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Xiang Li

TitleAssistant Professor
InstitutionUniversity of Houston
DepartmentPharmacological and Pharmaceutical Sciences
Address4800 Calhoun Rd
Houston TX 77004
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Li X, Zhao W, Wang Z, Moura AK, Roudbari K, Zuo R, Hu JZ, Wang YT, Li PL, Zhang Y. Acid Sphingomyelinase Regulates AdipoRon-Induced Differentiation of Arterial Smooth Muscle Cells via TFEB Activation. Int J Mol Sci. 2025 Feb 27; 26(5). PMID: 40076784; PMCID: PMC11899876.
      Citations:    
    2. Wang Z, Li X, Moura AK, Hu JZ, Wang YT, Zhang Y. Lysosome Functions in Atherosclerosis: A Potential Therapeutic Target. Cells. 2025 Jan 24; 14(3). PMID: 39936975; PMCID: PMC11816498.
      Citations:    Fields:    
    3. Zuo R, Wang M, Wang YT, ShenTu Y, Moura AK, Zhou Y, Roudbari K, Hu JZ, Li PL, Hao J, Li X, Zhang Y. Ablation of Hepatic Asah1 Gene Disrupts Hepatic Lipid Homeostasis and Promotes Fibrotic Nonalcoholic Steatohepatitis in Mice. Am J Pathol. 2025 Mar; 195(3):542-560. PMID: 39719015.
      Citations:    Fields:    
    4. Zhang Z, Wang D, Xu R, Li X, Wang Z, Zhang Y. The Physiological Functions and Therapeutic Potential of Hypoxia-Inducible Factor-1a in Vascular Calcification. Biomolecules. 2024 Dec 12; 14(12). PMID: 39766299; PMCID: PMC11674127.
      Citations:    Fields:    Translation:HumansAnimalsCells
    5. Wang YT, Moura AK, Zuo R, Zhou W, Wang Z, Roudbari K, Hu JZ, Li PL, Zhang Y, Li X. Coronary Microvascular Dysfunction Is Associated With Augmented Lysosomal Signaling in Hypercholesterolemic Mice. J Am Heart Assoc. 2024 Dec 03; 13(23):e037460. PMID: 39604023; PMCID: PMC11681558.
      Citations:    Fields:    Translation:AnimalsCells
    6. Manubens-Gil L, Zhou Z, Chen H, Ramanathan A, Liu X, Liu Y, Bria A, Gillette T, Ruan Z, Yang J, Radojevic M, Zhao T, Cheng L, Qu L, Liu S, Bouchard KE, Gu L, Cai W, Ji S, Roysam B, Wang CW, Yu H, Sironi A, Iascone DM, Zhou J, Bas E, Conde-Sousa E, Aguiar P, Li X, Li Y, Nanda S, Wang Y, Muresan L, Fua P, Ye B, He HY, Staiger JF, Peter M, Cox DN, Simonneau M, Oberlaender M, Jefferis G, Ito K, Gonzalez-Bellido P, Kim J, Rubel E, Cline HT, Zeng H, Nern A, Chiang AS, Yao J, Roskams J, Livesey R, Stevens J, Liu T, Dang C, Guo Y, Zhong N, Tourassi G, Hill S, Hawrylycz M, Koch C, Meijering E, Ascoli GA, Peng H. Author Correction: BigNeuron: a resource to benchmark and predict performance of algorithms for automated tracing of neurons in light microscopy datasets. Nat Methods. 2024 Oct; 21(10):1959. PMID: 39090383.
      Citations: 1     Fields:    
    7. Wang YT, Moura AK, Zuo R, Zhou W, Wang Z, Roudbari K, Hu JZ, Li PL, Zhang Y, Li X. Coronary Microvascular Dysfunction is Associated with Augmented Lysosomal Signaling in Hypercholesterolemic Mice. bioRxiv. 2024 Jul 12. PMID: 39026774; PMCID: PMC11257577.
      Citations:    
    8. Manubens-Gil L, Zhou Z, Chen H, Ramanathan A, Liu X, Liu Y, Bria A, Gillette T, Ruan Z, Yang J, Radojevic M, Zhao T, Cheng L, Qu L, Liu S, Bouchard KE, Gu L, Cai W, Ji S, Roysam B, Wang CW, Yu H, Sironi A, Iascone DM, Zhou J, Bas E, Conde-Sousa E, Aguiar P, Li X, Li Y, Nanda S, Wang Y, Muresan L, Fua P, Ye B, He HY, Staiger JF, Peter M, Cox DN, Simonneau M, Oberlaender M, Jefferis G, Ito K, Gonzalez-Bellido P, Kim J, Rubel E, Cline HT, Zeng H, Nern A, Chiang AS, Yao J, Roskams J, Livesey R, Stevens J, Liu T, Dang C, Guo Y, Zhong N, Tourassi G, Hill S, Hawrylycz M, Koch C, Meijering E, Ascoli GA, Peng H. BigNeuron: a resource to benchmark and predict performance of algorithms for automated tracing of neurons in light microscopy datasets. Nat Methods. 2023 Jun; 20(6):824-835. PMID: 37069271.
      Citations: 14     Fields:    Translation:Cells
    9. Yuan X, Bhat OM, Zou Y, Li X, Zhang Y, Li PL. Endothelial Acid Sphingomyelinase Promotes NLRP3 Inflammasome and Neointima Formation During Hypercholesterolemia. J Lipid Res. 2022 Dec; 63(12):100298. PMID: 36252682; PMCID: PMC9672920.
