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Navin Varadarajan

TitleProfessor
InstitutionUniversity of Houston
DepartmentBiomedical Engineering
Address4800 Calhoun Rd
Houston TX 77004
Phone713-743-1691
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    Collapse Research 
    Collapse research activities and funding
    R01GM143243     (VARADARAJAN, NAVIN)Sep 25, 2021 - Aug 31, 2025
    NIH
    MusIC: A multi-scale technology for integrating dynamic cellular function and molecular profiles
    Role: Principal Investigator
    U01AI148118     (GEORGIOU, GEORGE GEORGIOU)Dec 19, 2019 - Nov 30, 2024
    NIH
    Systematic, molecular level analysis of the Fc receptor ligation on antibody effector functions
    Role: Co-Principal Investigator
    R01CA174385     (VARADARAJAN, NAVIN)Sep 19, 2012 - Jun 30, 2018
    NIH
    Quantitative single-cell biomarkers of T-cells to optimize tumor immunotherapy
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Yang DS, Tilson A, Sherman MB, Varadarajan N, Vekilov PG. Mesoscopic p53-rich clusters represent a new class of protein condensates. Biophys Rev (Melville). 2025 Mar; 6(1):011308. PMID: 40124402; PMCID: PMC11928095.
      Citations:    
    2. Yankaskas CL, Thompson KN, Paul CD, Vitolo MI, Mistriotis P, Mahendra A, Bajpai VK, Shea DJ, Manto KM, Chai AC, Varadarajan N, Kontrogianni-Konstantopoulos A, Martin SS, Konstantopoulos K. Author Correction: A microfluidic assay for the quantification of the metastatic propensity of breast cancer specimens. Nat Biomed Eng. 2025 Feb; 9(2):285. PMID: 39910377.
      Citations:    Fields:    
    3. Gad AZ, Morris JS, Godret-Miertschin L, Montalvo MJ, Kerr SS, Berger H, Lee JCH, Saadeldin AM, Abu-Arja MH, Xu S, Vasileiou S, Brock RM, Fousek K, Sheha MF, Srinivasan M, Li Y, Saeedi A, R Levental K, Leen AM, Mamonkin M, Carisey A, Varadarajan N, Hegde M, Joseph SK, Levental I, Mukherjee M, Ahmed N. Molecular dynamics at immune synapse lipid rafts influence the cytolytic behavior of CAR T cells. Sci Adv. 2025 Jan 10; 11(2):eadq8114. PMID: 39792660; PMCID: PMC11721525.
      Citations:    Fields:    Translation:HumansCells
    4. Steffin D, Ghatwai N, Montalbano A, Rathi P, Courtney AN, Arnett AB, Fleurence J, Sweidan R, Wang T, Zhang H, Masand P, Maris JM, Martinez D, Pogoriler J, Varadarajan N, Thakkar SG, Lyon D, Lapteva N, Zhuyong M, Patel K, Lopez-Terrada D, Ramos CA, Lulla P, Armaghany T, Grilley BJ, Gottschalk S, Dotti G, Metelitsa LS, Heslop HE, Brenner MK, Sumazin P, Heczey A. Interleukin-15-armoured GPC3 CAR T cells for patients with solid cancers. Nature. 2025 Jan; 637(8047):940-946. PMID: 39604730.
      Citations: 1     Fields:    
    5. Acharya S, Basar R, Daher M, Rafei H, Li P, Uprety N, Ensley E, Shanley M, Kumar B, Banerjee PP, Melo Garcia L, Lin P, Mohanty V, Kim KH, Jiang X, Pan Y, Li Y, Liu B, Nunez Cortes AK, Zhang C, Fathi M, Rezvan A, Montalvo MJ, Cha SL, Reyes-Silva F, Shrestha R, Guo X, Kundu K, Biederst?dt A, Muniz-Feliciano L, Deyter GM, Kaplan M, Jiang XR, Liu E, Jain A, Roszik J, Fowlkes NW, Solis Soto LM, Raso MG, Khoury JD, Lin P, Vega F, Varadarajan N, Chen K, Marin D, Shpall EJ, Rezvani K. CD28 Costimulation Augments CAR Signaling in NK Cells via the LCK/CD3?/ZAP70 Signaling Axis. Cancer Discov. 2024 Oct 04; 14(10):1879-1900. PMID: 38900051; PMCID: PMC11452288.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    6. Wu KL, Montalvo MJ, Menon PS, Roysam B, Varadarajan N. PostFocus: automated selective post-acquisition high-throughput focus restoration using diffusion model for label-free time-lapse microscopy. Bioinformatics. 2024 08 02; 40(8). PMID: 39042160; PMCID: PMC11520405.
