Ming Hu to Humans
This is a "connection" page, showing publications Ming Hu has written about Humans.
Connection Strength
1.663
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Optimized rat models better mimic patients with irinotecan-induced severe diarrhea. Toxicol Mech Methods. 2024 Jun; 34(5):572-583.
Score: 0.089
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Where will Medicines that Serve the Global South and Economically Disadvantaged People Come From? Curr Drug Metab. 2024; 25(1):1.
Score: 0.088
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Reduction of systemic exposure and side effects by intra-articular injection of anti-inflammatory agents for osteoarthritis: what is the safer strategy? J Drug Target. 2023 07; 31(6):596-611.
Score: 0.085
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Development of Rofecoxib-Based Fluorescent Probes and Investigations on Their Solvatochromism, AIE Activity, Mechanochromism, and COX-2-Targeted Bioimaging. Anal Chem. 2021 09 07; 93(35):11991-12000.
Score: 0.075
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One-Step Transformation from Rofecoxib to a COX-2 NIR Probe for Human Cancer Tissue/Organoid Targeted Bioimaging. ACS Appl Bio Mater. 2021 03 15; 4(3):2723-2731.
Score: 0.072
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Overexpression of MRP3 in HeLa-UGT1A9 Cells Enhances Glucuronidation Capability of the Cells. Curr Drug Metab. 2021; 22(10):772-783.
Score: 0.071
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Rapid intestinal glucuronidation and hepatic glucuronide recycling contributes significantly to the enterohepatic circulation of icaritin and its glucuronides in vivo. Arch Toxicol. 2020 Nov; 94(11):3737-3749.
Score: 0.070
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Pharmacokinetic and Metabolic Profiling of Key Active Components of Dietary Supplement Magnolia officinalis Extract for Prevention against Oral Carcinoma. J Agric Food Chem. 2020 Jun 17; 68(24):6576-6587.
Score: 0.069
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Bioavailability of Polyphenols and Flavonoids in the Era of Precision Medicine. Mol Pharm. 2017 09 05; 14(9):2861-2863.
Score: 0.057
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Inhibition of Human UGT1A1-Mediated Bilirubin Glucuronidation by Polyphenolic Acids Impact Safety of Popular Salvianolic Acid A/B-Containing Drugs and Herbal Products. Mol Pharm. 2017 Sep 05; 14(9):2952-2966.
Score: 0.056
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LC-MS/MS quantification of sulfotransferases is better than conventional immunogenic methods in determining human liver SULT activities: implication in precision medicine. Sci Rep. 2017 Jun 20; 7(1):3858.
Score: 0.056
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Glucuronidation: driving factors and their impact on glucuronide disposition. Drug Metab Rev. 2017 05; 49(2):105-138.
Score: 0.056
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Transport-Glucuronidation Classification System and PBPK Modeling: New Approach To Predict the Impact of Transporters on Disposition of Glucuronides. Mol Pharm. 2017 09 05; 14(9):2884-2898.
Score: 0.055
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Establishment and use of new MDCK II cells overexpressing both UGT1A1 and MRP2 to characterize flavonoid metabolism via the glucuronidation pathway. Mol Nutr Food Res. 2016 Sep; 60(9):1967-83.
Score: 0.052
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In?vitro glucuronidation of methyl gallate and pentagalloyl glucopyranose by liver microsomes. Drug Metab Pharmacokinet. 2016 Aug; 31(4):292-303.
Score: 0.052
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Factors Influencing Oral Bioavailability of Thai Mango Seed Kernel Extract and Its Key Phenolic Principles. Molecules. 2015 Nov 30; 20(12):21254-73.
Score: 0.050
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Curcumin Affects Phase II Disposition of Resveratrol Through Inhibiting Efflux Transporters MRP2 and BCRP. Pharm Res. 2016 Mar; 33(3):590-602.
Score: 0.050
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Determination of pharmacokinetics of chrysin and its conjugates in wild-type FVB and Bcrp1 knockout mice using a validated LC-MS/MS method. J Agric Food Chem. 2015 Mar 25; 63(11):2902-10.
Score: 0.048
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Development and validation of an UPLC-MS/MS method for the quantification of ethoxzolamide in blood, brain tissue, and bioequivalent buffers: applications to absorption, brain distribution, and pharmacokinetic studies. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Apr 01; 986-987:54-9.
Score: 0.047
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Pyridopyrimidinones as a new chemotype of calcium dependent protein kinase 1 (CDPK1) inhibitors for Cryptosporidium. Mol Biochem Parasitol. 2024 12; 260:111637.
Score: 0.023
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Herbal Medicines as Adjuvants for the Treatment of Chemotherapy-Induced Diarrhea. Curr Drug Metab. 2023; 24(6):422-433.
Score: 0.021
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SIRT1 inhibition-induced senescence as a strategy to prevent prostate cancer progression. Mol Carcinog. 2022 Jul; 61(7):702-716.
Score: 0.020
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Disordered farnesoid X receptor signaling is associated with liver carcinogenesis in Abcb11-deficient mice. J Pathol. 2021 Dec; 255(4):412-424.
Score: 0.019
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Intestinal Excretion, Intestinal Recirculation, and Renal Tubule Reabsorption Are Underappreciated Mechanisms That Drive the Distribution and Pharmacokinetic Behavior of Small Molecule Drugs. J Med Chem. 2021 Jun 10; 64(11):7045-7059.
