"Prions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL.
| Descriptor ID |
D011328
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| MeSH Number(s) |
D12.776.785
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| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Prions".
Below are MeSH descriptors whose meaning is more specific than "Prions".
This graph shows the total number of publications written about "Prions" by people in this website by year, and whether "Prions" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 1 | 0 | 1 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Prions" by people in Profiles.
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No evidence of subclinical infection in sheep surviving oral challenge with prions. J Gen Virol. 2025 Mar; 106(3).
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Impact of APOE genotype on prion-type propagation of tauopathy. Acta Neuropathol Commun. 2022 04 19; 10(1):57.