      Citations:    Fields:    Translation:Humans
    7. Leekha A, Saeedi A, Sefat KMSR, Kumar M, Martinez-Paniagua M, Damian A, Kulkarni R, Reichel K, Rezvan A, Masoumi S, Liu X, Cooper LJN, Sebastian M, Sands CM, Das VE, Patel NB, Hurst B, Varadarajan N. Multi-antigen intranasal vaccine protects against challenge with sarbecoviruses and prevents transmission in hamsters. Nat Commun. 2024 Jul 23; 15(1):6193. PMID: 39043645; PMCID: PMC11266618.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    8. Leekha A, Saeedi A, Kumar M, Sefat KMSR, Martinez-Paniagua M, Meng H, Fathi M, Kulkarni R, Reichel K, Biswas S, Tsitoura D, Liu X, Cooper LJN, Sands CM, Das VE, Sebastian M, Hurst BL, Varadarajan N. An intranasal nanoparticle STING agonist protects against respiratory viruses in animal models. Nat Commun. 2024 Jul 18; 15(1):6053. PMID: 39025863; PMCID: PMC11258242.
      Citations:    Fields:    Translation:HumansAnimalsCells
    9. Rezvan A, Romain G, Fathi M, Heeke D, Martinez-Paniagua M, An X, Bandey IN, Montalvo MJ, Adolacion JRT, Saeedi A, Sadeghi F, Fousek K, Puebla-Osorio N, Cooper LJN, Bernatchez C, Singh H, Ahmed N, Mattie M, Bot A, Neelapu S, Varadarajan N. Author Correction: Identification of a clinically efficacious CAR T cell subset in diffuse large B cell lymphoma by dynamic multidimensional single-cell profiling. Nat Cancer. 2024 Jun; 5(6):954. PMID: 38778179.
      Citations: 1     Fields:    
    10. Rezvan A, Romain G, Fathi M, Heeke D, Martinez-Paniagua M, An X, Bandey IN, Montalvo MJ, Adolacion JRT, Saeedi A, Sadeghi F, Fousek K, Puebla-Osorio N, Cooper LJN, Bernatchez C, Singh H, Ahmed N, Mattie M, Bot A, Neelapu S, Varadarajan N. Identification of a clinically efficacious CAR T cell subset in diffuse large B cell lymphoma by dynamic multidimensional single-cell profiling. Nat Cancer. 2024 Jul; 5(7):1010-1023. PMID: 38750245.
      Citations: 1     Fields:    Translation:HumansCells
    11. Sefat KMSR, Kumar M, Kehl S, Kulkarni R, Leekha A, Paniagua MM, Ackart DF, Jones N, Spencer C, Podell BK, Ouellet H, Varadarajan N. An intranasal nanoparticle vaccine elicits protective immunity against Mycobacterium tuberculosis. Vaccine. 2024 Sep 17; 42(22):125909. PMID: 38704256.
      Citations: 1     Fields:    Translation:AnimalsCells
    12. Kumar M, Leekha A, Nandy S, Kulkarni R, Martinez-Paniagua M, Rahman Sefat KMS, Willson RC, Varadarajan N. Enzymatic depletion of circulating glutamine is immunosuppressive in cancers. iScience. 2024 Jun 21; 27(6):109817. PMID: 38770139; PMCID: PMC11103382.
      Citations: 1     
    13. Steffin D, Ghatwai N, Montalbano A, Rathi P, Courtney AN, Arnett AB, Fleurence J, Sweidan R, Wang T, Zhang H, Masand P, Maris JM, Martinez D, Pogoriler J, Varadarajan N, Thakkar SG, Lyon D, Lapteva N, Mei Z, Patel K, Lopez-Terrada D, Ramos C, Lulla P, Armaghany T, Grilley BJ, Dotti G, Metelitsa LS, Heslop HE, Brenner MK, Sumazin P, Heczey A. Interleukin-15-armored GPC3-CAR T cells for patients with solid cancers. Res Sq. 2024 Apr 03. PMID: 38645165; PMCID: PMC11030543.
