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Wei Wang

TitleAssistant Professor
InstitutionUniversity of Houston
DepartmentPharmacological and Pharmaceutical Sciences
Address4800 Calhoun Rd
Houston TX 77004
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Wang W, Aguilar M, Datta S, Alley A, Tadesse M, Wang X, Gao X, Zhang R. Dual inhibitor of MDM2 and NFAT1 for experimental therapy of breast cancer: in vitro and in vivo anticancer activities and newly discovered effects on cancer metabolic pathways. Front Pharmacol. 2025; 16:1531667. PMID: 40046748; PMCID: PMC11879958.
      Citations:    
    2. Zhu L, Huang Y, Jin J, Zou R, Zuo R, Luo Y, Song Z, Dai L, Zhang M, Chen Q, Wang Y, Wang W, He R, Chen Y. Cerebral endothelial 3-mercaptopyruvate sulfurtransferase improves ischemia-induced cognitive impairment via interacting with protein phosphatase 2A. Acta Pharm Sin B. 2025 Jan; 15(1):314-330. PMID: 40041885; PMCID: PMC11873647.
      Citations:    
    3. Wang W, Albadari N, Du Y, Fowler JF, Sang HT, Xian W, McKeon F, Li W, Zhou J, Zhang R. MDM2 Inhibitors for Cancer Therapy: The Past, Present, and Future. Pharmacol Rev. 2024 May 02; 76(3):414-453. PMID: 38697854; PMCID: PMC11068841.
      Citations: 8     Fields:    Translation:HumansAnimals
    4. Wang D, Tang M, Zhang P, Yang K, Huang L, Wu M, Shen Q, Yue J, Wang W, Gong Y, Warner M, Dai L, He H, Yang Z, Gustafsson JA, Zhou S. Activation of ER? hijacks the splicing machinery to trigger R-loop formation in triple-negative breast cancer. Proc Natl Acad Sci U S A. 2024 Mar 26; 121(13):e2306814121. PMID: 38513102; PMCID: PMC10990146.
      Citations: 2     Fields:    Translation:HumansCells
    5. Wang W, Du Y, Datta S, Fowler JF, Sang HT, Albadari N, Li W, Foster J, Zhang R. Targeting the MYCN-MDM2 pathways for cancer therapy: Are they druggable? Genes Dis. 2025 Mar; 12(2):101156. PMID: 39802403; PMCID: PMC11719324.
      Citations:    
    6. Han D, Wang W, Jeon JH, Shen T, Huang X, Yi P, Dong B, Yang F. Cooperative activation of PDK1 and AKT by MAPK4 enhances cancer growth and resistance to therapy. PLoS Biol. 2023 Aug; 21(8):e3002227. PMID: 37531320; PMCID: PMC10395914.
      Citations:    Fields:    Translation:HumansCells
    7. Terrell JR, Tang S, Faniyi OO, Jeong IH, Yin J, Nijampatnam B, Velu SE, Wang W, Zhang R, Luo M. Structural studies of antitumor compounds that target the RING domain of MDM2. Protein Sci. 2022 Aug; 31(8):e4367. PMID: 35900024; PMCID: PMC9301682.
      Citations: 2     Fields:    Translation:AnimalsCells
    8. Kaluz S, Zhang Q, Kuranaga Y, Yang H, Osuka S, Bhattacharya D, Devi NS, Mun J, Wang W, Zhang R, Goodman MM, Grossniklaus HE, Van Meir EG. Targeting HIF-activated collagen prolyl 4-hydroxylase expression disrupts collagen deposition and blocks primary and metastatic uveal melanoma growth. Oncogene. 2021 Aug; 40(33):5182-5191. PMID: 34218269; PMCID: PMC8887959.
      Citations: 9     Fields:    
    9. Prevolnik Rupel V, Jagger B, Fialho LS, Chadderton LM, Gintner T, Arntz A, Baltzersen ÅL, Blazdell J, van Busschbach J, Cencelli M, Chanen A, Delvaux C, van Gorp F, Langford L, McKenna B, Moran P, Pacheco K, Sharp C, Wang W, Wright K, Crawford MJ. Standard set of patient-reported outcomes for personality disorder. Qual Life Res. 2021 Dec; 30(12):3485-3500. PMID: 34075531; PMCID: PMC8602216.
      Citations: 9     Fields:    Translation:Humans
    10. Ibrahim Al-Obaide MA, Arutla V, Bacolod MD, Wang W, Zhang R, Srivenugopal KS. Genomic Space of MGMT in Human Glioma Revisited: Novel Motifs, Regulatory RNAs, NRF1, 2, and CTCF Involvement in Gene Expression. Int J Mol Sci. 2021 Mar 02; 22(5). PMID: 33801310; PMCID: PMC7958331.
      Citations: 4     Fields:    Translation:HumansCells
    11. Qin L, Chen CP, Wang W, Chen H. How migrants get integrated in urban China - The impact of health insurance. Soc Sci Med. 2021 Mar; 272:113700. PMID: 33497940.
