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Yu Liu

TitleAssistant Professor
InstitutionUniversity of Houston
DepartmentBiology and Biochemistry
Address4800 Calhoun Rd
Houston TX 77004
Phone713-743-8173
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Xian W, Wang S, Xie J, Yamamoto Y, Khorrami M, Zhang Y, Montes RC, Desales C, Khorrami M, Mory Z, Hoffman A, Su A, Nguyen C, Davies PJA, Stephan C, Pan S, Wu W, Liu Y, Siegelman J, Waters RE, Ross WA, Song S, Metersky M, Beer DG, Crum CP, Stewart AJ, Vincent M, Russell R, Izard RA, Ho KY, Lai JH, Bachovchin WW, Ajani JA, McKeon FD. Evolution of Esophageal Adenocarcinoma from Precursor Lesion Stem Cells. Gastroenterology. 2025 Mar 14. PMID: 40090599.
      Citations:    
    2. Wang W, Albadari N, Du Y, Fowler JF, Sang HT, Xian W, McKeon F, Li W, Zhou J, Zhang R. MDM2 Inhibitors for Cancer Therapy: The Past, Present, and Future. Pharmacol Rev. 2024 May 02; 76(3):414-453. PMID: 38697854; PMCID: PMC11068841.
      Citations: 8     Fields:    Translation:HumansAnimals
    3. Wang S, Niroula S, Hoffman A, Khorrami M, Khorrami M, Yuan F, Gasser GN, Choi S, Liu B, Li J, Metersky ML, Vincent M, Crum CP, Boucher RC, Karmouty-Quintana H, Huang HJ, Sheshadri A, Dickey BF, Parekh KR, Engelhardt JF, McKeon FD, Xian W. Inflammatory Activity of Epithelial Stem Cell Variants from Cystic Fibrosis Lungs Is Not Resolved by CFTR Modulators. Am J Respir Crit Care Med. 2023 11 01; 208(9):930-943. PMID: 37695863; PMCID: PMC10870857.
      Citations: 5     Fields:    Translation:HumansAnimals
    4. Wang S, Rao W, Hoffman A, Lin J, Li J, Lin T, Liew AA, Vincent M, Mertens TCJ, Karmouty-Quintana H, Crum CP, Metersky ML, Schwartz DA, Davies PJA, Stephan C, Jyothula SSK, Sheshadri A, Suarez EE, Huang HJ, Engelhardt JF, Dickey BF, Parekh KR, McKeon FD, Xian W. Cloning a profibrotic stem cell variant in idiopathic pulmonary fibrosis. Sci Transl Med. 2023 04 26; 15(693):eabp9528. PMID: 37099633; PMCID: PMC10794039.
      Citations: 5     Fields:    Translation:HumansCells
    5. Fan Y, Li Y, Yao X, Jin J, Scott A, Liu B, Wang S, Huo L, Wang Y, Wang R, Pool Pizzi M, Ma L, Shao S, Sewastjanow-Silva M, Waters R, Chatterjee D, Liu B, Shanbhag N, Peng G, Calin GA, Mazur PK, Hanash SM, Ishizawa J, Hirata Y, Nagano O, Wang Z, Wang L, Xian W, McKeon F, Ajani JA, Song S. Epithelial SOX9 drives progression and metastases of gastric adenocarcinoma by promoting immunosuppressive tumour microenvironment. Gut. 2023 04; 72(4):624-637. PMID: 36002248.
      Citations: 22     Fields:    Translation:Humans
    6. Zafar A, Wang W, Liu G, Wang X, Xian W, McKeon F, Foster J, Zhou J, Zhang R. Molecular targeting therapies for neuroblastoma: Progress and challenges. Med Res Rev. 2021 03; 41(2):961-1021. PMID: 33155698; PMCID: PMC7906923.
      Citations: 140     Fields:    Translation:HumansCells
    7. Zafar A, Wang W, Liu G, Xian W, McKeon F, Zhou J, Zhang R. Targeting the p53-MDM2 pathway for neuroblastoma therapy: Rays of hope. Cancer Lett. 2021 01 01; 496:16-29. PMID: 33007410; PMCID: PMC8351219.
      Citations: 49     Fields:    Translation:HumansAnimals
    8. Rao W, Niroula S, Wang S, Vincent M, McKeon F, Xian W. Protocol for Cloning Epithelial Stem Cell Variants from Human Lung. STAR Protoc. 2020 09 18; 1(2). PMID: 33015646; PMCID: PMC7529324.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    9. Mckeon F, Xian W. Mystery Solving: Acid Reflux and Cell Mobility in Barrett's Esophagus and Esophageal Adenocarcinoma. Cell Mol Gastroenterol Hepatol. 2020; 10(3):639-640. PMID: 32598898; PMCID: PMC7474153.
      Citations:    Fields:    Translation:Humans
    10. Rao W, Wang S, Duleba M, Niroula S, Goller K, Xie J, Mahalingam R, Neupane R, Liew AA, Vincent M, Okuda K, O'Neal WK, Boucher RC, Dickey BF, Wechsler ME, Ibrahim O, Engelhardt JF, Mertens TCJ, Wang W, Jyothula SSK, Crum CP, Karmouty-Quintana H, Parekh KR, Metersky ML, McKeon FD, Xian W. Regenerative Metaplastic Clones in COPD Lung Drive Inflammation and Fibrosis. Cell. 2020 05 14; 181(4):848-864.e18. PMID: 32298651; PMCID: PMC7294989.