      Citations: 4     Fields:    Translation:AnimalsCells
    10. Chen Y, Li G, Bhat OM, Li X, Zhang Y, Li PL. Impairment of Ceramide-Mediated Endothelial Instant Membrane Resealing During Diabetes Mellitus. Front Physiol. 2022; 13:910339. PMID: 35874544; PMCID: PMC9298829.
      Citations: 3     
    11. Li X, Mobilia M, Rucklidge AM, Zia RKP. How does homophily shape the topology of a dynamic network? Phys Rev E. 2021 Oct; 104(4-1):044311. PMID: 34781443.
      Citations: 2     Fields:    
    12. Li X, Liang M, Jiang S, Cao S, Li S, Gao Y, Liu J, Bai Q, Sui N, Zhu Z. Pomegranate-Like CuO2@SiO2 Nanospheres as H2O2 Self-Supplying and Robust Oxygen Generators for Enhanced Antibacterial Activity. ACS Appl Mater Interfaces. 2021 May 19; 13(19):22169-22181. PMID: 33973462.
      Citations: 7     Fields:    Translation:Cells
    13. Li X, Li S, Bai Q, Sui N, Zhu Z. Gold nanoclusters decorated amine-functionalized graphene oxide nanosheets for capture, oxidative stress, and photothermal destruction of bacteria. Colloids Surf B Biointerfaces. 2020 Dec; 196:111313. PMID: 32798985.
      Citations: 8     Fields:    Translation:Cells
    14. Zhang Y, Wang YT, Koka S, Zhang Y, Hussain T, Li X. Simvastatin improves lysosome function via enhancing lysosome biogenesis in endothelial cells. Front Biosci (Landmark Ed). 2020 Jan 01; 25(2):283-298. PMID: 31585890; PMCID: PMC6812495.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    15. Zhang Y, Chen Y, Zhang Y, Li PL, Li X. Contribution of cathepsin B-dependent Nlrp3 inflammasome activation to nicotine-induced endothelial barrier dysfunction. Eur J Pharmacol. 2019 Dec 15; 865:172795. PMID: 31733211; PMCID: PMC6925381.
      Citations: 25     Fields:    Translation:AnimalsCells
    16. Wang YT, Li X, Chen J, McConnell BK, Chen L, Li PL, Chen Y, Zhang Y. Activation of TFEB ameliorates dedifferentiation of arterial smooth muscle cells and neointima formation in mice with high-fat diet. Cell Death Dis. 2019 09 12; 10(9):676. PMID: 31515484; PMCID: PMC6742653.
      Citations: 10     Fields:    Translation:AnimalsCells
    17. Wang YT, Chen J, Li X, Umetani M, Chen Y, Li PL, Zhang Y. Contribution of transcription factor EB to adipoRon-induced inhibition of arterial smooth muscle cell proliferation and migration. Am J Physiol Cell Physiol. 2019 Nov 01; 317(5):C1034-C1047. PMID: 31483704; PMCID: PMC6879882.
      Citations: 11     Fields:    Translation:AnimalsCells
    18. Zhang P, Guan Y, Chen J, Li X, McConnell BK, Zhou W, Boini KM, Zhang Y. Contribution of p62/SQSTM1 to PDGF-BB-induced myofibroblast-like phenotypic transition in vascular smooth muscle cells lacking Smpd1 gene. Cell Death Dis. 2018 11 19; 9(12):1145. PMID: 30451833; PMCID: PMC6242941.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    19. Guan Y, Li X, Umetani M, Boini KM, Li PL, Zhang Y. Tricyclic antidepressant amitriptyline inhibits autophagic flux and prevents tube formation in vascular endothelial cells. Basic Clin Pharmacol Toxicol. 2019 Apr; 124(4):370-384. PMID: 30311396; PMCID: PMC6226027.
      Citations: 9     Fields:    Translation:AnimalsCells
    20. Becker KA, Li X, Seitz A, Steinmann J, Koch A, Schuchman E, Kamler M, Edwards MJ, Caldwell CC, Gulbins E. Neutrophils Kill Reactive Oxygen Species-Resistant Pseudomonas aeruginosa by Sphingosine. Cell Physiol Biochem. 2017; 43(4):1603-1616. PMID: 29040968.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    21. Wang L, Chen Y, Li X, Zhang Y, Gulbins E, Zhang Y. Enhancement of endothelial permeability by free fatty acid through lysosomal cathepsin B-mediated Nlrp3 inflammasome activation. Oncotarget. 2016 Nov 08; 7(45):73229-73241. PMID: 27689324; PMCID: PMC5341975.
      Citations: 65     Fields:    Translation:AnimalsCells
    22. Chen Y, Wang L, Pitzer AL, Li X, Li PL, Zhang Y. Contribution of redox-dependent activation of endothelial Nlrp3 inflammasomes to hyperglycemia-induced endothelial dysfunction. J Mol Med (Berl). 2016 Dec; 94(12):1335-1347. PMID: 27783111; PMCID: PMC5512566.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    23. Xu M, Zhang Q, Li PL, Nguyen T, Li X, Zhang Y. Regulation of dynein-mediated autophagosomes trafficking by ASM in CASMCs. Front Biosci (Landmark Ed). 2016 Jan 01; 21(4):696-706. PMID: 26709800; PMCID: PMC4703364.
      Citations: 7     Fields:    Translation:AnimalsCells
    24. Chen Y, Pitzer AL, Li X, Li PL, Wang L, Zhang Y. Instigation of endothelial Nlrp3 inflammasome by adipokine visfatin promotes inter-endothelial junction disruption: role of HMGB1. J Cell Mol Med. 2015 Dec; 19(12):2715-27. PMID: 26293846; PMCID: PMC4687695.
      Citations: 63     Fields:    Translation:AnimalsCells
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