      Citations: 13     Fields:    Translation:Humans
    12. Wang W, Wang X, Rajaei M, Youn JY, Zafar A, Deokar H, Buolamwini JK, Yang J, Foster JH, Zhou J, Zhang R. Targeting MDM2 for Neuroblastoma Therapy: In Vitro and In Vivo Anticancer Activity and Mechanism of Action. Cancers (Basel). 2020 Dec 05; 12(12). PMID: 33291373; PMCID: PMC7762001.
      Citations: 7     
    13. Zafar A, Wang W, Liu G, Wang X, Xian W, McKeon F, Foster J, Zhou J, Zhang R. Molecular targeting therapies for neuroblastoma: Progress and challenges. Med Res Rev. 2021 03; 41(2):961-1021. PMID: 33155698; PMCID: PMC7906923.
      Citations: 140     Fields:    Translation:HumansCells
    14. Zafar A, Wang W, Liu G, Xian W, McKeon F, Zhou J, Zhang R. Targeting the p53-MDM2 pathway for neuroblastoma therapy: Rays of hope. Cancer Lett. 2021 01 01; 496:16-29. PMID: 33007410; PMCID: PMC8351219.
      Citations: 49     Fields:    Translation:HumansAnimals
    15. Ashraf-Uz-Zaman M, Shahi S, Akwii R, Sajib MS, Farshbaf MJ, Kallem RR, Putnam W, Wang W, Zhang R, Alvina K, Trippier PC, Mikelis CM, German NA. Design, synthesis and structure-activity relationship study of novel urea compounds as FGFR1 inhibitors to treat metastatic triple-negative breast cancer. Eur J Med Chem. 2021 Jan 01; 209:112866. PMID: 33039722; PMCID: PMC7744370.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    16. Huang S, Zhou N, Zhao L, Gimple RC, Ahn YH, Zhang P, Wang W, Shao B, Yang J, Zhang Q, Zhao S, Jiang X, Chen Z, Zeng Y, Hu H, Gustafsson JÅ, Zhou S. Pharmacological Activation of Estrogen Receptor Beta Overcomes Tumor Resistance to Immune Checkpoint Blockade Therapy. iScience. 2020 Sep 25; 23(9):101458. PMID: 32861994; PMCID: PMC7476860.
      Citations: 11     
    17. Punganuru SR, Artula V, Zhao W, Rajaei M, Deokar H, Zhang R, Buolamwini JK, Srivenugopal KS, Wang W. Targeted Brain Tumor Therapy by Inhibiting the MDM2 Oncogene: In Vitro and In Vivo Antitumor Activity and Mechanism of Action. Cells. 2020 Jul 01; 9(7). PMID: 32630235; PMCID: PMC7408354.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    18. Wang W, Zafar A, Rajaei M, Zhang R. Two Birds with One Stone: NFAT1-MDM2 Dual Inhibitors for Cancer Therapy. Cells. 2020 05 09; 9(5). PMID: 32397368; PMCID: PMC7291050.
      Citations: 7     Fields:    Translation:HumansAnimals
    19. Rao W, Wang S, Duleba M, Niroula S, Goller K, Xie J, Mahalingam R, Neupane R, Liew AA, Vincent M, Okuda K, O'Neal WK, Boucher RC, Dickey BF, Wechsler ME, Ibrahim O, Engelhardt JF, Mertens TCJ, Wang W, Jyothula SSK, Crum CP, Karmouty-Quintana H, Parekh KR, Metersky ML, McKeon FD, Xian W. Regenerative Metaplastic Clones in COPD Lung Drive Inflammation and Fibrosis. Cell. 2020 05 14; 181(4):848-864.e18. PMID: 32298651; PMCID: PMC7294989.
      Citations: 61     Fields:    
    20. Wang W, Hu B, Qin JJ, Cheng J, Li X, Rajaei M, Fan J, Yang XR, Zhang R. Corrigendum to "A novel inhibitor of MDM2 oncogene blocks metastasis of hepatocellular carcinoma and overcomes chemoresistance" [Genes Dis 694 (2019) 419-430]. Genes Dis. 2020 03; 7(1):160-161. PMID: 32181287; PMCID: PMC7063448.
      Citations:    
    21. Wang W, Qin JJ, Rajaei M, Li X, Yu X, Hunt C, Zhang R. Targeting MDM2 for novel molecular therapy: Beyond oncology. Med Res Rev. 2020 05; 40(3):856-880. PMID: 31587329; PMCID: PMC7131869.
      Citations: 41     Fields:    Translation:HumansAnimals
    22. Wang W, Hu B, Qin JJ, Cheng JW, Li X, Rajaei M, Fan J, Yang XR, Zhang R. A novel inhibitor of MDM2 oncogene blocks metastasis of hepatocellular carcinoma and overcomes chemoresistance. Genes Dis. 2019 Dec; 6(4):419-430. PMID: 31832522; PMCID: PMC6889017.
