"Peripherins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Type III intermediate filament proteins expressed mainly in neurons of the peripheral and CENTRAL NERVOUS SYSTEMS. Peripherins are implicated in neurite elongation during development and axonal regeneration after injury.
| Descriptor ID |
D064531
|
| MeSH Number(s) |
D05.750.078.593.765
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Peripherins".
Below are MeSH descriptors whose meaning is more specific than "Peripherins".
This graph shows the total number of publications written about "Peripherins" by people in this website by year, and whether "Peripherins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 3 | 0 | 3 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 3 | 0 | 3 |
| 2020 | 4 | 0 | 4 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
| 2023 | 0 | 2 | 2 |
| 2024 | 1 | 0 | 1 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Peripherins" by people in Profiles.
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The PRPH2 D2 Loop: Biochemical Insights and Implications in Disease. Adv Exp Med Biol. 2025; 1468:313-317.
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Downregulation of rhodopsin is an effective therapeutic strategy in ameliorating peripherin-2-associated inherited retinal disorders. Nat Commun. 2024 Jun 04; 15(1):4756.
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ROM1 is redundant to PRPH2 as a molecular building block of photoreceptor disc rims. Elife. 2023 Nov 22; 12.
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The Role of Peripherin-2/ROM1 Complexes in Photoreceptor Outer Segment Disc Morphogenesis. Adv Exp Med Biol. 2023; 1415:277-281.
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Prph2 disease mutations lead to structural and functional defects in the RPE. FASEB J. 2022 05; 36(5):e22284.
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Photoreceptor Disc Enclosure Is Tightly Controlled by Peripherin-2 Oligomerization. J Neurosci. 2021 04 21; 41(16):3588-3596.
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Retbindin: A riboflavin Binding Protein, Is Critical for Photoreceptor Homeostasis and Survival in Models of Retinal Degeneration. Int J Mol Sci. 2020 Oct 29; 21(21).
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ROM1 contributes to phenotypic heterogeneity in PRPH2-associated retinal disease. Hum Mol Genet. 2020 09 29; 29(16):2708-2722.
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Syntaxin 3 is essential for photoreceptor outer segment protein trafficking and survival. Proc Natl Acad Sci U S A. 2020 08 25; 117(34):20615-20624.
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The Interplay between Peripherin 2 Complex Formation and Degenerative Retinal Diseases. Cells. 2020 03 24; 9(3).