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Ming Hu

TitleProfessor
InstitutionUniversity of Houston
DepartmentPharmacological and Pharmaceutical Sciences
Address4800 Calhoun Rd
Houston TX 77004
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    Collapse Research 
    Collapse research activities and funding
    U01FD008303     (ZHANG, FENG)Sep 1, 2024 - Aug 31, 2027
    NIH
    Developing PBPK-model based mechanistic IVIVC for PLGA implants
    Role: Co-Principal Investigator
    R01DE033321     (HU, MING)Sep 21, 2023 - Sep 20, 2025
    NIH
    Elucidating High Oral Fluid Exposure Mechanisms of Buprenorphine to Reduce Dental Caries
    Role: Principal Investigator
    R41CA275454     (SINGH, RASHIM)Apr 1, 2023 - Mar 31, 2025
    NIH
    Genetic Biocontainment Switch to Improve the Safety of Drug Detoxifying Bacteria in Preventing Chemotherapy-induced Diarrhea
    Role: Co-Principal Investigator
    R41CA261292     (SINGH, RASHIM)Sep 23, 2021 - Aug 31, 2022
    NIH
    Development of Drug Detoxifying Bacteria for Chemotherapy Induced Gut Injury
    Role: Co-Principal Investigator
    R01CA246209     (HU, MING)Sep 11, 2020 - Jun 30, 2025
    NIH
    Mechanistic and Pharmacokinetic Studies of Classical Chinese Formula Xiao Chai Hu Tang Against Irinotecan-Induced Gut Toxicities
    Role: Principal Investigator
    R01CA205633     (HU, MING ;WONG, STUART J;YOU, MING)Dec 8, 2016 - Nov 30, 2023
    NIH
    Inhibition of Oral Tumorigenesis by Antitumor B
    Role: Principal Investigator
    R01GM070737     (HU, MING)Jun 5, 2006 - Apr 30, 2020
    NIH
    Disposition of Flavonoids via Glucuronidation, Critical Role of Efflux Transporte
    Role: Principal Investigator
    R01CA087779     (HU, MING)Jul 1, 2002 - Jun 30, 2008
    NIH
    Absorption and Metabolism of Isoflavones
    Role: Principal Investigator
    R21AT000182     (HU, MING)Apr 1, 2000 - Mar 31, 2003
    NIH
    DISPOSITION OF GINKGO FLAVONOIDS VIA RECYCLING
    Role: Principal Investigator
    R15HD033157     (HU, MING)Apr 1, 1996 - Mar 31, 1999
    NIH
    INTESTINAL PROLIDASE--POLYMORPHISM AND REGULATION
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Zheng Z, Chen J, Srinual S, Tumbas ?aponjac V, Yin T, Wang BY, Sun R, Hu M. Buprenorphine Salivary Gland Accumulation Sustaining High Oral Fluid Exposure and Increasing the Risk of Streptococcus mutans Biofilm Formation. J Addict Med. 2024 Dec 02. PMID: 39621545.
      Citations:    Fields:    
    2. Zheng Z, ?aponjac VT, Singh R, Chen J, Srinual S, Yin T, Sun R, Hu M. Correction: Fecal SN-38 Content as a Surrogate Predictor of Intestinal SN-38 Exposure and Associated Irinotecan-induced Severe Delayed-Onset Diarrhea by a Novel Use of the Spectrofluorimetric Method. Pharm Res. 2024 Oct; 41(10):2075. PMID: 39349694.
      Citations:    Fields:    
    3. Zheng Z, ?aponjac VT, Singh R, Chen J, Srinual S, Yin T, Sun R, Hu M. Fecal SN-38 Content as a Surrogate Predictor of Intestinal SN-38 Exposure and Associated Irinotecan-induced Severe Delayed-Onset Diarrhea by a Novel Use of the Spectrofluorimetric Method. Pharm Res. 2024 Sep; 41(9):1855-1867. PMID: 39138788.
      Citations:    Fields:    Translation:Animals
    4. Waldron-Young E, Wijitrmektong W, Choi R, Whitman GR, Hulverson MA, Charania R, Keelaghan A, Li L, Srinual S, Nikhar S, McNamara CW, Love MS, Huerta L, Bakowski MA, Hu M, Van Voorhis WC, Mead JR, Cuny GD. Pyridopyrimidinones as a new chemotype of calcium dependent protein kinase 1 (CDPK1) inhibitors for Cryptosporidium. Mol Biochem Parasitol. 2024 12; 260:111637. PMID: 38901801; PMCID: PMC11629397.
      Citations:    Fields:    Translation:HumansAnimalsCells
    5. Lethe MCL, Bui D, Hu M, Wang X, Singh R, Chan CTY. Discovering New Substrates of a UDP-Glycosyltransferase with a High-Throughput Method. Int J Mol Sci. 2024 Feb 27; 25(5). PMID: 38473971; PMCID: PMC10931590.
      Citations:    Fields:    Translation:Animals
    6. Zheng Z, Du T, Gao S, Yin T, Li L, Zhu L, Singh R, Sun R, Hu M. Optimized rat models better mimic patients with irinotecan-induced severe diarrhea. Toxicol Mech Methods. 2024 Jun; 34(5):572-583. PMID: 38390772; PMCID: PMC11095999.
      Citations: 1     Fields:    Translation:HumansAnimals
    7. Hu M. Where will Medicines that Serve the Global South and Economically Disadvantaged People Come From? Curr Drug Metab. 2024; 25(1):1. PMID: 38956834.
      Citations:    Fields:    Translation:Humans
    8. Li C, Wang Y, Gao S, Hu M, You M. The Chemoprevention Effects of Two Herbal Mixtures on Chemically Induced Lung Tumorigenesis in Mice. Pharmaceuticals (Basel). 2023 Nov 30; 16(12). PMID: 38139793; PMCID: PMC10748223.
      Citations:    
    9. Zhang Q, Chen X, Palen K, Johnson B, Bui D, Xiong D, Pan J, Hu M, Wang Y, You M. Cancer chemoprevention with PV-1, a novel Prunella vulgaris-containing herbal mixture that remodels the tumor immune microenvironment in mice. Front Immunol. 2023; 14:1196434. PMID: 38077406; PMCID: PMC10704350.
