Transcription Factor AP-1
"Transcription Factor AP-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multiprotein complex composed of the products of c-jun and c-fos proto-oncogenes. These proteins must dimerize in order to bind to the AP-1 recognition site, also known as the TPA-responsive element (TRE). AP-1 controls both basal and inducible transcription of several genes.
| Descriptor ID |
D018808
|
| MeSH Number(s) |
D12.776.260.108.875 D12.776.930.127.875
|
| Concept/Terms |
Transcription Factor AP-1- Transcription Factor AP-1
- Transcription Factor AP 1
- AP-1 Enhancer-Binding Protein
- Enhancer-Binding Protein, AP-1
- AP-1
- Activator Protein-1
- Activator Protein 1
- AP-1 Enhancer Binding Protein
- AP 1 Enhancer Binding Protein
|
Below are MeSH descriptors whose meaning is more general than "Transcription Factor AP-1".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factor AP-1".
This graph shows the total number of publications written about "Transcription Factor AP-1" by people in this website by year, and whether "Transcription Factor AP-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transcription Factor AP-1" by people in Profiles.
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Structural and cellular mechanisms of peptidyl-prolyl isomerase Pin1-mediated enhancement of Tissue Factor gene expression, protein half-life, and pro-coagulant activity. Haematologica. 2018 06; 103(6):1073-1082.
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Blockade of AP-1 Potentiates Endocrine Therapy and Overcomes Resistance. Mol Cancer Res. 2016 05; 14(5):470-81.
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Estrogen receptor ? exon 3-deleted mouse: The importance of non-ERE pathways in ER? signaling. Proc Natl Acad Sci U S A. 2015 Apr 21; 112(16):5135-40.