"Caspase 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A long pro-domain caspase that has specificity for the precursor form of INTERLEUKIN-1BETA. It plays a role in INFLAMMATION by catalytically converting the inactive forms of CYTOKINES such as interleukin-1beta to their active, secreted form. Caspase 1 is referred as interleukin-1beta converting enzyme and is frequently abbreviated ICE.
| Descriptor ID |
D020170
|
| MeSH Number(s) |
D08.811.277.656.262.500.126.550.100 D08.811.277.656.300.200.126.550.100 D12.644.360.075.405.550.100 D12.776.476.075.405.550.100
|
| Concept/Terms |
Caspase 1- Caspase 1
- Interleukin-1beta Converting Enzyme
- Converting Enzyme, Interleukin-1beta
- Interleukin 1beta Converting Enzyme
- ICE Protease
- IL1BC Enzyme
- IL-1 beta Convertase
- Convertase, IL-1 beta
- IL 1 beta Convertase
- beta Convertase, IL-1
- CASP1 Caspase
- Caspase, CASP1
- Interleukin-1 Converting Enzyme
- Converting Enzyme, Interleukin-1
- Interleukin 1 Converting Enzyme
- IL-1 beta-Converting Enzyme
- IL 1 beta Converting Enzyme
- beta-Converting Enzyme, IL-1
Procaspase-1- Procaspase-1
- Procaspase 1
- Pro-Caspase-1
- Pro Caspase 1
|
Below are MeSH descriptors whose meaning is more general than "Caspase 1".
Below are MeSH descriptors whose meaning is more specific than "Caspase 1".
This graph shows the total number of publications written about "Caspase 1" by people in this website by year, and whether "Caspase 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 2 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Caspase 1" by people in Profiles.
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Rickettsia disrupts and reduces endothelial tight junction protein zonula occludens-1 in association with inflammasome activation. Infect Immun. 2025 Jan 31; 93(1):e0046824.
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Contribution of membrane raft redox signalling to visfatin-induced inflammasome activation and podocyte injury. Aging (Albany NY). 2023 Nov 17; 15(22):12738-12748.
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Vascular Protection by Exercise in Obesity: Inflammasome-associated Mechanisms. Med Sci Sports Exerc. 2020 12; 52(12):2538-2545.
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Nicotine instigates podocyte injury via NLRP3 inflammasomes activation. Aging (Albany NY). 2019 Dec 13; 11(24):12810-12821.
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Trimethylamine-N-Oxide Instigates NLRP3 Inflammasome Activation and Endothelial Dysfunction. Cell Physiol Biochem. 2017; 44(1):152-162.
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Endothelial NLRP3 inflammasome activation and arterial neointima formation associated with acid sphingomyelinase during hypercholesterolemia. Redox Biol. 2017 Oct; 13:336-344.
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Enhancement of endothelial permeability by free fatty acid through lysosomal cathepsin B-mediated Nlrp3 inflammasome activation. Oncotarget. 2016 Nov 08; 7(45):73229-73241.