      Citations: 1     Fields:    Translation:Animals
    10. Xie Z, Wang L, Chen J, Zheng Z, Srinual S, Guo A, Sun R, Hu M. Reduction of systemic exposure and side effects by intra-articular injection of anti-inflammatory agents for osteoarthritis: what is the safer strategy? J Drug Target. 2023 07; 31(6):596-611. PMID: 37249274.
      Citations: 1     Fields:    Translation:Humans
    11. McKinney A, Hu M, Hoskins A, Mohammadyar A, Naeem N, Jing J, Patel SS, Sheth BR, Jiang X. Cellular composition and circuit organization of the locus coeruleus of adult mice. Elife. 2023 02 03; 12. PMID: 36734517; PMCID: PMC9934863.
      Citations: 10     Fields:    Translation:AnimalsCells
    12. Zheng Z, Srinual S, Chen J, Li L, Du T, Hu M, Sun R, Gao S. Herbal Medicines as Adjuvants for the Treatment of Chemotherapy-Induced Diarrhea. Curr Drug Metab. 2023; 24(6):422-433. PMID: 37592799.
      Citations:    Fields:    Translation:HumansAnimals
    13. Bui D, McWilliams LA, Wu L, Zhou H, Wong SJ, You M, Chow DS, Singh R, Hu M. Pharmacokinetic Basis for Using Saliva Matrine Concentrations as a Clinical Compliance Monitoring in Antitumor B Chemoprevention Trials in Humans. Cancers (Basel). 2022 Dec 23; 15(1). PMID: 36612086; PMCID: PMC9817974.
      Citations: 2     
    14. Tao G, Dagher F, Li L, Singh R, Hu M, Ghose R. Corrigendum to "Irinotecan decreases intestinal UDP-glucuronosyltransferase (UGT) 1A1 via TLR4/MyD88 pathway prior to the onset of diarrhea" [Food Chem. Toxicol. 166 (2022) 113246]. Food Chem Toxicol. 2023 Jan; 171:113547. PMID: 36495622.
      Citations:    Fields:    
    15. Li L, Sun R, Zenga J, Himburg H, Wang L, Duan S, Liu J, Bui D, Xie Z, Du T, Xie L, Yin T, Wong S, Gao S, Hu M. Comparison of Absolute Expression and Turnover Number of COX-1 and COX-2 in Human and Rodent Cells and Tissues. J Inflamm Res. 2022; 15:4435-4447. PMID: 35958187; PMCID: PMC9359786.
      Citations: 2     
    16. Gao S, Sun R, Singh R, Yu So S, Chan CTY, Savidge T, Hu M. The role of gut microbial ?-glucuronidase in drug disposition and development. Drug Discov Today. 2022 10; 27(10):103316. PMID: 35820618; PMCID: PMC9717552.
      Citations: 8     Fields:    Translation:Animals
    17. Tao G, Dagher F, Li L, Singh R, Hu M, Ghose R. Irinotecan decreases intestinal UDP-glucuronosyltransferase (UGT) 1A1 via TLR4/MyD88 pathway prior to the onset of diarrhea. Food Chem Toxicol. 2022 Aug; 166:113246. PMID: 35728726.
      Citations:    Fields:    Translation:Animals
    18. Yao J, Huang M, Shen Q, Ding M, Yu S, Guo Y, Lin Y, Zheng Y, Chen W, Yan W, Liu Z, Wang D, Hu M, Lu L. c-Myc-PD-L1 Axis Sustained Gemcitabine-Resistance in Pancreatic Cancer. Front Pharmacol. 2022; 13:851512. PMID: 35586061; PMCID: PMC9108354.
      Citations: 5     
    19. Huang SB, Rivas P, Yang X, Lai Z, Chen Y, Schadler KL, Hu M, Reddick RL, Ghosh R, Kumar AP. SIRT1 inhibition-induced senescence as a strategy to prevent prostate cancer progression. Mol Carcinog. 2022 Jul; 61(7):702-716. PMID: 35452563; PMCID: PMC10161240.
      Citations: 5     Fields:    Translation:HumansAnimals
    20. Wang X, Chen L, Li R, Xie Z, Hu M, Sun S, Li Z, Hao J, Lin B, Chen X, Xie L. Development of Rofecoxib-Based Fluorophores from ACQ to AIE by Positional Regioisomerization. Chempluschem. 2022 Apr; 87(4):e202100522. PMID: 35179314.
      Citations: 1     
    21. Wang L, Luo Q, Zeng S, Lou Y, Li X, Hu M, Lu L, Liu Z. Disordered farnesoid X receptor signaling is associated with liver carcinogenesis in Abcb11-deficient mice. J Pathol. 2021 Dec; 255(4):412-424. PMID: 34410012.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    22. Bui D, Yin T, Duan S, Wei B, Yang P, Wong SJ, You M, Singh R, Hu M. Pharmacokinetic Characterization and Bioavailability Barrier for the Key Active Components of Botanical Drug Antitumor B (ATB) in Mice for Chemoprevention of Oral Cancer. J Nat Prod. 2021 09 24; 84(9):2486-2495. PMID: 34463097; PMCID: PMC10607708.
      Citations: 2     Fields:    Translation:AnimalsCells
    23. Xie L, Li R, Zheng B, Xie Z, Fang X, Wang Y, Cuny GD, Li Z, Lin B, Chen X, Hu M. Development of Rofecoxib-Based Fluorescent Probes and Investigations on Their Solvatochromism, AIE Activity, Mechanochromism, and COX-2-Targeted Bioimaging. Anal Chem. 2021 09 07; 93(35):11991-12000. PMID: 34424685.
      Citations: 1     Fields:    Translation:Humans
    24. Du T, Sun R, Etim I, Zheng Z, Liang D, Hu M, Gao S. Age-and Region-Dependent Disposition of Raloxifene in Rats. Pharm Res. 2021 Aug; 38(8):1357-1367. PMID: 34322833; PMCID: PMC8452384.
      Citations:    Fields:    Translation:Animals
    25. Ebuzoeme C, Etim I, Ikimi A, Song J, Du T, Hu M, Liang D, Gao S. Glucuronides Hydrolysis by Intestinal Microbial ß-Glucuronidases (GUS) Is Affected by Sampling, Enzyme Preparation, Buffer pH, and Species. Pharmaceutics. 2021 Jul 08; 13(7). PMID: 34371734; PMCID: PMC8309147.