      Citations: 61     Fields:    
    11. Duleba M, Yamamoto Y, Neupane R, Rao W, Xie J, Qi Y, Liew AA, Niroula S, Zhang Y, Mahalingam R, Wang S, Goller K, Ajani JA, Vincent M, Ho KY, Hou JK, Hyams JS, Sylvester FA, Crum CP, McKeon F, Xian W. Cloning of ground-state intestinal stem cells from endoscopic biopsy samples. Nat Protoc. 2020 05; 15(5):1612-1627. PMID: 32238950.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    12. Xian W, McKeon F. Microenvironment meets lineage complexity in junctional tumorigenesis. Nat Commun. 2019 08 23; 10(1):3829. PMID: 31444324; PMCID: PMC6707302.
      Citations: 1     Fields:    Translation:Humans
    13. Duleba M, Mahalingam R, Liew AA, Qi Y, Neupane R, Vincent M, Agarwal S, Sylvester FA, Hyams JS, Ho KY, Hou JK, McKeon F, Xian W. Unlimited expansion of intestinal stem cells from a wide range of ages. Integr Mol Med. 2019 Aug; 6(4). PMID: 31463081; PMCID: PMC6713279.
      Citations: 1     
    14. Adebiyi MG, Zhao Z, Ye Y, Manalo J, Hong Y, Lee CC, Xian W, McKeon F, Culp-Hill R, D' Alessandro A, Kellems RE, Yoo SH, Han L, Xia Y. Circadian period 2: a missing beneficial factor in sickle cell disease by lowering pulmonary inflammation, iron overload, and mortality. FASEB J. 2019 09; 33(9):10528-10537. PMID: 31260634; PMCID: PMC6988849.
      Citations: 2     Fields:    Translation:Animals
    15. Xian W, Duleba M, Zhang Y, Yamamoto Y, Ho KY, Crum C, McKeon F. The Cellular Origin of Barrett's Esophagus and Its Stem Cells. Adv Exp Med Biol. 2019; 1123:55-69. PMID: 31016595.
      Citations: 6     Fields:    Translation:HumansCells
    16. Xian W, Duleba M, Qi Y, Mahalingam R, Vincent M, McKeon F. Ground-State Stem Cells: A Novel Approach for Adult Stem Cell Research. J Pediatr Pediatr Med. 2018; 2(6):7-10. PMID: 30957106; PMCID: PMC6448798.
      Citations:    
    17. Xian W, Duleba M, Yamamoto Y, Vincent M, McKeon F. Biobanking Organoids or Ground-State Stem Cells? J Clin Med. 2018 Dec 16; 7(12). PMID: 30558346; PMCID: PMC6306851.
      Citations:    
    18. Xian W, McKeon F. Demise of lung transplants: exposing critical gaps in understanding lung stem cells. J Thorac Dis. 2018 Apr; 10(Suppl 9):S1016-S1019. PMID: 29849224; PMCID: PMC5949424.
      Citations:    
    19. Xian W, McKeon F. TAp63 as a guardian of female germ line integrity. Nat Struct Mol Biol. 2018 03; 25(3):201-202. PMID: 29507403.
      Citations: 4     Fields:    Translation:HumansCells
    20. Spechler SJ, Merchant JL, Wang TC, Chandrasoma P, Fox JG, Genta RM, Goldenring JR, Hayakawa Y, Kuipers EJ, Lund PK, McKeon F, Mills JC, Odze RD, Peek RM, Pham T, Que J, Rustgi AK, Shaheen NJ, Shivdasani RA, Souza RF, Storz P, Todisco A, Wang DH, Wright NA. A Summary of the 2016 James W. Freston Conference of the American Gastroenterological Association: Intestinal Metaplasia in the Esophagus and Stomach: Origins, Differences, Similarities and Significance. Gastroenterology. 2017 Jul; 153(1):e6-e13. PMID: 28583825; PMCID: PMC5828164.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    21. Xian W, McKeon F. Barrett's Stem Cells as a Unique and Targetable?Entity. Cell Mol Gastroenterol Hepatol. 2017 Jul; 4(1):161-164. PMID: 28593188; PMCID: PMC5454139.
      Citations: 3     Fields:    
    22. Yamamoto Y, Wang X, Bertrand D, Kern F, Zhang T, Duleba M, Srivastava S, Khor CC, Hu Y, Wilson LH, Blaszyk H, Rolshud D, Teh M, Liu J, Howitt BE, Vincent M, Crum CP, Nagarajan N, Ho KY, McKeon F, Xian W. Mutational spectrum of Barrett's stem cells suggests paths to initiation of a precancerous lesion. Nat Commun. 2016 Jan 19; 7:10380. PMID: 26783136; PMCID: PMC4735693.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    23. Yamamoto Y, Ning G, Howitt BE, Mehra K, Wu L, Wang X, Hong Y, Kern F, Wei TS, Zhang T, Nagarajan N, Basuli D, Torti S, Brewer M, Choolani M, McKeon F, Crum CP, Xian W. In vitro and in vivo correlates of physiological and neoplastic human Fallopian tube stem cells. J Pathol. 2016 Mar; 238(4):519-530. PMID: 26415052; PMCID: PMC4895925.
      Citations: 49     Fields:    Translation:HumansCells
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