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Nimesh B. Patel

TitleProfessor
InstitutionUniversity of Houston
DepartmentOptometry
Address4800 Calhoun Rd
Houston TX 77004
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    Collapse Research 
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    R01EY033743     (PATEL, NIMESH BHIKHU)Aug 1, 2022 - May 31, 2026
    NIH
    OCTA and Glaucoma Progression in the Non-Human Primate
    Role: Principal Investigator
    R01EY029229     (PATEL, NIMESH BHIKHU)Jan 1, 2019 - Dec 31, 2024
    NIH
    Relating Structure to Function in Optic Neuropathies
    Role: Principal Investigator
    K23EY021761     (PATEL, NIMESH BHIKHU)Sep 1, 2011 - Aug 31, 2017
    NIH
    Retinal Nerve Fiber Layer Area in Aging and Glaucoma
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Brunstetter TJ, Zwart SR, Brandt K, Brown DM, Clemett SJ, Douglas GL, Gibson CR, Laurie SS, Lee AG, Macias BR, Mader TH, Mason SS, Meir JU, Morgan AR, Nelman M, Patel N, Sams C, Suresh R, Tarver W, Tsung A, Van Baalen MG, Smith SM. Severe Spaceflight-Associated Neuro-Ocular Syndrome in an Astronaut With 2 Predisposing Factors. JAMA Ophthalmol. 2024 Sep 01; 142(9):808-817. PMID: 39052244; PMCID: PMC11273286.
      Citations: 1     Fields:    Translation:Humans
    2. She Z, Beach KM, Hung LF, Ostrin LA, Smith EL, Patel NB. Optic Nerve Head Morphology and Macula Ganglion Cell Inner Plexiform Layer Thickness in Axially Anisometropic Rhesus Monkeys. Invest Ophthalmol Vis Sci. 2024 Aug 01; 65(10):44. PMID: 39207298; PMCID: PMC11364186.
      Citations:    Fields:    Translation:AnimalsCells
    3. Lal B, She Z, Beach KM, Hung LF, Patel NB, Smith EL, Ostrin LA. Inner Retinal Microvasculature With Refraction in Juvenile Rhesus Monkeys. Transl Vis Sci Technol. 2024 Aug 01; 13(8):42. PMID: 39186302; PMCID: PMC11361384.
      Citations:    Fields:    Translation:Animals
    4. Leekha A, Saeedi A, Sefat KMSR, Kumar M, Martinez-Paniagua M, Damian A, Kulkarni R, Reichel K, Rezvan A, Masoumi S, Liu X, Cooper LJN, Sebastian M, Sands CM, Das VE, Patel NB, Hurst B, Varadarajan N. Multi-antigen intranasal vaccine protects against challenge with sarbecoviruses and prevents transmission in hamsters. Nat Commun. 2024 Jul 23; 15(1):6193. PMID: 39043645; PMCID: PMC11266618.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    5. Venkata Srinivasan V, Carter-Dawson L, Patel NB. Retinal Ganglion Cell Content Underlying Standard Automated Perimetry Size I to V Visual Sensitivities in the Non-Human Primate Experimental Glaucoma Model. Invest Ophthalmol Vis Sci. 2024 Jul 01; 65(8):22. PMID: 38995114; PMCID: PMC11246096.
      Citations:    Fields:    Translation:AnimalsCells
    6. Ostrin LA, Sah RP, Queener HM, Patel NB, Tran R, Shukla D, Mirhajianmoghadam H. Short-Term Myopic Defocus and Choroidal Thickness in Children and Adults. Invest Ophthalmol Vis Sci. 2024 Apr 01; 65(4):22. PMID: 38597724; PMCID: PMC11008753.
      Citations:    Fields:    Translation:Humans
    7. Pusti D, Patel NB, Ostrin LA, Nti AN, Das S, Yoon G. Peripheral Choroidal Response to Localized Defocus Blur: Influence of Native Peripheral Aberrations. Invest Ophthalmol Vis Sci. 2024 Apr 01; 65(4):14. PMID: 38578621; PMCID: PMC11005066.
      Citations: 1     Fields:    Translation:Humans
    8. Sayah DN, Garg I, Katz R, Zhu Y, Cui Y, Zeng R, Tandias R, Moon JY, Vingopoulos F, Wescott HE, Baldwin G, Wang K, Elze T, Ludwig CA, Vavvas DG, Miller JW, Husain D, Kim LA, Patel NA, Miller JB. Characterizing Macular Neovascularization in Myopic Macular Degeneration and Age-Related Macular Degeneration Using Swept Source OCTA. Clin Ophthalmol. 2023; 17:3855-3866. PMID: 38105914; PMCID: PMC10725687.