      Citations: 2     
    26. Du T, Sun R, Siddiqui N, Moatamed L, Zhang Y, Liang D, Hu M, Gao S. A positive-negative switching LC-MS/MS method for quantification of fenoldopam and its phase II metabolites: Applications to a pharmacokinetic study in rats. J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Aug 01; 1179:122854. PMID: 34242859; PMCID: PMC8403159.
      Citations: 1     Fields:    Translation:Animals
    27. Tu Y, Wang L, Rong Y, Tam V, Yin T, Gao S, Singh R, Hu M. Hepatoenteric recycling is a new disposition mechanism for orally administered phenolic drugs and phytochemicals in rats. Elife. 2021 07 01; 10. PMID: 34196607; PMCID: PMC8248983.
      Citations: 5     Fields:    Translation:Animals
    28. Su T, Huang S, Zhang Y, Guo Y, Zhang S, Guan J, Meng M, Liu L, Wang C, Yu D, Kwan HY, Huang Z, Huang Q, Lai-Han Leung E, Hu M, Wang Y, Liu Z, Lu L. miR-7/TGF-ß2 axis sustains acidic tumor microenvironment-induced lung cancer metastasis. Acta Pharm Sin B. 2022 Feb; 12(2):821-837. PMID: 35251919; PMCID: PMC8896986.
      Citations: 11     
    29. Zhang D, Wei C, Hop CECA, Wright MR, Hu M, Lai Y, Khojasteh SC, Humphreys WG. Intestinal Excretion, Intestinal Recirculation, and Renal Tubule Reabsorption Are Underappreciated Mechanisms That Drive the Distribution and Pharmacokinetic Behavior of Small Molecule Drugs. J Med Chem. 2021 Jun 10; 64(11):7045-7059. PMID: 34010555.
      Citations: 6     Fields:    Translation:HumansAnimals
    30. Liu D, Yu Q, Li Z, Zhang L, Hu M, Wang C, Liu Z. UGT1A1 dysfunction increases liver burden and aggravates hepatocyte damage caused by long-term bilirubin metabolism disorder. Biochem Pharmacol. 2021 Aug; 190:114592. PMID: 33961837.
      Citations: 6     Fields:    Translation:AnimalsCells
    31. Xie L, Li R, Zheng B, Xie Z, Fang X, Dai T, Wang X, Li L, Wang L, Cuny GD, Eriksen J, Tu D, Chen Z, Wang X, Chen X, Hu M. One-Step Transformation from Rofecoxib to a COX-2 NIR Probe for Human Cancer Tissue/Organoid Targeted Bioimaging. ACS Appl Bio Mater. 2021 03 15; 4(3):2723-2731. PMID: 35014311.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    32. Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-Gómez E, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almacellas E, Almasan A, Alonso A, Alonso GD, Altan-Bonnet N, Altieri DC, Álvarez ÉMC, Alves S, Alves da Costa C, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andrade-Silva M, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antas P, Antebi A, Antón Z, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Araújo WL, Araya J, Arden C, Arévalo MA, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Arnauné-Pelloquin L, Aroca A, Arroyo DS, Arsov I, Artero R, Asaro DML, Aschner M, Ashrafizadeh M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R, Avagliano L, Ávalos Y, Aveic S, Aveleira CA, Avin-Wittenberg T, Aydin Y, Ayton S, Ayyadevara S, Azzopardi M, Baba M, Backer JM, Backues SK, Bae DH, Bae ON, Bae SH, Baehrecke EH, Baek A, Baek SH, Baek SH, Bagetta G, Bagniewska-Zadworna A, Bai H, Bai J, Bai X, Bai Y, Bairagi N, Baksi S, Balbi T, Baldari CT, Balduini W, Ballabio A, Ballester M, Balazadeh S, Balzan R, Bandopadhyay R, Banerjee S, Banerjee S, Bánréti Á, Bao Y, Baptista MS, Baracca A, Barbati C, Bargiela A, Barilà D, Barlow PG, Barmada SJ, Barreiro E, Barreto GE, Bartek J, Bartel B, Bartolome A, Barve GR, Basagoudanavar SH, Bassham DC, Bast RC, Basu A, Batoko H, Batten I, Baulieu EE, Baumgarner BL, Bayry J, Beale R, Beau I, Beaumatin F, Bechara LRG, Beck GR, Beers MF, Begun J, Behrends C, Behrens GMN, Bei R, Bejarano E, Bel S, Behl C, Belaid A, Belgareh-Touzé N, Bellarosa C, Belleudi F, Belló Pérez M, Bello-Morales R, Beltran JSO, Beltran S, Benbrook DM, Bendorius M, Benitez BA, Benito-Cuesta I, Bensalem J, Berchtold MW, Berezowska S, Bergamaschi D, Bergami M, Bergmann A, Berliocchi L, Berlioz-Torrent C, Bernard A, Berthoux L, Besirli CG, Besteiro S, Betin VM, Beyaert R, Bezbradica JS, Bhaskar K, Bhatia-Kissova I, Bhattacharya R, Bhattacharya S, Bhattacharyya S, Bhuiyan MS, Bhutia SK, Bi L, Bi X, Biden TJ, Bijian K, Billes VA, Binart N, Bincoletto C, Birgisdottir AB, Bjorkoy G, Blanco G, Blas-Garcia A, Blasiak J, Blomgran R, Blomgren K, Blum JS, Boada-Romero E, Boban M, Boesze-Battaglia K, Boeuf P, Boland B, Bomont P, Bonaldo P, Bonam SR, Bonfili L, Bonifacino JS, Boone BA, Bootman MD, Bordi M, Borner C, Bornhauser BC, Borthakur G, Bosch J, Bose S, Botana LM, Botas J, Boulanger CM, Boulton ME, Bourdenx M, Bourgeois B, Bourke NM, Bousquet G, Boya P, Bozhkov PV, Bozi LHM, Bozkurt TO, Brackney DE, Brandts CH, Braun RJ, Braus GH, Bravo-Sagua R, Bravo-San Pedro JM, Brest P, Bringer MA, Briones-Herrera A, Broaddus VC, Brodersen P, Brodsky JL, Brody SL, Bronson PG, Bronstein JM, Brown CN, Brown RE, Brum PC, Brumell JH, Brunetti-Pierri N, Bruno D, Bryson-Richardson RJ, Bucci C, Buchrieser C, Bueno M, Buitrago-Molina LE, Buraschi S, Buch S, Buchan JR, Buckingham EM, Budak H, Budini M, Bultynck G, Burada F, Burgoyne JR, Burón MI, Bustos V, Büttner S, Butturini E, Byrd A, Cabas I, Cabrera-Benitez S, Cadwell K, Cai J, Cai L, Cai Q, Cairó M, Calbet JA, Caldwell GA, Caldwell KA, Call JA, Calvani R, Calvo AC, Calvo-Rubio Barrera M, Camara NO, Camonis JH, Camougrand N, Campanella M, Campbell EM, Campbell-Valois FX, Campello S, Campesi I, Campos JC, Camuzard O, Cancino J, Candido de Almeida D, Canesi L, Caniggia I, Canonico B, Cantí C, Cao B, Caraglia M, Caramés B, Carchman EH, Cardenal-Muñoz E, Cardenas C, Cardenas L, Cardoso SM, Carew JS, Carle GF, Carleton G, Carloni S, Carmona-Gutierrez D, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy. 2021 Jan; 17(1):1-382. PMID: 33634751; PMCID: PMC7996087.