      Citations:    
    14. Kulkarni R, Maranholkar V, Nguyen N, Cirino PC, Willson RC, Varadarajan N. The efficient synthesis and purification of 2'3'- cGAMP from Escherichia coli. Front Microbiol. 2024; 15:1345617. PMID: 38525075; PMCID: PMC10957790.
      Citations:    
    15. Li Y, Basar R, Wang G, Liu E, Moyes JS, Li L, Kerbauy LN, Uprety N, Fathi M, Rezvan A, Banerjee PP, Muniz-Feliciano L, Laskowski TJ, Ensley E, Daher M, Shanley M, Mendt M, Acharya S, Liu B, Biederst?dt A, Rafei H, Guo X, Melo Garcia L, Lin P, Ang S, Marin D, Chen K, Bover L, Champlin RE, Varadarajan N, Shpall EJ, Rezvani K. Author Correction: KIR-based inhibitory CARs overcome CAR-NK cell trogocytosis-mediated fratricide and tumor escape. Nat Med. 2024 Mar; 30(3):906. PMID: 38182787.
      Citations:    Fields:    
    16. Montalvo MJ, Bandey IN, Rezvan A, Wu KL, Saeedi A, Kulkarni R, Li Y, An X, Sefat KMSR, Varadarajan N. Decoding the mechanisms of chimeric antigen receptor (CAR) T cell-mediated killing of tumors: insights from granzyme and Fas inhibition. Cell Death Dis. 2024 02 02; 15(2):109. PMID: 38307835; PMCID: PMC10837176.
      Citations: 5     Fields:    Translation:HumansCells
    17. Wu KL, Martinez-Paniagua M, Reichel K, Menon PS, Deo S, Roysam B, Varadarajan N. Automated detection of apoptotic bodies and cells in label-free time-lapse high-throughput video microscopy using deep convolutional neural networks. Bioinformatics. 2023 10 03; 39(10). PMID: 37773981; PMCID: PMC10563152.
      Citations:    Fields:    Translation:HumansCells
    18. Fathi M, Martinez-Paniagua M, Rezvan A, Montalvo MJ, Mohanty V, Chen K, Mani SA, Varadarajan N. Identifying signatures of EV secretion in metastatic breast cancer through functional single-cell profiling. iScience. 2023 Apr 21; 26(4):106482. PMID: 37091228; PMCID: PMC10119611.
      Citations: 4     
    19. Li Y, Basar R, Wang G, Liu E, Moyes JS, Li L, Kerbauy LN, Uprety N, Fathi M, Rezvan A, Banerjee PP, Muniz-Feliciano L, Laskowski TJ, Ensley E, Daher M, Shanley M, Mendt M, Acharya S, Liu B, Biederst?dt A, Rafei H, Guo X, Melo Garcia L, Lin P, Ang S, Marin D, Chen K, Bover L, Champlin RE, Varadarajan N, Shpall EJ, Rezvani K. KIR-based inhibitory CARs overcome CAR-NK cell trogocytosis-mediated fratricide and tumor escape. Nat Med. 2022 Oct; 28(10):2133-2144. PMID: 36175679; PMCID: PMC9942695.
      Citations: 53     Fields:    Translation:Cells
    20. Romain G, Strati P, Rezvan A, Fathi M, Bandey IN, Adolacion JRT, Heeke D, Liadi I, Marques-Piubelli ML, Solis LM, Mahendra A, Vega F, Cooper LJ, Singh H, Mattie M, Bot A, Neelapu SS, Varadarajan N. Multidimensional single-cell analysis identifies a role for CD2-CD58 interactions in clinical antitumor T cell responses. J Clin Invest. 2022 09 01; 132(17). PMID: 35881486; PMCID: PMC9433104.
      Citations: 18     Fields:    Translation:HumansCells
    21. Fathi M, Charley L, Cooper LJ, Varadarajan N, Meyer DD. Cytotoxic T lymphocytes targeting a conserved SARS-CoV-2 spike epitope are efficient serial killers. Biotechniques. 2022 04; 72(4):113-120. PMID: 35297693; PMCID: PMC8929396.
