In Situ Nick-End Labeling
"In Situ Nick-End Labeling" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An in situ method for detecting areas of DNA which are nicked during APOPTOSIS. Terminal deoxynucleotidyl transferase is used to add labeled dUTP, in a template-independent manner, to the 3 prime OH ends of either single- or double-stranded DNA. The terminal deoxynucleotidyl transferase nick end labeling, or TUNEL, assay labels apoptosis on a single-cell level, making it more sensitive than agarose gel electrophoresis for analysis of DNA FRAGMENTATION.
| Descriptor ID |
D020287
|
| MeSH Number(s) |
E05.393.475
|
| Concept/Terms |
In Situ Nick-End Labeling- In Situ Nick-End Labeling
- TUNEL
- Nick-End Labeling, In Situ
- In Situ Nick End Labelling
- In Situ Nick End Labeling
- In Situ Nick End-Labelling
- In Situ Nick-End Labelling
- Nick End-Labeling, In Situ
- Nick End Labeling, In Situ
- Nick End-Labelling, In Situ
- Nick End Labelling, In Situ
- Nick-End Labelling, In Situ
- In Situ Nick End-Labeling
|
Below are MeSH descriptors whose meaning is more general than "In Situ Nick-End Labeling".
Below are MeSH descriptors whose meaning is more specific than "In Situ Nick-End Labeling".
This graph shows the total number of publications written about "In Situ Nick-End Labeling" by people in this website by year, and whether "In Situ Nick-End Labeling" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "In Situ Nick-End Labeling" by people in Profiles.
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Sex differences in hippocampal damage, cognitive impairment, and trophic factor expression in an animal model of an alcohol use disorder. Brain Struct Funct. 2018 Jan; 223(1):195-210.
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Uric acid stones in the urinary bladder of aryl hydrocarbon receptor (AhR) knockout mice. Proc Natl Acad Sci U S A. 2012 Jan 24; 109(4):1122-6.
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Biomimetic microenvironment modulates neural stem cell survival, migration, and differentiation. Tissue Eng Part A. 2010 Dec; 16(12):3747-58.
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In vitro neural injury model for optimization of tissue-engineered constructs. J Neurosci Res. 2007 Dec; 85(16):3642-51.
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Strain rate-dependent induction of reactive astrogliosis and cell death in three-dimensional neuronal-astrocytic co-cultures. Brain Res. 2007 Jul 16; 1158:103-15.