      Citations: 1070     Fields:    Translation:HumansAnimalsCells
    33. Zhou Q, Xia B, Yin T, He Y, Ye L, Hu M. Overexpression of MRP3 in HeLa-UGT1A9 Cells Enhances Glucuronidation Capability of the Cells. Curr Drug Metab. 2021; 22(10):772-783. PMID: 34279197.
      Citations:    Fields:    Translation:HumansCells
    34. Garey KW, Begum K, Lancaster C, Gonzales-Luna A, Bui D, Mercier J, Seng Yue C, Ducharme MP, Hu M, Vince B, Silverman MH, Alam MJ, Kankam M. A randomized, double-blind, placebo-controlled, single and multiple ascending dose Phase 1 study to determine the safety, pharmacokinetics and food and faecal microbiome effects of ibezapolstat administered orally to healthy subjects. J Antimicrob Chemother. 2020 12 01; 75(12):3635-3643. PMID: 32892222; PMCID: PMC7662179.
      Citations: 6     Fields:    Translation:HumansCellsCTClinical Trials
    35. Du T, Sun R, Li L, Ebuzoeme C, Bui D, Zheng Z, Yin T, Liang D, Hu M, Gao S. Development and validation of ultra-high-performance liquid chromatography-mass spectrometry method for the determination of raloxifene and its phase II metabolites in plasma: Application to pharmacokinetic studies in rats. J Sep Sci. 2020 Dec; 43(24):4414-4423. PMID: 33119204; PMCID: PMC8452178.
      Citations: 3     Fields:    Translation:AnimalsCells
    36. Rong Y, Tu Y, Yin T, Meng Z, Dou G, Hu M. Rapid intestinal glucuronidation and hepatic glucuronide recycling contributes significantly to the enterohepatic circulation of icaritin and its glucuronides in vivo. Arch Toxicol. 2020 Nov; 94(11):3737-3749. PMID: 32918091.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    37. Tao G, Huang J, Moorthy B, Wang C, Hu M, Gao S, Ghose R. Potential role of drug metabolizing enzymes in chemotherapy-induced gastrointestinal toxicity and hepatotoxicity. Expert Opin Drug Metab Toxicol. 2020 Nov; 16(11):1109-1124. PMID: 32841068; PMCID: PMC8059872.
      Citations: 19     Fields:    Translation:HumansCells
    38. Bui D, Li L, Yin T, Wang X, Gao S, You M, Singh R, Hu M. Pharmacokinetic and Metabolic Profiling of Key Active Components of Dietary Supplement Magnolia officinalis Extract for Prevention against Oral Carcinoma. J Agric Food Chem. 2020 Jun 17; 68(24):6576-6587. PMID: 32348135; PMCID: PMC7604171.
      Citations: 6     Fields:    Translation:HumansAnimals
    39. Duan S, Niu L, Yin T, Li L, Gao S, Yuan D, Hu M. A novel strategy for screening bioavailable quality markers of traditional Chinese medicine by integrating intestinal absorption and network pharmacology: Application to Wu Ji Bai Feng Pill. Phytomedicine. 2020 May 16; 76:153226. PMID: 32521487.
      Citations: 7     Fields:    
    40. Suebsuwong C, Dai B, Pinkas DM, Duddupudi AL, Li L, Bufton JC, Schlicher L, Gyrd-Hansen M, Hu M, Bullock AN, Degterev A, Cuny GD. Receptor-interacting protein kinase 2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling inhibitors based on a 3,5-diphenyl-2-aminopyridine scaffold. Eur J Med Chem. 2020 Aug 15; 200:112417. PMID: 32505849; PMCID: PMC7338260.
      Citations: 7     Fields:    Translation:HumansCells
    41. Sun R, Zhu L, Li L, Song W, Gong X, Qi X, Wang Y, Ghose R, Gao S, Hu M, Liu Z. Irinotecan-mediated diarrhea is mainly correlated with intestinal exposure to SN-38: Critical role of gut Ugt. Toxicol Appl Pharmacol. 2020 07 01; 398:115032. PMID: 32387182; PMCID: PMC9235850.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    42. Tu Y, Zhou L, Li L, Wang L, Gao S, Hu M. Development and validation of an LC-MS/MS method for the quantification of flavonoid glucuronides (wogonoside, baicalin, and apigenin-glucuronide) in the bile and blood samples: Application to a portal vein infusion study. Anal Biochem. 2020 07 15; 601:113723. PMID: 32298642; PMCID: PMC9326899.
      Citations: 3     Fields:    Translation:Animals
    43. Zhang Q, Cheng G, Pan J, Zielonka J, Xiong D, Myers CR, Feng L, Shin SS, Kim YH, Bui D, Hu M, Bennett B, Schmainda K, Wang Y, Kalyanaraman B, You M. Magnolia extract is effective for the chemoprevention of oral cancer through its ability to inhibit mitochondrial respiration at complex I. Cell Commun Signal. 2020 Apr 07; 18(1):58. PMID: 32264893; PMCID: PMC7140380.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    44. Singh R, Lu R, Hu M. Flavonoids interference in common protein assays: Effect of position and degree of hydroxyl substitution. Anal Biochem. 2020 05 15; 597:113644. PMID: 32105737; PMCID: PMC9154353.