      Citations: 2     Fields:    Translation:HumansCells
    22. Doshi A, Bandey I, Nevozhay D, Varadarajan N, Cirino PC. Design and characterization of a salicylic acid-inducible gene expression system for Jurkat cells. J Biotechnol. 2022 Feb 20; 346:11-14. PMID: 35051448; PMCID: PMC9618363.
      Citations:    Fields:    Translation:HumansAnimalsCells
    23. Sadeghi F, Kumar M, Bandey IN, Li X, Roysam B, Varadarajan N. Salicylic acid inducible nucleocytoplasmic shuttling of NPR1 fusion proteins in human cells. Biotechnol Bioeng. 2022 01; 119(1):199-210. PMID: 34698368; PMCID: PMC9618364.
      Citations: 1     Fields:    Translation:HumansCells
    24. Fathi M, Joseph R, Adolacion JRT, Martinez-Paniagua M, An X, Gabrusiewicz K, Mani SA, Varadarajan N. Single-Cell Cloning of Breast Cancer Cells Secreting Specific Subsets of Extracellular Vesicles. Cancers (Basel). 2021 Aug 31; 13(17). PMID: 34503207; PMCID: PMC8430892.
      Citations: 9     
    25. An X, Martinez-Paniagua M, Rezvan A, Sefat SR, Fathi M, Singh S, Biswas S, Pourpak M, Yee C, Liu X, Varadarajan N. Single-dose intranasal vaccination elicits systemic and mucosal immunity against SARS-CoV-2. iScience. 2021 Sep 24; 24(9):103037. PMID: 34462731; PMCID: PMC8388188.
      Citations: 49     
    26. Joseph R, Soundararajan R, Vasaikar S, Yang F, Allton KL, Tian L, den Hollander P, Isgandarova S, Haemmerle M, Mino B, Zhou T, Shin C, Martinez-Paniagua M, Sahin AA, Rodriguez-Canales J, Gelovani J, Chang JT, Acharya G, Sood AK, Wistuba II, Gibbons DL, Solis LM, Barton MC, Varadarajan N, Rosen JM, Zhang XH, Mani SA. CD8+ T cells inhibit metastasis and CXCL4 regulates its function. Br J Cancer. 2021 07; 125(2):176-189. PMID: 33795809; PMCID: PMC8292398.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    27. Yang DS, Saeedi A, Davtyan A, Fathi M, Sherman MB, Safari MS, Klindziuk A, Barton MC, Varadarajan N, Kolomeisky AB, Vekilov PG. Mesoscopic protein-rich clusters host the nucleation of mutant p53 amyloid fibrils. Proc Natl Acad Sci U S A. 2021 03 09; 118(10). PMID: 33653952; PMCID: PMC7958401.
      Citations: 21     Fields:    Translation:HumansCells
    28. Bandey IN, Adolacion JRT, Romain G, Paniagua MM, An X, Saeedi A, Liadi I, You Z, Rajanayake RB, Hwu P, Singh H, Cooper LJ, Varadarajan N. Designed improvement to T-cell immunotherapy by multidimensional single cell profiling. J Immunother Cancer. 2021 03; 9(3). PMID: 33722906; PMCID: PMC7970283.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    29. Zheng J, Ru W, Adolacion JR, Spurgat MS, Liu X, Yuan S, Liang RX, Dong J, Potter AS, Potter SS, Chen K, Chen R, Varadarajan N, Tang SJ. Single-cell RNA-seq analysis reveals compartment-specific heterogeneity and plasticity of microglia. iScience. 2021 Mar 19; 24(3):102186. PMID: 33718838; PMCID: PMC7921843.
