"Renin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19.
| Descriptor ID |
D012083
|
| MeSH Number(s) |
D08.811.277.656.074.500.780 D08.811.277.656.300.048.780 D08.811.277.656.837.750
|
| Concept/Terms |
Renin- Renin
- Angiotensin-Forming Enzyme
- Angiotensin Forming Enzyme
- Angiotensinogenase
Prorenin- Prorenin
- Inactive Renin
- Renin, Inactive
- Big Renin
- Renin, Big
- Cryorenin
|
Below are MeSH descriptors whose meaning is more general than "Renin".
Below are MeSH descriptors whose meaning is more specific than "Renin".
This graph shows the total number of publications written about "Renin" by people in this website by year, and whether "Renin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Renin" by people in Profiles.
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Angiotensin type 2 receptor null mice express reduced levels of renal angiotensin II type 2 receptor/angiotensin (1-7)/Mas receptor and exhibit greater high-fat diet-induced kidney injury. J Renin Angiotensin Aldosterone Syst. 2016 Jul; 17(3).
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Angiotensin AT2 receptor agonist prevents salt-sensitive hypertension in obese Zucker rats. Am J Physiol Renal Physiol. 2015 Jun 15; 308(12):F1379-85.
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Chronic AT2 receptor activation increases renal ACE2 activity, attenuates AT1 receptor function and blood pressure in obese Zucker rats. Kidney Int. 2013 Nov; 84(5):931-9.
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Protective role of angiotensin II subtype 2 receptor in blood pressure increase in obese Zucker rats. Hypertension. 2009 Feb; 53(2):256-61.