      Citations: 1     Fields:    Translation:Animals
    45. Zhang L, Zhu L, Qu W, Wu F, Hu M, Xie W, Liu Z, Wang C. Insight into tartrate inhibition patterns in vitro and in vivo based on cocrystal structure with UDP-glucuronosyltransferase 2B15. Biochem Pharmacol. 2020 Feb; 172:113753. PMID: 31837310.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    46. Yun C, Dashwood WM, Li L, Yin T, Ulusan AM, Shatzer K, Gao S, Ruan KH, Hu M. Acute changes in colonic PGE2 levels as a biomarker of efficacy after treatment of the Pirc (F344/NTac-Apc?am1137) rat with celecoxib. Inflamm Res. 2020 Jan; 69(1):131-137. PMID: 31797003.
      Citations: 5     Fields:    Translation:Animals
    47. Liu D, Zhang L, Duan LX, Wu JJ, Hu M, Liu ZQ, Wang CY. Potential of herb-drug / herb interactions between substrates and inhibitors of UGTs derived from herbal medicines. Pharmacol Res. 2019 Dec; 150:104510. PMID: 31678209.
      Citations: 8     Fields:    Translation:HumansAnimals
    48. Du T, Sun R, Du S, Gao S, Hu M, Zhang Y, Chen J, Yang G. Metabolic profiles of Xiao Chai Hu Tang in mouse plasma, bile and urine by the UHPLC-ESI-Q-TOF/MS technique. J Chromatogr B Analyt Technol Biomed Life Sci. 2019 Oct 01; 1128:121767. PMID: 31627161.
      Citations: 2     Fields:    Translation:Animals
    49. Li Y, Song W, Ou X, Luo G, Xie Y, Sun R, Wang Y, Qi X, Hu M, Liu Z, Zhu L. Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Determine the Disposition of Esculetin-7-O-Glucuronide and 4-Methylesculetin-7-O-Glucuronide. Drug Metab Dispos. 2019 03; 47(3):203-214. PMID: 30602435.
      Citations: 6     Fields:    
    50. Sun R, Basu S, Zeng M, Sunsong R, Li L, Ghose R, Wang W, Liu Z, Hu M, Gao S. Xiao-Chai-Hu-Tang (XCHT) Intervening Irinotecan's Disposition: The Potential of XCHT in Alleviating Irinotecan-Induced Diarrhea. Curr Cancer Drug Targets. 2019; 19(7):551-560. PMID: 31509102.
      Citations: 3     Fields:    Translation:Animals
    51. Wang L, Sun R, Zhang Q, Luo Q, Zeng S, Li X, Gong X, Li Y, Lu L, Hu M, Liu Z. An update on polyphenol disposition via coupled metabolic pathways. Expert Opin Drug Metab Toxicol. 2019 Feb; 15(2):151-165. PMID: 30583703.
      Citations: 10     Fields:    Translation:HumansAnimals
    52. Li Y, Lu L, Wang L, Qu W, Liu W, Xie Y, Zheng H, Wang Y, Qi X, Hu M, Zhu L, Liu Z. Interplay of Efflux Transporters with Glucuronidation and Its Impact on Subcellular Aglycone and Glucuronide Disposition: A Case Study with Kaempferol. Mol Pharm. 2018 Dec 03; 15(12):5602-5614. PMID: 30376625.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    53. Wang W, Qin JJ, Voruganti S, Nijampatnam B, Velu SE, Ruan KH, Hu M, Zhou J, Zhang R. Discovery and Characterization of Dual Inhibitors of MDM2 and NFAT1 for Pancreatic Cancer Therapy. Cancer Res. 2018 10 01; 78(19):5656-5667. PMID: 30217928; PMCID: PMC6435280.
      Citations: 27     Fields:    Translation:AnimalsCells
    54. Chua CYX, Jain P, Ballerini A, Bruno G, Hood RL, Gupte M, Gao S, Di Trani N, Susnjar A, Shelton K, Bushman LR, Folci M, Filgueira CS, Marzinke MA, Anderson PL, Hu M, Nehete P, Arduino RC, Sastry JK, Grattoni A. Transcutaneously refillable nanofluidic implant achieves sustained level of tenofovir diphosphate for HIV pre-exposure prophylaxis. J Control Release. 2018 Sep 28; 286:315-325. PMID: 30092254; PMCID: PMC6345255.
      Citations: 38     Fields:    Translation:HumansAnimalsPHPublic Health
    55. Zheng H, Wang L, Zeng S, Chen J, Wang H, Yu J, Gong X, Jiang H, Yang X, Qi X, Wang Y, Lu L, Hu M, Zhu L, Liu Z. Age-related changes in hepatic expression and activity of drug metabolizing enzymes in male wild-type and breast cancer resistance protein knockout mice. Biopharm Drug Dispos. 2018 Jul; 39(7):344-353. PMID: 30016542.
      Citations: 3     Fields:    Translation:AnimalsCells
    56. Mallick P, Shah P, Ittmann MM, Trivedi M, Hu M, Gao S, Ghose R. Impact of diet on irinotecan toxicity in mice. Chem Biol Interact. 2018 Aug 01; 291:87-94. PMID: 29913120.
      Citations: 5     Fields:    Translation:Animals
    57. Ma Y, He Y, Yin T, Chen H, Gao S, Hu M. Metabolism of Phenolic Compounds in LPS-stimulated Raw264.7 Cells Can Impact Their Anti-inflammatory efficacy: Indication of Hesperetin. J Agric Food Chem. 2018 Jun 20; 66(24):6042-6052. PMID: 29792322.
      Citations: 6     Fields:    Translation:AnimalsCells
    58. Chen JM, Zhang QS, Li XY, Gong X, Ruan YJ, Zeng SJ, Lu LL, Qi XX, Wang Y, Hu M, Zhu LJ, Liu ZQ. Tissue Distribution and Gender-Specific Protein Expression of Cytochrome P450 in five Mouse Genotypes with a Background of FVB. Pharm Res. 2018 Apr 10; 35(6):114. PMID: 29637468.
      Citations: 5     Fields:    Translation:Animals
    59. Wang L, Chen Q, Zhu L, Zeng X, Li Q, Hu M, Wang X, Liu Z. Simultaneous determination of tilianin and its metabolites in mice using ultra-high-performance liquid chromatography with tandem mass spectrometry and its application to a pharmacokinetic study. Biomed Chromatogr. 2018 Apr; 32(4). PMID: 29144552.