      Citations:    
    9. Duffy KR, Bear MF, Patel NB, Das VE, Tychsen L. Human deprivation amblyopia: treatment insights from animal models. Front Neurosci. 2023; 17:1249466. PMID: 37795183; PMCID: PMC10545969.
      Citations: 4     
    10. Ustick JJ, Pardon LP, Chettry P, Patel NB, Cheng H. Effects of head-down tilt on optic nerve sheath diameter in healthy subjects. Ophthalmic Physiol Opt. 2023 Nov; 43(6):1531-1539. PMID: 37401194; PMCID: PMC10592427.
      Citations: 1     Fields:    Translation:Humans
    11. Patel NB, Carter-Dawson L, Frishman LJ. Neuroretinal Rim Response to Transient Intraocular Pressure Challenge Predicts the Extent of Retinal Ganglion Cell Loss in Experimental Glaucoma. Invest Ophthalmol Vis Sci. 2023 05 01; 64(5):30. PMID: 37256608; PMCID: PMC10233313.
      Citations: 2     Fields:    Translation:AnimalsCells
    12. Pardon LP, Greenwald SH, Ferguson CR, Patel NB, Young M, Laurie SS, Macias BR. Identification of Factors Associated With the Development of Optic Disc Edema During Spaceflight. JAMA Ophthalmol. 2022 Dec 01; 140(12):1193-1200. PMID: 36301519; PMCID: PMC9614681.
      Citations: 3     Fields:    Translation:Humans
    13. Srinivasan VV, Das S, Patel N. Widefield OCT Imaging for Quantifying Inner Retinal Thickness in the Nonhuman Primate. Transl Vis Sci Technol. 2022 Aug 01; 11(8):12. PMID: 35972432; PMCID: PMC9396678.
      Citations: 5     Fields:    Translation:AnimalsCells
    14. Kremers J, Aher AJ, Parry NRA, Patel NB, Frishman LJ. Electroretinographic responses to luminance and cone-isolating white noise stimuli in macaques. Front Neurosci. 2022; 16:925405. PMID: 35968368; PMCID: PMC9372266.
      Citations: 4     
    15. Musial G, Adhikari S, Mirhajianmoghadam H, Queener HM, Schill AW, Patel NB, Porter J. Longitudinal In Vivo Changes in Radial Peripapillary Capillaries and Optic Nerve Head Structure in Non-Human Primates With Early Experimental Glaucoma. Invest Ophthalmol Vis Sci. 2022 01 03; 63(1):10. PMID: 34994770; PMCID: PMC8742514.
      Citations: 5     Fields:    Translation:AnimalsCells
    16. Marshall-Goebel K, Macias BR, Kramer LA, Hasan KM, Ferguson C, Patel N, Ploutz-Snyder RJ, Lee SMC, Ebert D, Sargsyan A, Dulchavsky S, Hargens AR, Stenger MB, Laurie S. Association of Structural Changes in the Brain and Retina After Long-Duration Spaceflight. JAMA Ophthalmol. 2021 Jul 01; 139(7):781-784. PMID: 34014272; PMCID: PMC8138750.
      Citations: 5     Fields:    Translation:Humans
    17. Macias BR, Ferguson CR, Patel N, Gibson C, Samuels BC, Laurie SS, Lee SMC, Ploutz-Snyder R, Kramer L, Mader TH, Brunstetter T, Alferova IV, Hargens AR, Ebert DJ, Dulchavsky SA, Stenger MB. Changes in the Optic Nerve Head and Choroid Over 1 Year of Spaceflight. JAMA Ophthalmol. 2021 Jun 01; 139(6):663-667. PMID: 33914020; PMCID: PMC8085766.
      Citations: 9     Fields:    Translation:Humans
    18. Kremers J, Aher AJ, Parry NRA, Patel NB, Frishman LJ. Comparison of macaque and human L- and M-cone driven electroretinograms. Exp Eye Res. 2021 05; 206:108556. PMID: 33794198; PMCID: PMC8111691.
      Citations: 3     Fields:    Translation:AnimalsCells
    19. Courson JA, Landry PT, Do T, Spehlmann E, Lafontant PJ, Patel N, Rumbaut RE, Burns AR. Serial Block-Face Scanning Electron Microscopy (SBF-SEM) of Biological Tissue Samples. J Vis Exp. 2021 03 26; (169). PMID: 33843931; PMCID: PMC8225236.
