Intercellular Adhesion Molecule-1
"Intercellular Adhesion Molecule-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cell-surface ligand involved in leukocyte adhesion and inflammation. Its production is induced by gamma-interferon and it is required for neutrophil migration into inflamed tissue.
| Descriptor ID |
D018799
|
| MeSH Number(s) |
D12.776.395.550.200.450 D12.776.543.550.200.450 D23.050.301.350.450
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Intercellular Adhesion Molecule-1".
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This graph shows the total number of publications written about "Intercellular Adhesion Molecule-1" by people in this website by year, and whether "Intercellular Adhesion Molecule-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2010 | 2 | 0 | 2 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Intercellular Adhesion Molecule-1" by people in Profiles.
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Ligand- and cation-induced structural alterations of the leukocyte integrin LFA-1. J Biol Chem. 2018 04 27; 293(17):6565-6577.
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2E8 binds to the high affinity I-domain in a metal ion-dependent manner: a second generation monoclonal antibody selectively targeting activated LFA-1. J Biol Chem. 2010 Oct 22; 285(43):32860-32868.
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ICAM-1 mediates surface contact between neutrophils and keratocytes following corneal epithelial abrasion in the mouse. Exp Eye Res. 2010 Nov; 91(5):676-84.
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A mechanism for antibody-mediated outside-in activation of LFA-1. J Biol Chem. 2008 Apr 18; 283(16):10642-8.