      Citations:    Fields:    Translation:Animals
    60. Yang G, Zhang C, Hu P, Zhu M, Hu M, Gao S. An UPLC-MS/MS method for quantifying tetrandrine and its metabolite berbamine in human blood: Application to a human pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Dec 01; 1070:92-96. PMID: 29100757.
      Citations: 7     Fields:    Translation:Humans
    61. He Y, Zhou L, Gao S, Yin T, Tu Y, Rayford R, Wang X, Hu M. Development and validation of a sensitive LC-MS/MS method for simultaneous determination of eight tyrosine kinase inhibitors and its application in mice pharmacokinetic studies. J Pharm Biomed Anal. 2018 Jan 30; 148:65-72. PMID: 28965046; PMCID: PMC8519014.
      Citations: 8     Fields:    Translation:Animals
    62. Hu M, Wu B, Liu Z. Bioavailability of Polyphenols and Flavonoids in the Era of Precision Medicine. Mol Pharm. 2017 09 05; 14(9):2861-2863. PMID: 28870081.
      Citations: 27     Fields:    Translation:Humans
    63. Yang G, Lu W, Pan M, Zhang C, Zhou Y, Hu P, Hu M, Song G. An LC-MS/MS method for simultaneous determination of nine steroidal saponins from Paris polyphylla var. in rat plasma and its application to pharmacokinetic study. J Pharm Biomed Anal. 2017 Oct 25; 145:675-681. PMID: 28802242.
      Citations: 3     Fields:    Translation:Animals
    64. Yun C, Dashwood WM, Kwong LN, Gao S, Yin T, Ling Q, Singh R, Dashwood RH, Hu M. Accurate quantification of PGE2 in the polyposis in rat colon (Pirc) model by surrogate analyte-based UPLC-MS/MS. J Pharm Biomed Anal. 2018 Jan 30; 148:42-50. PMID: 28957718; PMCID: PMC5698167.
      Citations: 5     Fields:    Translation:Animals
    65. Chen J, Zheng H, Zeng S, Xie C, Li X, Yan T, Gong X, Lu L, Qi X, Wang Y, Hu M, Zhu L, Liu Z. Profiles and Gender-Specifics of UDP-Glucuronosyltransferases and Sulfotransferases Expressions in the Major Metabolic Organs of Wild-Type and Efflux Transporter Knockout FVB Mice. Mol Pharm. 2017 Sep 05; 14(9):2967-2976. PMID: 28661152.
      Citations: 4     Fields:    Translation:Animals
    66. Hu Y, Chen M, Wang Z, Lan Y, Tang L, Liu M, Zhao J, Hu M, Zhang L, Ye L. Development of a validated UPLC-MS/MS method for determination of humantenmine in rat plasma and its application in pharmacokinetics and bioavailability studies. Biomed Chromatogr. 2017 Dec; 31(12). PMID: 28557019.
      Citations: 4     Fields:    Translation:Animals
    67. Ma G, Zhang Y, Chen W, Tang Z, Xin X, Yang P, Liu X, Cai W, Hu M. Inhibition of Human UGT1A1-Mediated Bilirubin Glucuronidation by Polyphenolic Acids Impact Safety of Popular Salvianolic Acid A/B-Containing Drugs and Herbal Products. Mol Pharm. 2017 Sep 05; 14(9):2952-2966. PMID: 28603997.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    68. Xie C, Yan TM, Chen JM, Li XY, Zou J, Zhu LJ, Lu LL, Wang Y, Zhou FY, Liu ZQ, Hu M. LC-MS/MS quantification of sulfotransferases is better than conventional immunogenic methods in determining human liver SULT activities: implication in precision medicine. Sci Rep. 2017 Jun 20; 7(1):3858. PMID: 28634336; PMCID: PMC5478605.
      Citations: 10     Fields:    Translation:HumansCells
    69. Yang G, Ge S, Singh R, Basu S, Shatzer K, Zen M, Liu J, Tu Y, Zhang C, Wei J, Shi J, Zhu L, Liu Z, Wang Y, Gao S, Hu M. Glucuronidation: driving factors and their impact on glucuronide disposition. Drug Metab Rev. 2017 05; 49(2):105-138. PMID: 28266877; PMCID: PMC7660525.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    70. Yu J, Zhu L, Zheng H, Gong X, Jiang H, Chen J, Li Y, Zheng H, Qi X, Wang Y, Hu M, Lu L, Liu Z. Sulfotransferases and Breast Cancer Resistance Protein Determine the Disposition of Calycosin in Vitro and in Vivo. Mol Pharm. 2017 Sep 05; 14(9):2917-2929. PMID: 28445053.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    71. Jiang H, Yu J, Zheng H, Chen J, Wu J, Qi X, Wang Y, Wang X, Hu M, Zhu L, Liu Z. Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Regulate the Disposition of Acacetin Glucuronides. Pharm Res. 2017 Jul; 34(7):1402-1415. PMID: 28421306.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    72. Chen J, Zhu L, Li X, Zheng H, Yan T, Xie C, Zeng S, Yu J, Jiang H, Lu L, Qi X, Wang Y, Hu M, Liu Z. High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences. Drug Metab Dispos. 2017 06; 45(6):624-634. PMID: 28356314.
      Citations: 4     Fields:    
    73. Ge S, Wei Y, Yin T, Xu B, Gao S, Hu M. Transport-Glucuronidation Classification System and PBPK Modeling: New Approach To Predict the Impact of Transporters on Disposition of Glucuronides. Mol Pharm. 2017 09 05; 14(9):2884-2898. PMID: 28221813.
      Citations:    Fields:    Translation:HumansAnimalsCells
    74. Wang L, Chen Q, Zhu L, Li Q, Zeng X, Lu L, Hu M, Wang X, Liu Z. Metabolic Disposition of Luteolin Is Mediated by the Interplay of UDP-Glucuronosyltransferases and Catechol-O-Methyltransferases in Rats. Drug Metab Dispos. 2017 03; 45(3):306-315. PMID: 28031430; PMCID: PMC6041822.
      Citations: 12     Fields:    
    75. Ge S, Tu Y, Hu M. Challenges and Opportunities with Predicting in Vivo Phase II Metabolism via Glucuronidation from in Vitro Data. Curr Pharmacol Rep. 2016 Dec; 2(6):326-338. PMID: 28966903; PMCID: PMC5613675.
