"Amyloid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A fibrous protein complex that consists of proteins folded into a specific cross beta-pleated sheet structure. This fibrillar structure has been found as an alternative folding pattern for a variety of functional proteins. Deposits of amyloid in the form of AMYLOID PLAQUES are associated with a variety of degenerative diseases. The amyloid structure has also been found in a number of functional proteins that are unrelated to disease.
| Descriptor ID |
D000682
|
| MeSH Number(s) |
D05.500.049 D12.776.049
|
| Concept/Terms |
Amyloid- Amyloid
- Amyloid Substance
- Substance, Amyloid
|
Below are MeSH descriptors whose meaning is more general than "Amyloid".
Below are MeSH descriptors whose meaning is more specific than "Amyloid".
This graph shows the total number of publications written about "Amyloid" by people in this website by year, and whether "Amyloid" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2021 | 2 | 0 | 2 |
| 2022 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Amyloid" by people in Profiles.
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Time-Resolved In Situ AFM Measurement of Growth Rates of A?40 Fibrils. Methods Mol Biol. 2023; 2551:63-77.
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Suppression of amyloid-? fibril growth by drug-engineered polymorph transformation. J Biol Chem. 2022 12; 298(12):102662.
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Frustrated peptide chains at the fibril tip control the kinetics of growth of amyloid-? fibrils. Proc Natl Acad Sci U S A. 2021 09 21; 118(38).
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Mesoscopic protein-rich clusters host the nucleation of mutant p53 amyloid fibrils. Proc Natl Acad Sci U S A. 2021 03 09; 118(10).
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Steady, Symmetric, and Reversible Growth and Dissolution of Individual Amyloid-? Fibrils. ACS Chem Neurosci. 2019 06 19; 10(6):2967-2976.
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Polymorphism of Lysozyme Condensates. J Phys Chem B. 2017 10 05; 121(39):9091-9101.