"Inflammasomes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Multiprotein complexes that mediate the activation of CASPASE-1. Dysregulation of inflammasomes has also been linked to a number of autoinflammatory and autoimmune disorders.
| Descriptor ID |
D058847
|
| MeSH Number(s) |
D05.500.224
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Inflammasomes".
Below are MeSH descriptors whose meaning is more specific than "Inflammasomes".
This graph shows the total number of publications written about "Inflammasomes" by people in this website by year, and whether "Inflammasomes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 1 | 0 | 1 |
| 2016 | 3 | 0 | 3 |
| 2017 | 3 | 1 | 4 |
| 2018 | 3 | 0 | 3 |
| 2019 | 4 | 0 | 4 |
| 2020 | 2 | 0 | 2 |
| 2021 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
| 2023 | 1 | 2 | 3 |
| 2024 | 2 | 1 | 3 |
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Below are the most recent publications written about "Inflammasomes" by people in Profiles.
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Rickettsia disrupts and reduces endothelial tight junction protein zonula occludens-1 in association with inflammasome activation. Infect Immun. 2025 Jan 31; 93(1):e0046824.
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IRE1a silences dsRNA to prevent taxane-induced pyroptosis in triple-negative breast cancer. Cell. 2024 Dec 12; 187(25):7248-7266.e34.
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Novel NLRP3 inflammasome inhibitors INF150 and INF195 attenuate isoproterenol-induced hypertrophy in H9c2 rat cardiac myoblast. Vascul Pharmacol. 2024 Jun; 155:107321.
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Contribution of membrane raft redox signalling to visfatin-induced inflammasome activation and podocyte injury. Aging (Albany NY). 2023 Nov 17; 15(22):12738-12748.
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Discovery of a novel 1,3,4-oxadiazol-2-one-based NLRP3 inhibitor as a pharmacological agent to mitigate cardiac and metabolic complications in an experimental model of diet-induced metaflammation. Eur J Med Chem. 2023 Sep 05; 257:115542.
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Contribution of Hepatic Steatosis-Intensified Extracellular Vesicle Release to Aggravated Inflammatory Endothelial Injury in Liver-Specific Asah1 Gene Knockout Mice. Am J Pathol. 2023 Apr; 193(4):493-508.
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Endothelial Acid Sphingomyelinase Promotes NLRP3 Inflammasome and Neointima Formation During Hypercholesterolemia. J Lipid Res. 2022 Dec; 63(12):100298.
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Hepatic small extracellular vesicles promote microvascular endothelial hyperpermeability during NAFLD via novel-miRNA-7. J Nanobiotechnology. 2021 Nov 27; 19(1):396.
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Vascular Protection by Exercise in Obesity: Inflammasome-associated Mechanisms. Med Sci Sports Exerc. 2020 12; 52(12):2538-2545.
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Simvastatin improves lysosome function via enhancing lysosome biogenesis in endothelial cells. Front Biosci (Landmark Ed). 2020 Jan 01; 25(2):283-298.