"Synapses" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.
Descriptor ID |
D013569
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MeSH Number(s) |
A08.850 A11.284.149.165.420.780
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Synapses".
Below are MeSH descriptors whose meaning is more specific than "Synapses".
This graph shows the total number of publications written about "Synapses" by people in this website by year, and whether "Synapses" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 3 | 3 |
2009 | 1 | 0 | 1 |
2016 | 1 | 0 | 1 |
2018 | 1 | 0 | 1 |
2019 | 0 | 1 | 1 |
2021 | 1 | 1 | 2 |
2022 | 0 | 1 | 1 |
2023 | 0 | 1 | 1 |
2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Synapses" by people in Profiles.
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Incorporating slow NMDA-type receptors with nonlinear voltage-dependent magnesium block in a next generation neural mass model: derivation and dynamics. J Comput Neurosci. 2024 Aug; 52(3):207-222.
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Injury to Cone Synapses by Retinal Detachment: Differences from Rod Synapses and Protection by ROCK Inhibition. Cells. 2023 05 27; 12(11).
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The quest for multiscale brain modeling. Trends Neurosci. 2022 10; 45(10):777-790.
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Mutants of the white ABCG Transporter in Drosophila melanogaster Have Deficient Olfactory Learning and Cholesterol Homeostasis. Int J Mol Sci. 2021 Nov 30; 22(23).
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ROCK inhibition reduces morphological and functional damage to rod synapses after retinal injury. Sci Rep. 2021 01 12; 11(1):692.
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SNARE Complex-Associated Proteins and Alcohol. Alcohol Clin Exp Res. 2020 01; 44(1):7-18.
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Ethanol Regulates Presynaptic Activity and Sedation through Presynaptic Unc13 Proteins in Drosophila. eNeuro. 2018 May-Jun; 5(3).
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Presynaptic DLG regulates synaptic function through the localization of voltage-activated Ca(2+) Channels. Sci Rep. 2016 Aug 30; 6:32132.
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LTD and LTP at the developing retinogeniculate synapse. J Neurophysiol. 2009 Dec; 102(6):3082-90.
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Differential distribution of vesicle associated membrane protein isoforms in the mouse retina. Mol Vis. 2003 Dec 11; 9:673-88.