"Wnt Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND FETAL DEVELOPMENT, and tissue maintenance. They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN.
| Descriptor ID |
D051153
|
| MeSH Number(s) |
D12.776.467.984 D23.529.984
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Wnt Proteins".
Below are MeSH descriptors whose meaning is more specific than "Wnt Proteins".
This graph shows the total number of publications written about "Wnt Proteins" by people in this website by year, and whether "Wnt Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Wnt Proteins" by people in Profiles.
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Divergent functions of the evolutionarily conserved, yet seemingly dispensable, Wnt target, sp5. Differentiation. 2025 Jan-Feb; 141:100829.
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Drivers and suppressors of triple-negative breast cancer. Proc Natl Acad Sci U S A. 2021 08 17; 118(33).
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Analysis of the wnt1 regulatory chromosomal landscape. Dev Genes Evol. 2019 05; 229(2-3):43-52.
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Epithelial oestrogen receptor a is dispensable for the development of oestrogen-induced cervical neoplastic diseases. J Pathol. 2018 06; 245(2):147-152.
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PPAR? agonists promote differentiation of cancer stem cells by restraining YAP transcriptional activity. Oncotarget. 2016 Sep 20; 7(38):60954-60970.
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Macrophages engulf endothelial cell membrane particles preceding pupillary membrane capillary regression. Dev Biol. 2015 Jul 01; 403(1):30-42.
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Zygotic expression of Exostosin1 (Ext1) is required for BMP signaling and establishment of dorsal-ventral pattern in Xenopus. Int J Dev Biol. 2014; 58(1):27-34.
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Brief report: Oct4 and canonical Wnt signaling regulate the cardiac lineage factor Mesp1 through a Tcf/Lef-Oct4 composite element. Stem Cells. 2013 Jun; 31(6):1213-7.
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Transient Mesp1 expression: a driver of cardiac cell fate determination. Transcription. 2013; 4(3):92-6.