      Citations: 9     Fields:    Translation:Animals
    20. Antwi-Boasiako K, Carter-Dawson L, Harwerth R, Gondo M, Patel N. The Relationship Between Macula Retinal Ganglion Cell Density and Visual Function in the Nonhuman Primate. Invest Ophthalmol Vis Sci. 2021 01 04; 62(1):5. PMID: 33393971; PMCID: PMC7794274.
      Citations: 11     Fields:    Translation:AnimalsCells
    21. Pardon LP, Cheng H, Chettry P, Patel NB. Optic Nerve Head Morphological Changes Over 12 Hours in Seated and Head-Down Tilt Postures. Invest Ophthalmol Vis Sci. 2020 11 02; 61(13):21. PMID: 33186468; PMCID: PMC7671873.
      Citations: 5     Fields:    Translation:HumansCells
    22. Jnawali A, Lin X, Patel NB, Frishman LJ, Ostrin LA. Retinal ganglion cell ablation in guinea pigs. Exp Eye Res. 2021 01; 202:108339. PMID: 33127343; PMCID: PMC7855240.
      Citations: 3     Fields:    Translation:AnimalsCells
    23. Walker MK, Pardon LP, Redfern R, Patel N. IOP and Optic Nerve Head Morphology during Scleral Lens Wear. Optom Vis Sci. 2020 09; 97(9):661-668. PMID: 32932395; PMCID: PMC7687658.
      Citations: 3     Fields:    Translation:Humans
    24. Musial G, Queener HM, Adhikari S, Mirhajianmoghadam H, Schill AW, Patel NB, Porter J. Automatic Segmentation of Retinal Capillaries in Adaptive Optics Scanning Laser Ophthalmoscope Perfusion Images Using a Convolutional Neural Network. Transl Vis Sci Technol. 2020 07; 9(2):43. PMID: 32855847; PMCID: PMC7424955.
      Citations: 4     Fields:    Translation:Humans
    25. Mirhajianmoghadam H, Jnawali A, Musial G, Queener HM, Patel NB, Ostrin LA, Porter J. In vivo assessment of foveal geometry and cone photoreceptor density and spacing in children. Sci Rep. 2020 06 02; 10(1):8942. PMID: 32487997; PMCID: PMC7265395.
      Citations: 11     Fields:    Translation:HumansCells
    26. Macias BR, Patel NB, Gibson CR, Samuels BC, Laurie SS, Otto C, Ferguson CR, Lee SMC, Ploutz-Snyder R, Kramer LA, Mader TH, Brunstetter T, Stenger MB. Association of Long-Duration Spaceflight With Anterior and Posterior Ocular Structure Changes in Astronauts and Their Recovery. JAMA Ophthalmol. 2020 May 01; 138(5):553-559. PMID: 32239198; PMCID: PMC7118682.
      Citations: 36     Fields:    Translation:Humans
    27. Pardon LP, Harwerth RS, Patel NB. Neuroretinal rim response to transient changes in intraocular pressure in healthy non-human primate eyes. Exp Eye Res. 2020 04; 193:107978. PMID: 32081667; PMCID: PMC7113098.
      Citations: 7     Fields:    Translation:AnimalsCells
    28. Laurie SS, Lee SMC, Macias BR, Patel N, Stern C, Young M, Stenger MB. Optic Disc Edema and Choroidal Engorgement in Astronauts During Spaceflight and Individuals Exposed to Bed Rest. JAMA Ophthalmol. 2020 Feb 01; 138(2):165-172. PMID: 31876939; PMCID: PMC6990717.
      Citations: 34     Fields:    Translation:Humans
    29. Pardon LP, Cheng H, Tang RA, Saenz R, Frishman LJ, Patel NB. Custom Optical Coherence Tomography Parameters for Distinguishing Papilledema from Pseudopapilledema. Optom Vis Sci. 2019 08; 96(8):599-608. PMID: 31318797; PMCID: PMC8081440.
      Citations: 4     Fields:    Translation:HumansCells
    30. Ostrin LA, Jnawali A, Carkeet A, Patel NB. Twenty-four hour ocular and systemic diurnal rhythms in children. Ophthalmic Physiol Opt. 2019 09; 39(5):358-369. PMID: 31332822; PMCID: PMC7092716.