      Citations: 27     
    30. Daher M, Basar R, Gokdemir E, Baran N, Uprety N, Nunez Cortes AK, Mendt M, Kerbauy LN, Banerjee PP, Shanley M, Imahashi N, Li L, Lim FLWI, Fathi M, Rezvan A, Mohanty V, Shen Y, Shaim H, Lu J, Ozcan G, Ensley E, Kaplan M, Nandivada V, Bdiwi M, Acharya S, Xi Y, Wan X, Mak D, Liu E, Jiang XR, Ang S, Muniz-Feliciano L, Li Y, Wang J, Kordasti S, Petrov N, Varadarajan N, Marin D, Brunetti L, Skinner RJ, Lyu S, Silva L, Turk R, Schubert MS, Rettig GR, McNeill MS, Kurgan G, Behlke MA, Li H, Fowlkes NW, Chen K, Konopleva M, Champlin RE, Shpall EJ, Rezvani K. Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells. Blood. 2021 02 04; 137(5):624-636. PMID: 32902645; PMCID: PMC7869185.
      Citations: 123     Fields:    Translation:HumansAnimalsCells
    31. Hou J, Wang Y, Shi L, Chen Y, Xu C, Saeedi A, Pan K, Bohat R, Egan NA, McKenzie JA, Mbofung RM, Williams LJ, Yang Z, Sun M, Liang X, Rodon Ahnert J, Varadarajan N, Yee C, Chen Y, Hwu P, Peng W. Integrating genome-wide CRISPR immune screen with multi-omic clinical data reveals distinct classes of tumor intrinsic immune regulators. J Immunother Cancer. 2021 02; 9(2). PMID: 33589527; PMCID: PMC7887353.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    32. Doshi A, Sadeghi F, Varadarajan N, Cirino PC. Small-molecule inducible transcriptional control in mammalian cells. Crit Rev Biotechnol. 2020 Dec; 40(8):1131-1150. PMID: 32862714; PMCID: PMC7914288.
      Citations: 7     Fields:    Translation:Animals
    33. Rath JA, Bajwa G, Carreres B, Hoyer E, Gruber I, Mart?nez-Paniagua MA, Yu YR, Nouraee N, Sadeghi F, Wu M, Wang T, Hebeisen M, Rufer N, Varadarajan N, Ho PC, Brenner MK, Gfeller D, Arber C. Single-cell transcriptomics identifies multiple pathways underlying antitumor function of TCR- and CD8a?-engineered human CD4+ T cells. Sci Adv. 2020 07; 6(27):eaaz7809. PMID: 32923584; PMCID: PMC7455496.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    34. Fousek K, Watanabe J, Joseph SK, George A, An X, Byrd TT, Morris JS, Luong A, Mart?nez-Paniagua MA, Sanber K, Navai SA, Gad AZ, Salsman VS, Mathew PR, Kim HN, Wagner DL, Brunetti L, Jang A, Baker ML, Varadarajan N, Hegde M, Kim YM, Heisterkamp N, Abdel-Azim H, Ahmed N. CAR T-cells that target acute B-lineage leukemia irrespective of CD19 expression. Leukemia. 2021 01; 35(1):75-89. PMID: 32205861; PMCID: PMC7519582.
      Citations: 77     Fields:    Translation:HumansAnimalsCells
    35. Ramesh B, Abnouf S, Mali S, Moree WJ, Patil U, Bark SJ, Varadarajan N. Engineered ChymotrypsiN for Mass Spectrometry-Based Detection of Protein Glycosylation. ACS Chem Biol. 2019 12 20; 14(12):2616-2628. PMID: 31710461.
      Citations: 5     Fields:    Translation:HumansCells
    36. Yuan P, Rezvan A, Li X, Varadarajan N, Van Nguyen H. Phasetime: Deep Learning Approach to Detect Nuclei in Time Lapse Phase Images. J Clin Med. 2019 Aug 02; 8(8). PMID: 31382487; PMCID: PMC6723258.
      Citations: 3     
    37. Varadarajan N, Mohan C. Elucidating the molecular circuitry of autoimmunity. Nat Immunol. 2019 07; 20(7):777-778. PMID: 31209402.
      Citations:    Fields:    Translation:HumansAnimalsCells
    38. Soundararajan R, Fradette JJ, Konen JM, Moulder S, Zhang X, Gibbons DL, Varadarajan N, Wistuba II, Tripathy D, Bernatchez C, Byers LA, Chang JT, Contreras A, Lim B, Parra ER, Roarty EB, Wang J, Yang F, Barton M, Rosen JM, Mani SA. Targeting the Interplay between Epithelial-to-Mesenchymal-Transition and the Immune System for Effective Immunotherapy. Cancers (Basel). 2019 May 24; 11(5). PMID: 31137625; PMCID: PMC6562947.
