Hypoxia-Inducible Factor 1, alpha Subunit
"Hypoxia-Inducible Factor 1, alpha Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Hypoxia-inducible factor 1, alpha subunit is a basic helix-loop-helix transcription factor that is regulated by OXYGEN availability and is targeted for degradation by VHL TUMOR SUPPRESSOR PROTEIN.
Descriptor ID |
D051795
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MeSH Number(s) |
D12.776.260.103.625.750 D12.776.930.125.625.750
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hypoxia-Inducible Factor 1, alpha Subunit".
Below are MeSH descriptors whose meaning is more specific than "Hypoxia-Inducible Factor 1, alpha Subunit".
This graph shows the total number of publications written about "Hypoxia-Inducible Factor 1, alpha Subunit" by people in this website by year, and whether "Hypoxia-Inducible Factor 1, alpha Subunit" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2010 | 0 | 1 | 1 |
2016 | 0 | 1 | 1 |
2017 | 1 | 0 | 1 |
2021 | 0 | 1 | 1 |
2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hypoxia-Inducible Factor 1, alpha Subunit" by people in Profiles.
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The Physiological Functions and Therapeutic Potential of Hypoxia-Inducible Factor-1a in Vascular Calcification. Biomolecules. 2024 Dec 12; 14(12).
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Targeting HIF-activated collagen prolyl 4-hydroxylase expression disrupts collagen deposition and blocks primary and metastatic uveal melanoma growth. Oncogene. 2021 Aug; 40(33):5182-5191.
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Hypoxia inducible factor-1a mediates the profibrotic effect of albumin in renal tubular cells. Sci Rep. 2017 Nov 20; 7(1):15878.
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24-Hydroxycholesterol participates in pancreatic neuroendocrine tumor development. Proc Natl Acad Sci U S A. 2016 10 11; 113(41):E6219-E6227.
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Identifying signatures of natural selection in Tibetan and Andean populations using dense genome scan data. PLoS Genet. 2010 Sep 09; 6(9):e1001116.