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Rashim Singh

TitleAssociate Professor
InstitutionUniversity of Houston
DepartmentPharmacological and Pharmaceutical Sciences
Address4800 Calhoun Rd
Houston TX 77004
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Zheng Z, ?aponjac VT, Singh R, Chen J, Srinual S, Yin T, Sun R, Hu M. Correction: Fecal SN-38 Content as a Surrogate Predictor of Intestinal SN-38 Exposure and Associated Irinotecan-induced Severe Delayed-Onset Diarrhea by a Novel Use of the Spectrofluorimetric Method. Pharm Res. 2024 Oct; 41(10):2075. PMID: 39349694.
      Citations:    Fields:    
    2. Zheng Z, ?aponjac VT, Singh R, Chen J, Srinual S, Yin T, Sun R, Hu M. Fecal SN-38 Content as a Surrogate Predictor of Intestinal SN-38 Exposure and Associated Irinotecan-induced Severe Delayed-Onset Diarrhea by a Novel Use of the Spectrofluorimetric Method. Pharm Res. 2024 Sep; 41(9):1855-1867. PMID: 39138788.
      Citations:    Fields:    Translation:Animals
    3. Lethe MCL, Bui D, Hu M, Wang X, Singh R, Chan CTY. Discovering New Substrates of a UDP-Glycosyltransferase with a High-Throughput Method. Int J Mol Sci. 2024 Feb 27; 25(5). PMID: 38473971; PMCID: PMC10931590.
      Citations:    Fields:    Translation:Animals
    4. Zheng Z, Du T, Gao S, Yin T, Li L, Zhu L, Singh R, Sun R, Hu M. Optimized rat models better mimic patients with irinotecan-induced severe diarrhea. Toxicol Mech Methods. 2024 Jun; 34(5):572-583. PMID: 38390772; PMCID: PMC11095999.
      Citations: 1     Fields:    Translation:HumansAnimals
    5. Bui D, McWilliams LA, Wu L, Zhou H, Wong SJ, You M, Chow DS, Singh R, Hu M. Pharmacokinetic Basis for Using Saliva Matrine Concentrations as a Clinical Compliance Monitoring in Antitumor B Chemoprevention Trials in Humans. Cancers (Basel). 2022 Dec 23; 15(1). PMID: 36612086; PMCID: PMC9817974.
      Citations: 2     
    6. Tao G, Dagher F, Li L, Singh R, Hu M, Ghose R. Corrigendum to "Irinotecan decreases intestinal UDP-glucuronosyltransferase (UGT) 1A1 via TLR4/MyD88 pathway prior to the onset of diarrhea" [Food Chem. Toxicol. 166 (2022) 113246]. Food Chem Toxicol. 2023 Jan; 171:113547. PMID: 36495622.
      Citations:    Fields:    
    7. Gao S, Sun R, Singh R, Yu So S, Chan CTY, Savidge T, Hu M. The role of gut microbial ?-glucuronidase in drug disposition and development. Drug Discov Today. 2022 10; 27(10):103316. PMID: 35820618; PMCID: PMC9717552.
      Citations: 8     Fields:    Translation:Animals
    8. Tao G, Dagher F, Li L, Singh R, Hu M, Ghose R. Irinotecan decreases intestinal UDP-glucuronosyltransferase (UGT) 1A1 via TLR4/MyD88 pathway prior to the onset of diarrhea. Food Chem Toxicol. 2022 Aug; 166:113246. PMID: 35728726.
      Citations:    Fields:    Translation:Animals
    9. Bui D, Yin T, Duan S, Wei B, Yang P, Wong SJ, You M, Singh R, Hu M. Pharmacokinetic Characterization and Bioavailability Barrier for the Key Active Components of Botanical Drug Antitumor B (ATB) in Mice for Chemoprevention of Oral Cancer. J Nat Prod. 2021 09 24; 84(9):2486-2495. PMID: 34463097; PMCID: PMC10607708.