      Citations: 9     
    76. Zheng L, Zhu L, Zhao M, Shi J, Li Y, Yu J, Jiang H, Wu J, Tong Y, Liu Y, Hu M, Lu L, Liu Z. In Vivo Exposure of Kaempferol Is Driven by Phase II Metabolic Enzymes and Efflux Transporters. AAPS J. 2016 Sep; 18(5):1289-1299. PMID: 27393480; PMCID: PMC7702721.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    77. Wang M, Yang G, He Y, Xu B, Zeng M, Ge S, Yin T, Gao S, Hu M. Establishment and use of new MDCK II cells overexpressing both UGT1A1 and MRP2 to characterize flavonoid metabolism via the glucuronidation pathway. Mol Nutr Food Res. 2016 Sep; 60(9):1967-83. PMID: 26833852; PMCID: PMC5358013.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    78. Liu Y, Tong Y, Yang X, Li F, Zheng L, Liu W, Wu J, Ou R, Zhang G, Hu M, Liu Z, Lu L. Novel histone deacetylase inhibitors derived from Magnolia officinalis significantly enhance TRAIL-induced apoptosis in non-small cell lung cancer. Pharmacol Res. 2016 Sep; 111:113-125. PMID: 27268146.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    79. Tong Y, Liu Y, Zheng H, Zheng L, Liu W, Wu J, Ou R, Zhang G, Li F, Hu M, Liu Z, Lu L. Artemisinin and its derivatives can significantly inhibit lung tumorigenesis and tumor metastasis through Wnt/ß-catenin signaling. Oncotarget. 2016 May 24; 7(21):31413-28. PMID: 27119499; PMCID: PMC5058767.
      Citations: 52     Fields:    Translation:HumansAnimalsCells
    80. Yun C, Yin T, Shatzer K, Burrin DG, Cui L, Tu Y, Hu M. Determination of 7a-OH cholesterol by LC-MS/MS: Application in assessing the activity of CYP7A1 in cholestatic minipigs. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Jul 01; 1025:76-82. PMID: 27218859; PMCID: PMC5358015.
      Citations: 2     Fields:    Translation:AnimalsCells
    81. Jiamboonsri P, Pithayanukul P, Bavovada R, Leanpolchareanchai J, Gao S, Hu M. In?vitro glucuronidation of methyl gallate and pentagalloyl glucopyranose by liver microsomes. Drug Metab Pharmacokinet. 2016 Aug; 31(4):292-303. PMID: 27325020; PMCID: PMC7671852.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    82. Zeng M, Sun R, Basu S, Ma Y, Ge S, Yin T, Gao S, Zhang J, Hu M. Disposition of flavonoids via recycling: Direct biliary excretion of enterically or extrahepatically derived flavonoid glucuronides. Mol Nutr Food Res. 2016 May; 60(5):1006-19. PMID: 26843117; PMCID: PMC5358014.
      Citations: 18     Fields:    Translation:AnimalsCells
    83. Basu S, Zeng M, Yin T, Gao S, Hu M. Development and validation of an UPLC-MS/MS method for the quantification of irinotecan, SN-38 and SN-38 glucuronide in plasma, urine, feces, liver and kidney: Application to a pharmacokinetic study of irinotecan in rats. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Mar 15; 1015-1016:34-41. PMID: 26894853; PMCID: PMC5215916.
      Citations: 8     Fields:    Translation:Animals
    84. Wang JR, Tong TT, Yau LF, Chen CY, Bai LP, Ma J, Hu M, Liu L, Jiang ZH. Characterization of oxygenated metabolites of ginsenoside Rg1 in plasma and urine of rat. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Jul 15; 1026:75-86. PMID: 26809375.
      Citations: 4     Fields:    Translation:Animals
    85. Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Alg?l H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, B?nhegyi G, Bao H, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolom? A, Bassham DC, Bassi MT, Bast RC, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR, Becker C, Beckham JD, B?dard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, B?nard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, B?ckler S, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Boman A, Bonaldo P, Bordi M, Bosch J, Botana LM, Botti J, Bou G, Bouch? M, Bouchecareilh M, Boucher MJ, Boulton ME, Bouret SG, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady N, Braga VM, Brancolini C, Braus GH, Bravo-San Pedro JM, Brennan LA, Bresnick EH, Brest P, Bridges D, Bringer MA, Brini M, Brito GC, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Bruhat A, Brum PC, Brumell JH, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bultman SJ, Bultynck G, Bumbasirevic V, Burelle Y, Burke RE, Burmeister M, B?tikofer P, Caberlotto L, Cadwell K, Cahova M, Cai D, Cai J, Cai Q, Calatayud S, Camougrand N, Campanella M, Campbell GR, Campbell M, Campello S, Candau R, Caniggia I, Cantoni L, Cao L, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carlsson SR, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carra S, Carrier A, Carroll B, Casas C, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cederbaum AI, Ce?a V, Cenci S, Cerella C, Cervia D, Cetrullo S, Chaachouay H, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chamilos G, Chan EY, Chan MT, Chandra D, Chandra P, Chang CP, Chang RC, Chang TY, Chatham JC, Chatterjee S, Chauhan S, Che Y, Cheetham ME, Cheluvappa R, Chen CJ, Chen G, Chen GC, Chen G, Chen H, Chen JW, Chen JK, Chen M, Chen M, Chen P, Chen Q, Chen Q, Chen SD, Chen S, Chen SS, Chen W, Chen WJ, Chen WQ, Chen W, Chen X, Chen YH, Chen YG, Chen Y, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen Y, Chen Z, Chen Z, Cheng A, Cheng CH, Cheng H, Cheong H, Cherry S, Chesney J, Cheung CH, Chevet E, Chi HC, Chi SG, Chiacchiera F, Chiang HL, Chiarelli R, Chiariello M, Chieppa M, Chin LS, Chiong M, Chiu GN, Cho DH, Cho SG, Cho WC, Cho YY, Cho YS, Choi AM, Choi EJ, Choi EK, Choi J, Choi ME, Choi SI, Chou TF, Chouaib S, Choubey D, Choubey V, Chow KC, Chowdhury K, Chu CT, Chuang TH, Chun T, Chung H, Chung T, Chung YL, Chwae YJ, Cianfanelli V, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016; 12(1):1-222. PMID: 26799652; PMCID: PMC4835977.