      Citations: 25     
    23. Wang W, Cheng JW, Qin JJ, Hu B, Li X, Nijampatnam B, Velu SE, Fan J, Yang XR, Zhang R. MDM2-NFAT1 dual inhibitor, MA242: Effective against hepatocellular carcinoma, independent of p53. Cancer Lett. 2019 09 10; 459:156-167. PMID: 31181320; PMCID: PMC6650270.
      Citations: 26     Fields:    Translation:HumansCells
    24. Sun R, Basu S, Zeng M, Sunsong R, Li L, Ghose R, Wang W, Liu Z, Hu M, Gao S. Xiao-Chai-Hu-Tang (XCHT) Intervening Irinotecan's Disposition: The Potential of XCHT in Alleviating Irinotecan-Induced Diarrhea. Curr Cancer Drug Targets. 2019; 19(7):551-560. PMID: 31509102.
      Citations: 3     Fields:    Translation:Animals
    25. Leonard BC, Jalilian I, Raghunathan VK, Wang W, Jun AS, Murphy CJ, Thomasy SM. Biomechanical changes to Descemet's membrane precede endothelial cell loss in an early-onset murine model of Fuchs endothelial corneal dystrophy. Exp Eye Res. 2019 Mar; 180:18-22. PMID: 30471280; PMCID: PMC6389414.
      Citations: 13     Fields:    Translation:Animals
    26. Deokar H, Deokar M, Wang W, Zhang R, Buolamwini JK. QSAR Studies of New Pyrido[3,4-b]indole Derivatives as Inhibitors of Colon and Pancreatic Cancer Cell Proliferation. Med Chem Res. 2018 Dec; 27(11-12):2466-2481. PMID: 31360052; PMCID: PMC6662939.
      Citations: 6     
    27. Wang W, Qin JJ, Voruganti S, Nijampatnam B, Velu SE, Ruan KH, Hu M, Zhou J, Zhang R. Discovery and Characterization of Dual Inhibitors of MDM2 and NFAT1 for Pancreatic Cancer Therapy. Cancer Res. 2018 10 01; 78(19):5656-5667. PMID: 30217928; PMCID: PMC6435280.
      Citations: 27     Fields:    Translation:AnimalsCells
    28. Wang W, Qin JJ, Li X, Tao G, Wang Q, Wu X, Zhou J, Zi X, Zhang R. Prevention of prostate cancer by natural product MDM2 inhibitor GS25: in vitro and in vivo activities and molecular mechanisms. Carcinogenesis. 2018 07 30; 39(8):1026-1036. PMID: 29762656; PMCID: PMC6067121.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    29. Qin JJ, Li X, Hunt C, Wang W, Wang H, Zhang R. Natural products targeting the p53-MDM2 pathway and mutant p53: Recent advances and implications in cancer medicine. Genes Dis. 2018 Sep; 5(3):204-219. PMID: 30320185; PMCID: PMC6176154.
      Citations: 43     
    30. Zhao L, Huang S, Mei S, Yang Z, Xu L, Zhou N, Yang Q, Shen Q, Wang W, Le X, Lau WB, Lau B, Wang X, Yi T, Zhao X, Wei Y, Warner M, Gustafsson J?, Zhou S. Pharmacological activation of estrogen receptor beta augments innate immunity to suppress cancer metastasis. Proc Natl Acad Sci U S A. 2018 04 17; 115(16):E3673-E3681. PMID: 29592953; PMCID: PMC5910874.
      Citations: 34     Fields:    Translation:AnimalsCells
    31. Qin JJ, Wang W, Li X, Deokar H, Buolamwini JK, Zhang R. Inhibiting ?-Catenin by ?-Carboline-Type MDM2 Inhibitor for Pancreatic Cancer Therapy. Front Pharmacol. 2018; 9:5. PMID: 29387014; PMCID: PMC5776119.
      Citations: 15     
    32. Qin JJ, Li X, Wang W, Zi X, Zhang R. Targeting the NFAT1-MDM2-MDMX Network Inhibits the Proliferation and Invasion of Prostate Cancer Cells, Independent of p53 and Androgen. Front Pharmacol. 2017; 8:917. PMID: 29311926; PMCID: PMC5735069.
      Citations: 21     
    33. Qin JJ, Wang W, Zhang R. Experimental Therapy of Advanced Breast Cancer: Targeting NFAT1-MDM2-p53 Pathway. Prog Mol Biol Transl Sci. 2017; 151:195-216. PMID: 29096894; PMCID: PMC6663080.
      Citations: 11     Fields:    Translation:HumansCells
    34. Xie S, Liu C, Obermayer K, Zhu F, Wang L, Xie X, Wang W. Stimulator Selection in SSVEP-Based Spatial Selective Attention Study. Comput Intell Neurosci. 2016; 2016:6410718. PMID: 28044073; PMCID: PMC5156793.
      Citations: 3     Fields:    Translation:Humans
    35. Wang W, Kennedy R, Lazer D, Ramakrishnan N. Growing pains for global monitoring of societal events. Science. 2016 Sep 30; 353(6307):1502-1503. PMID: 27708093.
      Citations: 9     Fields:    Translation:Humans
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