"Glucuronides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Glycosides of GLUCURONIC ACID formed by the reaction of URIDINE DIPHOSPHATE GLUCURONIC ACID with certain endogenous and exogenous substances. Their formation is important for the detoxification of drugs, steroid excretion and BILIRUBIN metabolism to a more water-soluble compound that can be eliminated in the URINE and BILE.
| Descriptor ID |
D020719
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| MeSH Number(s) |
D02.241.081.844.915.162.500 D02.241.152.811.162.750 D02.241.511.902.915.162.750 D09.811.922.162.750
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Glucuronides".
Below are MeSH descriptors whose meaning is more specific than "Glucuronides".
This graph shows the total number of publications written about "Glucuronides" by people in this website by year, and whether "Glucuronides" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2010 | 2 | 0 | 2 |
| 2011 | 1 | 0 | 1 |
| 2015 | 0 | 4 | 4 |
| 2016 | 5 | 0 | 5 |
| 2017 | 3 | 0 | 3 |
| 2018 | 1 | 1 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Glucuronides" by people in Profiles.
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A positive-negative switching LC-MS/MS method for quantification of fenoldopam and its phase II metabolites: Applications to a pharmacokinetic study in rats. J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Aug 01; 1179:122854.
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Rapid intestinal glucuronidation and hepatic glucuronide recycling contributes significantly to the enterohepatic circulation of icaritin and its glucuronides in vivo. Arch Toxicol. 2020 Nov; 94(11):3737-3749.
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Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Determine the Disposition of Esculetin-7-O-Glucuronide and 4-Methylesculetin-7-O-Glucuronide. Drug Metab Dispos. 2019 03; 47(3):203-214.
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An update on polyphenol disposition via coupled metabolic pathways. Expert Opin Drug Metab Toxicol. 2019 Feb; 15(2):151-165.
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Interplay of Efflux Transporters with Glucuronidation and Its Impact on Subcellular Aglycone and Glucuronide Disposition: A Case Study with Kaempferol. Mol Pharm. 2018 Dec 03; 15(12):5602-5614.
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Glucuronidation: driving factors and their impact on glucuronide disposition. Drug Metab Rev. 2017 05; 49(2):105-138.
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Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Regulate the Disposition of Acacetin Glucuronides. Pharm Res. 2017 Jul; 34(7):1402-1415.
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Transport-Glucuronidation Classification System and PBPK Modeling: New Approach To Predict the Impact of Transporters on Disposition of Glucuronides. Mol Pharm. 2017 09 05; 14(9):2884-2898.
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Metabolic Disposition of Luteolin Is Mediated by the Interplay of UDP-Glucuronosyltransferases and Catechol-O-Methyltransferases in Rats. Drug Metab Dispos. 2017 03; 45(3):306-315.
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Establishment and use of new MDCK II cells overexpressing both UGT1A1 and MRP2 to characterize flavonoid metabolism via the glucuronidation pathway. Mol Nutr Food Res. 2016 Sep; 60(9):1967-83.