      Citations: 2833     Fields:    Translation:HumansAnimals
    86. Shi J, Zheng H, Yu J, Zhu L, Yan T, Wu P, Lu L, Wang Y, Hu M, Liu Z. SGLT-1 Transport and Deglycosylation inside Intestinal Cells Are Key Steps in the Absorption and Disposition of Calycosin-7-O-?-d-Glucoside in Rats. Drug Metab Dispos. 2016 Mar; 44(3):283-96. PMID: 26658676.
      Citations: 5     Fields:    
    87. Dai P, Luo F, Wang Y, Jiang H, Wang L, Zhang G, Zhu L, Hu M, Wang X, Lu L, Liu Z. Species- and gender-dependent differences in the glucuronidation of a flavonoid glucoside and its aglycone determined using expressed UGT enzymes and microsomes. Biopharm Drug Dispos. 2015 Dec; 36(9):622-35. PMID: 26317684.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    88. Jiamboonsri P, Pithayanukul P, Bavovada R, Leanpolchareanchai J, Yin T, Gao S, Hu M. Factors Influencing Oral Bioavailability of Thai Mango Seed Kernel Extract and Its Key Phenolic Principles. Molecules. 2015 Nov 30; 20(12):21254-73. PMID: 26633325; PMCID: PMC6332320.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    89. Liu W, Shi J, Zhu L, Dong L, Luo F, Zhao M, Wang Y, Hu M, Lu L, Liu Z. Reductive metabolism of oxymatrine is catalyzed by microsomal CYP3A4. Drug Des Devel Ther. 2015; 9:5771-83. PMID: 26586934; PMCID: PMC4636097.
      Citations: 7     Fields:    Translation:HumansCells
    90. Yan T, Lu L, Xie C, Chen J, Peng X, Zhu L, Wang Y, Li Q, Shi J, Zhou F, Hu M, Liu Z. Severely Impaired and Dysregulated Cytochrome P450 Expression and Activities in Hepatocellular Carcinoma: Implications for Personalized Treatment in Patients. Mol Cancer Ther. 2015 Dec; 14(12):2874-86. PMID: 26516155; PMCID: PMC4674380.
      Citations: 29     Fields:    Translation:HumansCells
    91. Ge S, Yin T, Xu B, Gao S, Hu M. Curcumin Affects Phase II Disposition of Resveratrol Through Inhibiting Efflux Transporters MRP2 and BCRP. Pharm Res. 2016 Mar; 33(3):590-602. PMID: 26502886; PMCID: PMC4744546.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    92. Sun R, Zeng M, Du T, Li L, Yang G, Hu M, Gao S. Simultaneous determinations of 17 marker compounds in Xiao-Chai-Hu-Tang by LC-MS/MS: Application to its pharmacokinetic studies in mice. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 15; 1003:12-21. PMID: 26397748; PMCID: PMC4608253.
      Citations: 8     Fields:    Translation:Animals
    93. Yang G, Gao S, Sun R, Yin T, Hu M. Development and validation of an UPLC-MS/MS method for the quantification of columbin in biological matrices: Applications to absorption, metabolism, and pharmacokinetic studies. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 01; 1002:13-8. PMID: 26295697; PMCID: PMC4659646.
      Citations:    Fields:    Translation:Animals
    94. Ma Y, Gao S, Hu M. Quantitation of celecoxib and four of its metabolites in rat blood by UPLC-MS/MS clarifies their blood distribution patterns and provides more accurate pharmacokinetics profiles. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Sep 15; 1001:202-11. PMID: 26281772; PMCID: PMC4659650.
      Citations: 6     Fields:    Translation:Animals
    95. Yin T, Yang G, Ma Y, Xu B, Hu M, You M, Gao S. Developing an activity and absorption-based quality control platform for Chinese traditional medicine: Application to Zeng-Sheng-Ping(Antitumor B). J Ethnopharmacol. 2015 Aug 22; 172:195-201. PMID: 26099633; PMCID: PMC4541799.
      Citations: 8     Fields:    Translation:HumansCells
    96. Zhu L, Lu L, Zeng S, Luo F, Dai P, Wu P, Wang Y, Liu L, Hu M, Liu Z. UDP-Glucuronosyltransferases 1A6 and 1A9 are the Major Isozymes Responsible for the 7-O-Glucuronidation of Esculetin and 4-Methylesculetin in Human Liver Microsomes. Drug Metab Dispos. 2015 Jul; 43(7):977-83. PMID: 25854527; PMCID: PMC6067388.
      Citations: 2     Fields:    
    97. Li Q, Wang L, Dai P, Zeng X, Qi X, Zhu L, Yan T, Wang Y, Lu L, Hu M, Wang X, Liu Z. A combined strategy of mass fragmentation, post-column cobalt complexation and shift in ultraviolet absorption spectra to determine the uridine 5'-diphospho-glucuronosyltransferase metabolism profiling of flavones after oral administration of a flavone mixture in rats. J Chromatogr A. 2015 May 22; 1395:116-28. PMID: 25892633.
      Citations: 7     Fields:    Translation:AnimalsCells
    98. Ge S, Gao S, Yin T, Hu M. Determination of pharmacokinetics of chrysin and its conjugates in wild-type FVB and Bcrp1 knockout mice using a validated LC-MS/MS method. J Agric Food Chem. 2015 Mar 25; 63(11):2902-10. PMID: 25715997.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    99. Wang JR, Yau LF, Tong TT, Feng QT, Bai LP, Ma J, Hu M, Liu L, Jiang ZH. Characterization of oxygenated metabolites of ginsenoside Rb1 in plasma and urine of rat. J Agric Food Chem. 2015 Mar 18; 63(10):2689-700. PMID: 25737370.
      Citations: 4     Fields:    Translation:AnimalsCells
    100. Gao S, Zhao J, Yin T, Ma Y, Xu B, Moore AN, Dash PK, Hu M. Development and validation of an UPLC-MS/MS method for the quantification of ethoxzolamide in blood, brain tissue, and bioequivalent buffers: applications to absorption, brain distribution, and pharmacokinetic studies. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Apr 01; 986-987:54-9. PMID: 25706567; PMCID: PMC4507571.
      Citations:    Fields:    Translation:HumansAnimalsCells
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