      Citations: 2     Fields:    Translation:AnimalsCells
    10. Tu Y, Wang L, Rong Y, Tam V, Yin T, Gao S, Singh R, Hu M. Hepatoenteric recycling is a new disposition mechanism for orally administered phenolic drugs and phytochemicals in rats. Elife. 2021 07 01; 10. PMID: 34196607; PMCID: PMC8248983.
      Citations: 5     Fields:    Translation:Animals
    11. Bui D, Li L, Yin T, Wang X, Gao S, You M, Singh R, Hu M. Pharmacokinetic and Metabolic Profiling of Key Active Components of Dietary Supplement Magnolia officinalis Extract for Prevention against Oral Carcinoma. J Agric Food Chem. 2020 Jun 17; 68(24):6576-6587. PMID: 32348135; PMCID: PMC7604171.
      Citations: 6     Fields:    Translation:HumansAnimals
    12. Singh R, Lu R, Hu M. Flavonoids interference in common protein assays: Effect of position and degree of hydroxyl substitution. Anal Biochem. 2020 05 15; 597:113644. PMID: 32105737; PMCID: PMC9154353.
      Citations: 1     Fields:    Translation:Animals
    13. Yun C, Dashwood WM, Kwong LN, Gao S, Yin T, Ling Q, Singh R, Dashwood RH, Hu M. Accurate quantification of PGE2 in the polyposis in rat colon (Pirc) model by surrogate analyte-based UPLC-MS/MS. J Pharm Biomed Anal. 2018 Jan 30; 148:42-50. PMID: 28957718; PMCID: PMC5698167.
      Citations: 5     Fields:    Translation:Animals
    14. Yang G, Ge S, Singh R, Basu S, Shatzer K, Zen M, Liu J, Tu Y, Zhang C, Wei J, Shi J, Zhu L, Liu Z, Wang Y, Gao S, Hu M. Glucuronidation: driving factors and their impact on glucuronide disposition. Drug Metab Rev. 2017 05; 49(2):105-138. PMID: 28266877; PMCID: PMC7660525.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    15. Singh R, Wu B, Tang L, Hu M. Uridine diphosphate glucuronosyltransferase isoform-dependent regiospecificity of glucuronidation of flavonoids. J Agric Food Chem. 2011 Jul 13; 59(13):7452-64. PMID: 21413806; PMCID: PMC3391414.
      Citations: 17     Fields:    Translation:Humans
    16. Wu B, Morrow JK, Singh R, Zhang S, Hu M. Three-dimensional quantitative structure-activity relationship studies on UGT1A9-mediated 3-O-glucuronidation of natural flavonols using a pharmacophore-based comparative molecular field analysis model. J Pharmacol Exp Ther. 2011 Feb; 336(2):403-13. PMID: 21068207; PMCID: PMC3033718.
      Citations: 18     Fields:    Translation:Humans
    17. Singh R, Wu B, Tang L, Liu Z, Hu M. Identification of the position of mono-O-glucuronide of flavones and flavonols by analyzing shift in online UV spectrum (lambdamax) generated from an online diode array detector. J Agric Food Chem. 2010 Sep 08; 58(17):9384-95. PMID: 20687611; PMCID: PMC3404750.
      Citations: 23     Fields:    
    18. Yang Z, Zhu W, Gao S, Xu H, Wu B, Kulkarni K, Singh R, Tang L, Hu M. Simultaneous determination of genistein and its four phase II metabolites in blood by a sensitive and robust UPLC-MS/MS method: Application to an oral bioavailability study of genistein in mice. J Pharm Biomed Anal. 2010 Sep 21; 53(1):81-9. PMID: 20378296; PMCID: PMC3397253.
      Citations: 23     Fields:    Translation:AnimalsCells
    19. Xu H, Kulkarni KH, Singh R, Yang Z, Wang SW, Tam VH, Hu M. Disposition of naringenin via glucuronidation pathway is affected by compensating efflux transporters of hydrophilic glucuronides. Mol Pharm. 2009 Nov-Dec; 6(6):1703-15. PMID: 19736994; PMCID: PMC2941777.
      Citations: 17     Fields:    Translation:AnimalsCells
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