      Citations: 27     Fields:    Translation:Humans
    31. Mader TH, Gibson CR, Miller NR, Subramanian PS, Patel NB, Lee AG. An overview of spaceflight-associated neuro-ocular syndrome (SANS). Neurol India. 2019; 67(Supplement):S206-S211. PMID: 31134911.
      Citations: 19     Fields:    Translation:Humans
    32. Takahata T, Patel NB, Balaram P, Chino YM, Kaas JH. Long-term histological changes in the macaque primary visual cortex and the lateral geniculate nucleus after monocular deprivation produced by early restricted retinal lesions and diffuser induced form deprivation. J Comp Neurol. 2018 12 15; 526(18):2955-2972. PMID: 30004587; PMCID: PMC6283693.
      Citations: 7     Fields:    Translation:Animals
    33. Burfield HJ, Patel NB, Ostrin LA. Ocular Biometric Diurnal Rhythms in Emmetropic and Myopic Adults. Invest Ophthalmol Vis Sci. 2018 10 01; 59(12):5176-5187. PMID: 30372744; PMCID: PMC6203176.
      Citations: 37     Fields:    Translation:Humans
    34. Patel N, McAllister F, Pardon L, Harwerth R. The effects of graded intraocular pressure challenge on the optic nerve head. Exp Eye Res. 2018 04; 169:79-90. PMID: 29409880; PMCID: PMC5878999.
      Citations: 22     Fields:    Translation:AnimalsCells
    35. McAllister F, Harwerth R, Patel N. Assessing the True Intraocular Pressure in the Non-human Primate. Optom Vis Sci. 2018 02; 95(2):113-119. PMID: 29370024; PMCID: PMC5796835.
      Citations: 5     Fields:    Translation:HumansAnimals
    36. Patel N, Pass A, Mason S, Gibson CR, Otto C. Optical Coherence Tomography Analysis of the Optic Nerve Head and Surrounding Structures in Long-Duration International Space Station Astronauts. JAMA Ophthalmol. 2018 Feb 01; 136(2):193-200. PMID: 29327060.
      Citations: 27     Fields:    Translation:HumansCells
    37. Hung LF, Arumugam B, Ostrin L, Patel N, Trier K, Jong M, Smith EL. The Adenosine Receptor Antagonist, 7-Methylxanthine, Alters Emmetropizing Responses in Infant Macaques. Invest Ophthalmol Vis Sci. 2018 01 01; 59(1):472-486. PMID: 29368006; PMCID: PMC5786285.
      Citations: 26     Fields:    Translation:Animals
    38. Mader TH, Gibson CR, Otto CA, Sargsyan AE, Miller NR, Subramanian PS, Hart SF, Lipsky W, Patel NB, Lee AG. Why a One-Way Ticket to Mars May Result in One-Way Directional Glymphatic Flow to the Eye: Response. J Neuroophthalmol. 2017 Dec; 37(4):463-464. PMID: 28991102.
      Citations: 3     Fields:    Translation:Humans
    39. Patel NB, Hung LF, Harwerth RS. Postnatal maturation of the fovea in Macaca mulatta using optical coherence tomography. Exp Eye Res. 2017 11; 164:8-21. PMID: 28778401; PMCID: PMC5628152.
      Citations: 10     Fields:    Translation:Animals
    40. Mader TH, Gibson CR, Otto CA, Sargsyan AE, Miller NR, Subramanian PS, Hart SF, Lipsky W, Patel NB, Lee AG. Persistent Asymmetric Optic Disc Swelling After Long-Duration Space Flight: Implications for Pathogenesis. J Neuroophthalmol. 2017 Jun; 37(2):133-139. PMID: 27930421.
      Citations: 47     Fields:    Translation:Humans
    41. Schiffman JS, Patel NB, Cruz RA, Tang RA. Optical Coherence Tomography for the Radiologist. Neuroimaging Clin N Am. 2015 Aug; 25(3):367-82. PMID: 26208414.
      Citations: 1     Fields:    Translation:Humans
    42. Ivers KM, Sredar N, Patel NB, Rajagopalan L, Queener HM, Twa MD, Harwerth RS, Porter J. In Vivo Changes in Lamina Cribrosa Microarchitecture and Optic Nerve Head Structure in Early Experimental Glaucoma. PLoS One. 2015; 10(7):e0134223. PMID: 26230993; PMCID: PMC4521723.