Score: 0.018
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy. 2021 Jan; 17(1):1-382.
Score: 0.018
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A randomized, double-blind, placebo-controlled, single and multiple ascending dose Phase 1 study to determine the safety, pharmacokinetics and food and faecal microbiome effects of ibezapolstat administered orally to healthy subjects. J Antimicrob Chemother. 2020 12 01; 75(12):3635-3643.
Score: 0.018
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Potential role of drug metabolizing enzymes in chemotherapy-induced gastrointestinal toxicity and hepatotoxicity. Expert Opin Drug Metab Toxicol. 2020 Nov; 16(11):1109-1124.
Score: 0.017
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Receptor-interacting protein kinase 2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling inhibitors based on a 3,5-diphenyl-2-aminopyridine scaffold. Eur J Med Chem. 2020 Aug 15; 200:112417.
Score: 0.017
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Irinotecan-mediated diarrhea is mainly correlated with intestinal exposure to SN-38: Critical role of gut Ugt. Toxicol Appl Pharmacol. 2020 07 01; 398:115032.
Score: 0.017
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Magnolia extract is effective for the chemoprevention of oral cancer through its ability to inhibit mitochondrial respiration at complex I. Cell Commun Signal. 2020 Apr 07; 18(1):58.
Score: 0.017
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Insight into tartrate inhibition patterns in vitro and in vivo based on cocrystal structure with UDP-glucuronosyltransferase 2B15. Biochem Pharmacol. 2020 Feb; 172:113753.
Score: 0.017
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Potential of herb-drug / herb interactions between substrates and inhibitors of UGTs derived from herbal medicines. Pharmacol Res. 2019 Dec; 150:104510.
Score: 0.016
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Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Determine the Disposition of Esculetin-7-O-Glucuronide and 4-Methylesculetin-7-O-Glucuronide. Drug Metab Dispos. 2019 03; 47(3):203-214.
Score: 0.016
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An update on polyphenol disposition via coupled metabolic pathways. Expert Opin Drug Metab Toxicol. 2019 Feb; 15(2):151-165.
Score: 0.016
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Interplay of Efflux Transporters with Glucuronidation and Its Impact on Subcellular Aglycone and Glucuronide Disposition: A Case Study with Kaempferol. Mol Pharm. 2018 Dec 03; 15(12):5602-5614.
Score: 0.015
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Transcutaneously refillable nanofluidic implant achieves sustained level of tenofovir diphosphate for HIV pre-exposure prophylaxis. J Control Release. 2018 Sep 28; 286:315-325.
Score: 0.015
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An UPLC-MS/MS method for quantifying tetrandrine and its metabolite berbamine in human blood: Application to a human pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Dec 01; 1070:92-96.
Score: 0.014
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Sulfotransferases and Breast Cancer Resistance Protein Determine the Disposition of Calycosin in Vitro and in Vivo. Mol Pharm. 2017 Sep 05; 14(9):2917-2929.
Score: 0.014
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Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Regulate the Disposition of Acacetin Glucuronides. Pharm Res. 2017 Jul; 34(7):1402-1415.
Score: 0.014
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In Vivo Exposure of Kaempferol Is Driven by Phase II Metabolic Enzymes and Efflux Transporters. AAPS J. 2016 Sep; 18(5):1289-1299.
Score: 0.013
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Novel histone deacetylase inhibitors derived from Magnolia officinalis significantly enhance TRAIL-induced apoptosis in non-small cell lung cancer. Pharmacol Res. 2016 Sep; 111:113-125.
Score: 0.013
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Artemisinin and its derivatives can significantly inhibit lung tumorigenesis and tumor metastasis through Wnt/ß-catenin signaling. Oncotarget. 2016 May 24; 7(21):31413-28.
Score: 0.013
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016; 12(1):1-222.
Score: 0.013
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SGLT-1 Transport and Deglycosylation inside Intestinal Cells Are Key Steps in the Absorption and Disposition of Calycosin-7-O-?-d-Glucoside in Rats. Drug Metab Dispos. 2016 Mar; 44(3):283-96.
Score: 0.013
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Species- and gender-dependent differences in the glucuronidation of a flavonoid glucoside and its aglycone determined using expressed UGT enzymes and microsomes. Biopharm Drug Dispos. 2015 Dec; 36(9):622-35.
Score: 0.013
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Reductive metabolism of oxymatrine is catalyzed by microsomal CYP3A4. Drug Des Devel Ther. 2015; 9:5771-83.
Score: 0.012
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Severely Impaired and Dysregulated Cytochrome P450 Expression and Activities in Hepatocellular Carcinoma: Implications for Personalized Treatment in Patients. Mol Cancer Ther. 2015 Dec; 14(12):2874-86.
Score: 0.012
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Developing an activity and absorption-based quality control platform for Chinese traditional medicine: Application to Zeng-Sheng-Ping(Antitumor B). J Ethnopharmacol. 2015 Aug 22; 172:195-201.
Score: 0.012
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UDP-Glucuronosyltransferases 1A6 and 1A9 are the Major Isozymes Responsible for the 7-O-Glucuronidation of Esculetin and 4-Methylesculetin in Human Liver Microsomes. Drug Metab Dispos. 2015 Jul; 43(7):977-83.
Score: 0.012