016
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Simultaneous determinations of 17 marker compounds in Xiao-Chai-Hu-Tang by LC-MS/MS: Application to its pharmacokinetic studies in mice. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 15; 1003:12-21.
Score: 0.016
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A combined strategy of mass fragmentation, post-column cobalt complexation and shift in ultraviolet absorption spectra to determine the uridine 5'-diphospho-glucuronosyltransferase metabolism profiling of flavones after oral administration of a flavone mixture in rats. J Chromatogr A. 2015 May 22; 1395:116-28.
Score: 0.016
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Characterization of oxygenated metabolites of ginsenoside Rb1 in plasma and urine of rat. J Agric Food Chem. 2015 Mar 18; 63(10):2689-700.
Score: 0.016