Gregory Cuny to Humans
This is a "connection" page, showing publications Gregory Cuny has written about Humans.
Connection Strength
0.987
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Pyridopyrimidinones as a new chemotype of calcium dependent protein kinase 1 (CDPK1) inhibitors for Cryptosporidium. Mol Biochem Parasitol. 2024 12; 260:111637.
Score: 0.091
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Structure-activity relationship of BMS906024 derivatives for Cryptosporidium parvum growth inhibition. Bioorg Med Chem Lett. 2023 06 15; 90:129328.
Score: 0.084
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Design of pyrido[2,3-d]pyrimidin-7-one inhibitors of receptor interacting protein kinase-2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling. Eur J Med Chem. 2021 Apr 05; 215:113252.
Score: 0.072
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Mycophenolic anilides as broad specificity inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitors. Bioorg Med Chem Lett. 2020 12 15; 30(24):127543.
Score: 0.070
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RIPK protein kinase family: Atypical lives of typical kinases. Semin Cell Dev Biol. 2021 01; 109:96-105.
Score: 0.070
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Receptor-interacting protein kinase 2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling inhibitors based on a 3,5-diphenyl-2-aminopyridine scaffold. Eur J Med Chem. 2020 Aug 15; 200:112417.
Score: 0.069
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Activation loop targeting strategy for design of receptor-interacting protein kinase 2 (RIPK2) inhibitors. Bioorg Med Chem Lett. 2018 02 15; 28(4):577-583.
Score: 0.059
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Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitors: a patent and scientific literature review (2002-2016). Expert Opin Ther Pat. 2017 Jun; 27(6):677-690.
Score: 0.055
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Divergent Approach for the Synthesis of Gombamide A and Derivatives. Org Lett. 2016 09 16; 18(18):4726-9.
Score: 0.053
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Synthesis and Antiproliferative Activity Evaluation of the Disulfide-Containing Cyclic Peptide Thiochondrilline C and Derivatives. J Nat Prod. 2015 Oct 23; 78(10):2398-404.
Score: 0.050
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Discovery of LRRK2 inhibitors using sequential in silico joint pharmacophore space (JPS) and ensemble docking. Bioorg Med Chem Lett. 2015 Jul 01; 25(13):2713-9.
Score: 0.048
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Foreword: neurodegenerative diseases: challenges and opportunities. Future Med Chem. 2012 Sep; 4(13):1647-9.
Score: 0.040
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Necroptosis blockade prevents lung injury in severe influenza. Nature. 2024 Apr; 628(8009):835-843.
Score: 0.022
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A small molecule exerts selective antiviral activity by targeting the human cytomegalovirus nuclear egress complex. PLoS Pathog. 2023 Nov; 19(11):e1011781.
Score: 0.022
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Nonhydrolyzable d-phenylalanine-benzoxazole derivatives retain antitubercular activity. Bioorg Med Chem Lett. 2023 01 15; 80:129116.
Score: 0.021
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Development of Rofecoxib-Based Fluorescent Probes and Investigations on Their Solvatochromism, AIE Activity, Mechanochromism, and COX-2-Targeted Bioimaging. Anal Chem. 2021 09 07; 93(35):11991-12000.
Score: 0.019
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Targeted Degradation of the Oncogenic Phosphatase SHP2. Biochemistry. 2021 08 31; 60(34):2593-2609.
Score: 0.019
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Antioxidant and food additive BHA prevents TNF cytotoxicity by acting as a direct RIPK1 inhibitor. Cell Death Dis. 2021 07 14; 12(7):699.
Score: 0.019
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One-Step Transformation from Rofecoxib to a COX-2 NIR Probe for Human Cancer Tissue/Organoid Targeted Bioimaging. ACS Appl Bio Mater. 2021 03 15; 4(3):2723-2731.
Score: 0.018
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Genetic ablation of purine salvage in Cryptosporidium parvum reveals nucleotide uptake from the host cell. Proc Natl Acad Sci U S A. 2019 10 15; 116(42):21160-21165.
Score: 0.016
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Discovery of 3-(4-sulfamoylnaphthyl)pyrazolo[1,5-a]pyrimidines as potent and selective ALK2 inhibitors. Bioorg Med Chem Lett. 2018 11 01; 28(20):3356-3362.
Score: 0.015
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Small molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling. EMBO J. 2018 09 03; 37(17).
Score: 0.015
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Expanding Benzoxazole-Based Inosine 5'-Monophosphate Dehydrogenase (IMPDH) Inhibitor Structure-Activity As Potential Antituberculosis Agents. J Med Chem. 2018 06 14; 61(11):4739-4756.
Score: 0.015
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Benzoxazoles, Phthalazinones, and Arylurea-Based Compounds with IMP Dehydrogenase-Independent Antibacterial Activity against Francisella tularensis. Antimicrob Agents Chemother. 2017 10; 61(10).
Score: 0.014
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Inflammatory Signaling by NOD-RIPK2 Is Inhibited by Clinically Relevant Type II Kinase Inhibitors. Chem Biol. 2015 Sep 17; 22(9):1174-84.
Score: 0.012