Intracellular Signaling Peptides and Proteins
"Intracellular Signaling Peptides and Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins and peptides that are involved in SIGNAL TRANSDUCTION within the cell. Included here are peptides and proteins that regulate the activity of TRANSCRIPTION FACTORS and cellular processes in response to signals from CELL SURFACE RECEPTORS. Intracellular signaling peptide and proteins may be part of an enzymatic signaling cascade or act through binding to and modifying the action of other signaling factors.
| Descriptor ID |
D047908
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| MeSH Number(s) |
D12.644.360 D12.776.476
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Intracellular Signaling Peptides and Proteins".
Below are MeSH descriptors whose meaning is more specific than "Intracellular Signaling Peptides and Proteins".
This graph shows the total number of publications written about "Intracellular Signaling Peptides and Proteins" by people in this website by year, and whether "Intracellular Signaling Peptides and Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 1 | 1 |
| 2013 | 2 | 0 | 2 |
| 2014 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
| 2021 | 0 | 2 | 2 |
| 2022 | 2 | 0 | 2 |
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Below are the most recent publications written about "Intracellular Signaling Peptides and Proteins" by people in Profiles.
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Inhibiting Type I Arginine Methyltransferase Activity Promotes T Cell-Mediated Antitumor Immune Responses. Cancer Immunol Res. 2022 Apr 01; 10(4):420-436.
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Differential Expression of Presynaptic Munc13-1 and Munc13-2 in Mouse Hippocampus Following Ethanol Drinking. Neuroscience. 2022 04 01; 487:166-183.
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Chlamydomonas LZTFL1 mediates phototaxis via controlling BBSome recruitment to the basal body and its reassembly at the ciliary tip. Proc Natl Acad Sci U S A. 2021 Aug 31; 118(35).
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Antioxidant and food additive BHA prevents TNF cytotoxicity by acting as a direct RIPK1 inhibitor. Cell Death Dis. 2021 07 14; 12(7):699.
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Munc13 proteins control regulated exocytosis in mast cells. J Biol Chem. 2018 01 05; 293(1):345-358.
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Changes in podocyte TRPC channels evoked by plasma and sera from patients with recurrent FSGS and by putative glomerular permeability factors. Biochim Biophys Acta Mol Basis Dis. 2017 09; 1863(9):2342-2354.
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Phosphoproteomic analysis reveals regulatory mechanisms at the kidney filtration barrier. J Am Soc Nephrol. 2014 Jul; 25(7):1509-22.
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NOX2 interacts with podocyte TRPC6 channels and contributes to their activation by diacylglycerol: essential role of podocin in formation of this complex. Am J Physiol Cell Physiol. 2013 Nov 01; 305(9):C960-71.
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Opposing effects of podocin on the gating of podocyte TRPC6 channels evoked by membrane stretch or diacylglycerol. Am J Physiol Cell Physiol. 2013 Aug 01; 305(3):C276-89.
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Sustained activation of N-methyl-D-aspartate receptors in podoctyes leads to oxidative stress, mobilization of transient receptor potential canonical 6 channels, nuclear factor of activated T cells activation, and apoptotic cell death. Mol Pharmacol. 2012 Oct; 82(4):728-37.