      Citations: 59     
    39. Yankaskas CL, Thompson KN, Paul CD, Vitolo MI, Mistriotis P, Mahendra A, Bajpai VK, Shea DJ, Manto KM, Chai AC, Varadarajan N, Kontrogianni-Konstantopoulos A, Martin SS, Konstantopoulos K. A microfluidic assay for the quantification of the metastatic propensity of breast cancer specimens. Nat Biomed Eng. 2019 06; 3(6):452-465. PMID: 31061459; PMCID: PMC6563615.
      Citations: 59     Fields:    
    40. Mahendra A, Yang X, Abnouf S, Adolacion JRT, Park D, Soomro S, Roszik J, Coarfa C, Romain G, Wanzeck K, Bridges SL, Aggarwal A, Qiu P, Agarwal SK, Mohan C, Varadarajan N. Beyond Autoantibodies: Biologic Roles of Human Autoreactive B Cells in Rheumatoid Arthritis Revealed by RNA-Sequencing. Arthritis Rheumatol. 2019 04; 71(4):529-541. PMID: 30407753; PMCID: PMC6741783.
      Citations: 8     Fields:    Translation:HumansCells
    41. Lu H, Li J, Martinez-Paniagua MA, Bandey IN, Amritkar A, Singh H, Mayerich D, Varadarajan N, Roysam B. TIMING 2.0: high-throughput single-cell profiling of dynamic cell-cell interactions by time-lapse imaging microscopy in nanowell grids. Bioinformatics. 2019 02 15; 35(4):706-708. PMID: 30084956; PMCID: PMC6378937.
      Citations: 8     Fields:    
    42. Liadi I, Singh H, Romain G, Roysam B, Cooper LJ, Varadarajan N. Defining potency of CAR+ T cells: Fast and furious or slow and steady. Oncoimmunology. 2019; 8(10):e1051298. PMID: 31646063; PMCID: PMC6791448.
      Citations: 3     Fields:    
    43. An X, Varadarajan N. Single-cell technologies for profiling T cells to enable monitoring of immunotherapies. Curr Opin Chem Eng. 2018 Mar; 19:142-152. PMID: 31131208; PMCID: PMC6530921.
      Citations: 4     
    44. An X, Sendra VG, Liadi I, Ramesh B, Romain G, Haymaker C, Martinez-Paniagua M, Lu Y, Radvanyi LG, Roysam B, Varadarajan N. Single-cell profiling of dynamic cytokine secretion and the phenotype of immune cells. PLoS One. 2017; 12(8):e0181904. PMID: 28837583; PMCID: PMC5570329.
      Citations: 25     Fields:    Translation:HumansCells
    45. Ritthipichai K, Haymaker CL, Martinez M, Aschenbrenner A, Yi X, Zhang M, Kale C, Vence LM, Roszik J, Hailemichael Y, Overwijk WW, Varadarajan N, Nurieva R, Radvanyi LG, Hwu P, Bernatchez C. Multifaceted Role of BTLA in the Control of CD8+ T-cell Fate after Antigen Encounter. Clin Cancer Res. 2017 Oct 15; 23(20):6151-6164. PMID: 28754817; PMCID: PMC5748156.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    46. Varadarajan N. Unmassked: Single-Cell Profiling of Immune Cell Populations in Tumors. Mol Ther. 2017 08 02; 25(8):1745-1747. PMID: 28684257; PMCID: PMC5542797.
      Citations: 1     Fields:    Translation:Humans
    47. Lee CH, Romain G, Yan W, Watanabe M, Charab W, Todorova B, Lee J, Triplett K, Donkor M, Lungu OI, Lux A, Marshall N, Lindorfer MA, Goff OR, Balbino B, Kang TH, Tanno H, Delidakis G, Alford C, Taylor RP, Nimmerjahn F, Varadarajan N, Bruhns P, Zhang YJ, Georgiou G. IgG Fc domains that bind C1q but not effector Fc? receptors delineate the importance of complement-mediated effector functions. Nat Immunol. 2017 Aug; 18(8):889-898. PMID: 28604720; PMCID: PMC6015732.