      Citations: 31     Fields:    Translation:AnimalsCells
    43. Sullivan-Mee M, Patel NB, Pensyl D, Qualls C. Relationship Between Juxtapapillary Choroidal Volume and Beta-Zone Parapapillary Atrophy in Eyes With and Without Primary Open-Angle Glaucoma. Am J Ophthalmol. 2015 Oct; 160(4):637-47.e1. PMID: 26144700; PMCID: PMC4569512.
      Citations: 16     Fields:    Translation:Humans
    44. Mader TH, Gibson CR, Lee AG, Patel NB, Hart SF, Pettit DR. Unilateral loss of spontaneous venous pulsations in an astronaut. J Neuroophthalmol. 2015 Jun; 35(2):226-7. PMID: 25756457.
      Citations: 5     Fields:    Translation:Humans
    45. Patel NB, Sullivan-Mee M, Harwerth RS. The relationship between retinal nerve fiber layer thickness and optic nerve head neuroretinal rim tissue in glaucoma. Invest Ophthalmol Vis Sci. 2014 Sep 23; 55(10):6802-16. PMID: 25249610; PMCID: PMC4214209.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    46. Patel NB, Lim M, Gajjar A, Evans KB, Harwerth RS. Age-associated changes in the retinal nerve fiber layer and optic nerve head. Invest Ophthalmol Vis Sci. 2014 Jul 22; 55(8):5134-43. PMID: 25052998; PMCID: PMC4137486.
      Citations: 44     Fields:    Translation:HumansCells
    47. Luo X, Patel NB, Rajagopalan LP, Harwerth RS, Frishman LJ. Relation between macular retinal ganglion cell/inner plexiform layer thickness and multifocal electroretinogram measures in experimental glaucoma. Invest Ophthalmol Vis Sci. 2014 Jun 26; 55(7):4512-24. PMID: 24970256; PMCID: PMC4106250.
      Citations: 17     Fields:    Translation:AnimalsCells
    48. Redfern RL, Patel N, Hanlon S, Farley W, Gondo M, Pflugfelder SC, McDermott AM. Toll-like receptor expression and activation in mice with experimental dry eye. Invest Ophthalmol Vis Sci. 2013 Feb 28; 54(2):1554-63. PMID: 23372055; PMCID: PMC4604718.
      Citations: 34     Fields:    Translation:HumansAnimals
    49. Patel NB, Garcia B, Harwerth RS. Influence of anterior segment power on the scan path and RNFL thickness using SD-OCT. Invest Ophthalmol Vis Sci. 2012 Aug 24; 53(9):5788-98. PMID: 22836769; PMCID: PMC3428111.
      Citations: 20     Fields:    Translation:HumansCells
    50. Patel NB, Wheat JL, Rodriguez A, Tran V, Harwerth RS. Agreement between retinal nerve fiber layer measures from Spectralis and Cirrus spectral domain OCT. Optom Vis Sci. 2012 May; 89(5):E652-66. PMID: 22105330; PMCID: PMC3299866.
      Citations: 35     Fields:    Translation:HumansCells
    51. Ivers KM, Li C, Patel N, Sredar N, Luo X, Queener H, Harwerth RS, Porter J. Reproducibility of measuring lamina cribrosa pore geometry in human and nonhuman primates with in vivo adaptive optics imaging. Invest Ophthalmol Vis Sci. 2011 Jul 23; 52(8):5473-80. PMID: 21546533; PMCID: PMC3176071.
      Citations: 52     Fields:    Translation:HumansAnimals
    52. Hanlon SD, Patel NB, Burns AR. Assessment of postnatal corneal development in the C57BL/6 mouse using spectral domain optical coherence tomography and microwave-assisted histology. Exp Eye Res. 2011 Oct; 93(4):363-70. PMID: 21689647; PMCID: PMC3206168.
      Citations: 14     Fields:    Translation:Animals
    53. Luo X, Patel NB, Harwerth RS, Frishman LJ. Loss of the low-frequency component of the global-flash multifocal electroretinogram in primate eyes with experimental glaucoma. Invest Ophthalmol Vis Sci. 2011 Jun 01; 52(6):3792-804. PMID: 21421870; PMCID: PMC3109055.
      Citations: 20     Fields:    Translation:AnimalsCells
    54. Patel NB, Luo X, Wheat JL, Harwerth RS. Retinal nerve fiber layer assessment: area versus thickness measurements from elliptical scans centered on the optic nerve. Invest Ophthalmol Vis Sci. 2011 Apr; 52(5):2477-89. PMID: 21220552; PMCID: PMC3088544.
      Citations: 34     Fields:    Translation:AnimalsCells
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