Protein-Arginine N-Methyltransferases
"Protein-Arginine N-Methyltransferases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze the methylation of arginine residues of proteins to yield N-mono- and N,N-dimethylarginine. This enzyme is found in many organs, primarily brain and spleen.
| Descriptor ID |
D011484
|
| MeSH Number(s) |
D08.811.913.555.500.800.750
|
| Concept/Terms |
Protein-Arginine N-Methyltransferases- Protein-Arginine N-Methyltransferases
- N-Methyltransferases, Protein-Arginine
- Protein Arginine N Methyltransferases
- Protein Arginine Methyltransferase
- Arginine Methyltransferase, Protein
- Methyltransferase, Protein Arginine
- Protein Methyltransferase I
- Protein-Arginine N-Methyltransferase
- N-Methyltransferase, Protein-Arginine
- Protein Arginine N Methyltransferase
- Arginine Methylase
- Protein Methylase I
|
Below are MeSH descriptors whose meaning is more general than "Protein-Arginine N-Methyltransferases".
Below are MeSH descriptors whose meaning is more specific than "Protein-Arginine N-Methyltransferases".
This graph shows the total number of publications written about "Protein-Arginine N-Methyltransferases" by people in this website by year, and whether "Protein-Arginine N-Methyltransferases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
| 2023 | 0 | 2 | 2 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Protein-Arginine N-Methyltransferases" by people in Profiles.
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MTA-cooperative PRMT5 inhibitors enhance T cell-mediated antitumor activity in MTAP-loss tumors. J Immunother Cancer. 2024 Sep 23; 12(9).
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PRMT blockade induces defective DNA replication stress response and synergizes with PARP inhibition. Cell Rep Med. 2023 Dec 19; 4(12):101326.
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The cancer testis antigen TDRD1 regulates prostate cancer proliferation by associating with the snRNP biogenesis machinery. Oncogene. 2023 06; 42(22):1821-1831.
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Inhibiting Type I Arginine Methyltransferase Activity Promotes T Cell-Mediated Antitumor Immune Responses. Cancer Immunol Res. 2022 Apr 01; 10(4):420-436.
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Integrating genome-wide CRISPR immune screen with multi-omic clinical data reveals distinct classes of tumor intrinsic immune regulators. J Immunother Cancer. 2021 02; 9(2).