      Citations: 74     Fields:    Translation:HumansAnimalsCells
    48. Moogk D, Zhong S, Yu Z, Liadi I, Rittase W, Fang V, Dougherty J, Perez-Garcia A, Osman I, Zhu C, Varadarajan N, Restifo NP, Frey AB, Krogsgaard M. Constitutive Lck Activity Drives Sensitivity Differences between CD8+ Memory T Cell Subsets. J Immunol. 2016 07 15; 197(2):644-54. PMID: 27271569; PMCID: PMC4935560.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    49. Mahendra A, Peyron I, Thaunat O, Dollinger C, Gilardin L, Sharma M, Wootla B, Rao DN, Padiolleau-Lefevre S, Boquet D, More A, Varadarajan N, Kaveri SV, Legendre C, Lacroix-Desmazes S. Generation of Catalytic Antibodies Is an Intrinsic Property of an Individual's Immune System: A Study on a Large Cohort of Renal Transplant Patients. J Immunol. 2016 05 15; 196(10):4075-81. PMID: 27067006; PMCID: PMC4868768.
      Citations: 3     Fields:    Translation:Humans
    50. Ramesh B, Frei CS, Cirino PC, Varadarajan N. Functional enrichment by direct plasmid recovery after fluorescence activated cell sorting. Biotechniques. 2015 Sep; 59(3):157-61. PMID: 26345509; PMCID: PMC5173293.
      Citations: 3     Fields:    Translation:Cells
    51. Merouane A, Rey-Villamizar N, Lu Y, Liadi I, Romain G, Lu J, Singh H, Cooper LJ, Varadarajan N, Roysam B. Automated profiling of individual cell-cell interactions from high-throughput time-lapse imaging microscopy in nanowell grids (TIMING). Bioinformatics. 2015 Oct 01; 31(19):3189-97. PMID: 26059718; PMCID: PMC4693004.
      Citations: 28     Fields:    Translation:HumansCells
    52. Liadi I, Singh H, Romain G, Rey-Villamizar N, Merouane A, Adolacion JR, Kebriaei P, Huls H, Qiu P, Roysam B, Cooper LJ, Varadarajan N. Individual Motile CD4(+) T Cells Can Participate in Efficient Multikilling through Conjugation to Multiple Tumor Cells. Cancer Immunol Res. 2015 May; 3(5):473-82. PMID: 25711538; PMCID: PMC4421910.
      Citations: 63     Fields:    Translation:HumansCells
    53. Romain G, Senyukov V, Rey-Villamizar N, Merouane A, Kelton W, Liadi I, Mahendra A, Charab W, Georgiou G, Roysam B, Lee DA, Varadarajan N. Antibody Fc engineering improves frequency and promotes kinetic boosting of serial killing mediated by NK cells. Blood. 2014 Nov 20; 124(22):3241-9. PMID: 25232058; PMCID: PMC4239333.
      Citations: 52     Fields:    Translation:HumansCells
    54. Ogunniyi AO, Thomas BA, Politano TJ, Varadarajan N, Landais E, Poignard P, Walker BD, Kwon DS, Love JC. Profiling human antibody responses by integrated single-cell analysis. Vaccine. 2014 May 19; 32(24):2866-73. PMID: 24602776; PMCID: PMC4164152.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    55. Sendra VG, Lie A, Romain G, Agarwal SK, Varadarajan N. Detection and isolation of auto-reactive human antibodies from primary B cells. Methods. 2013 Dec 01; 64(2):153-9. PMID: 23811296; PMCID: PMC3836837.
      Citations: 7     Fields:    Translation:HumansCells
    56. Liadi I, Roszik J, Romain G, Cooper LJ, Varadarajan N. Quantitative high-throughput single-cell cytotoxicity assay for T cells. J Vis Exp. 2013 Feb 02; (72):e50058. PMID: 23407457; PMCID: PMC3596999.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    57. Ramesh B, Sendra VG, Cirino PC, Varadarajan N. Single-cell characterization of autotransporter-mediated Escherichia coli surface display of disulfide bond-containing proteins. J Biol Chem. 2012 Nov 09; 287(46):38580-9. PMID: 23019324; PMCID: PMC3493903.
      Citations: 12     Fields:    Translation:AnimalsCells
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