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Connection

Ming Hu to Glucuronosyltransferase

This is a "connection" page, showing publications Ming Hu has written about Glucuronosyltransferase.
Connection Strength

4.189
  1. Inhibition of Human UGT1A1-Mediated Bilirubin Glucuronidation by Polyphenolic Acids Impact Safety of Popular Salvianolic Acid A/B-Containing Drugs and Herbal Products. Mol Pharm. 2017 Sep 05; 14(9):2952-2966.
    View in: PubMed
    Score: 0.537
  2. Glucuronidation: driving factors and their impact on glucuronide disposition. Drug Metab Rev. 2017 05; 49(2):105-138.
    View in: PubMed
    Score: 0.534
  3. Establishment and use of new MDCK II cells overexpressing both UGT1A1 and MRP2 to characterize flavonoid metabolism via the glucuronidation pathway. Mol Nutr Food Res. 2016 Sep; 60(9):1967-83.
    View in: PubMed
    Score: 0.503
  4. In?vitro glucuronidation of methyl gallate and pentagalloyl glucopyranose by liver microsomes. Drug Metab Pharmacokinet. 2016 Aug; 31(4):292-303.
    View in: PubMed
    Score: 0.495
  5. Irinotecan decreases intestinal UDP-glucuronosyltransferase (UGT) 1A1 via TLR4/MyD88 pathway prior to the onset of diarrhea. Food Chem Toxicol. 2022 Aug; 166:113246.
    View in: PubMed
    Score: 0.190
  6. UGT1A1 dysfunction increases liver burden and aggravates hepatocyte damage caused by long-term bilirubin metabolism disorder. Biochem Pharmacol. 2021 Aug; 190:114592.
    View in: PubMed
    Score: 0.176
  7. Irinotecan-mediated diarrhea is mainly correlated with intestinal exposure to SN-38: Critical role of gut Ugt. Toxicol Appl Pharmacol. 2020 07 01; 398:115032.
    View in: PubMed
    Score: 0.164
  8. Insight into tartrate inhibition patterns in vitro and in vivo based on cocrystal structure with UDP-glucuronosyltransferase 2B15. Biochem Pharmacol. 2020 Feb; 172:113753.
    View in: PubMed
    Score: 0.160
  9. Potential of herb-drug / herb interactions between substrates and inhibitors of UGTs derived from herbal medicines. Pharmacol Res. 2019 Dec; 150:104510.
    View in: PubMed
    Score: 0.158
  10. Interplay of Efflux Transporters with Glucuronidation and Its Impact on Subcellular Aglycone and Glucuronide Disposition: A Case Study with Kaempferol. Mol Pharm. 2018 Dec 03; 15(12):5602-5614.
    View in: PubMed
    Score: 0.148
  11. Age-related changes in hepatic expression and activity of drug metabolizing enzymes in male wild-type and breast cancer resistance protein knockout mice. Biopharm Drug Dispos. 2018 Jul; 39(7):344-353.
    View in: PubMed
    Score: 0.144
  12. Profiles and Gender-Specifics of UDP-Glucuronosyltransferases and Sulfotransferases Expressions in the Major Metabolic Organs of Wild-Type and Efflux Transporter Knockout FVB Mice. Mol Pharm. 2017 Sep 05; 14(9):2967-2976.
    View in: PubMed
    Score: 0.135
  13. Transport-Glucuronidation Classification System and PBPK Modeling: New Approach To Predict the Impact of Transporters on Disposition of Glucuronides. Mol Pharm. 2017 09 05; 14(9):2884-2898.
    View in: PubMed
    Score: 0.132
  14. Metabolic Disposition of Luteolin Is Mediated by the Interplay of UDP-Glucuronosyltransferases and Catechol-O-Methyltransferases in Rats. Drug Metab Dispos. 2017 03; 45(3):306-315.
    View in: PubMed
    Score: 0.130
  15. Species- and gender-dependent differences in the glucuronidation of a flavonoid glucoside and its aglycone determined using expressed UGT enzymes and microsomes. Biopharm Drug Dispos. 2015 Dec; 36(9):622-35.
    View in: PubMed
    Score: 0.121
  16. Curcumin Affects Phase II Disposition of Resveratrol Through Inhibiting Efflux Transporters MRP2 and BCRP. Pharm Res. 2016 Mar; 33(3):590-602.
    View in: PubMed
    Score: 0.120
  17. UDP-Glucuronosyltransferases 1A6 and 1A9 are the Major Isozymes Responsible for the 7-O-Glucuronidation of Esculetin and 4-Methylesculetin in Human Liver Microsomes. Drug Metab Dispos. 2015 Jul; 43(7):977-83.
    View in: PubMed
    Score: 0.115
  18. A combined strategy of mass fragmentation, post-column cobalt complexation and shift in ultraviolet absorption spectra to determine the uridine 5'-diphospho-glucuronosyltransferase metabolism profiling of flavones after oral administration of a flavone mixture in rats. J Chromatogr A. 2015 May 22; 1395:116-28.
    View in: PubMed
    Score: 0.115
  19. Age-and Region-Dependent Disposition of Raloxifene in Rats. Pharm Res. 2021 Aug; 38(8):1357-1367.
    View in: PubMed
    Score: 0.045
  20. Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Determine the Disposition of Esculetin-7-O-Glucuronide and 4-Methylesculetin-7-O-Glucuronide. Drug Metab Dispos. 2019 03; 47(3):203-214.
    View in: PubMed
    Score: 0.037
  21. High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences. Drug Metab Dispos. 2017 06; 45(6):624-634.
    View in: PubMed
    Score: 0.033
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.