G-Protein-Coupled Receptor Kinase 3
"G-Protein-Coupled Receptor Kinase 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously expressed G-protein-coupled receptor kinase subtype that has specificity for the agonist-occupied form of BETA-ADRENERGIC RECEPTORS and a variety of other G-PROTEIN-COUPLED RECEPTORS. Although it is highly homologous to G-PROTEIN-COUPLED RECEPTOR KINASE 2, it is not considered to play an essential role in regulating myocardial contractile response.
Descriptor ID |
D054770
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MeSH Number(s) |
D08.811.913.696.620.682.700.364.049.300 D12.644.360.293.249.300 D12.776.476.293.249.300
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "G-Protein-Coupled Receptor Kinase 3".
Below are MeSH descriptors whose meaning is more specific than "G-Protein-Coupled Receptor Kinase 3".
This graph shows the total number of publications written about "G-Protein-Coupled Receptor Kinase 3" by people in this website by year, and whether "G-Protein-Coupled Receptor Kinase 3" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2006 | 0 | 2 | 2 |
2007 | 0 | 2 | 2 |
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Below are the most recent publications written about "G-Protein-Coupled Receptor Kinase 3" by people in Profiles.
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Activation of the CRF(1) receptor causes ERK1/2 mediated increase in GRK3 expression in CATH.a cells. FEBS Lett. 2007 Jul 10; 581(17):3204-10.
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Extracellular signal-regulated kinase 1/2-mediated transcriptional regulation of G-protein-coupled receptor kinase 3 expression in neuronal cells. J Pharmacol Exp Ther. 2007 Apr; 321(1):51-9.
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Role of 90-kDa heat shock protein (Hsp 90) and protein degradation in regulating neuronal levels of G protein-coupled receptor kinase 3. J Pharmacol Exp Ther. 2007 Mar; 320(3):1106-12.
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Involvement of G protein-coupled receptor kinase (GRK) 3 and GRK2 in down-regulation of the alpha2B-adrenoceptor. J Pharmacol Exp Ther. 2006 Jun; 317(3):1027-35.