Ribosome Inactivating Proteins, Type 2
"Ribosome Inactivating Proteins, Type 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Ribosome inactivating proteins consisting of two polypeptide chains, the toxic A subunit and a lectin B subunit, linked by disulfide bridges. The lectin portion binds to cell surfaces and facilitates transport into the ENDOPLASMIC RETICULUM.
Descriptor ID |
D054790
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MeSH Number(s) |
D08.811.277.450.430.700.750 D12.776.765.678.906 D12.776.765.710.750
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Ribosome Inactivating Proteins, Type 2".
Below are MeSH descriptors whose meaning is more specific than "Ribosome Inactivating Proteins, Type 2".
This graph shows the total number of publications written about "Ribosome Inactivating Proteins, Type 2" by people in this website by year, and whether "Ribosome Inactivating Proteins, Type 2" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 1 | 1 |
2005 | 0 | 1 | 1 |
2011 | 1 | 0 | 1 |
2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ribosome Inactivating Proteins, Type 2" by people in Profiles.
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Articulatin-D induces apoptosis via activation of caspase-8 in acute T-cell leukemia cell line. Mol Cell Biochem. 2017 Feb; 426(1-2):87-99.
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A cytotoxic type-2 ribosome inactivating protein (from leafless mistletoe) lacking sugar binding activity. Int J Biol Macromol. 2011 Dec 01; 49(5):1096-103.
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Crystal structure of himalayan mistletoe ribosome-inactivating protein reveals the presence of a natural inhibitor and a new functionally active sugar-binding site. J Biol Chem. 2005 May 27; 280(21):20712-21.
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Structure of a novel ribosome-inactivating protein from a hemi-parasitic plant inhabiting the northwestern Himalayas. Acta Crystallogr D Biol Crystallogr. 2004 Dec; 60(Pt 12 Pt 2):2295-304.