G-Protein-Coupled Receptor Kinase 2
"G-Protein-Coupled Receptor Kinase 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously expressed G-protein-coupled receptor kinase subtype that has specificity for the agonist-occupied form of BETA-ADRENERGIC RECEPTORS. It may play an essential role in regulating myocardial contractile response.
| Descriptor ID |
D054769
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| MeSH Number(s) |
D08.811.913.696.620.682.700.364.049.200 D12.644.360.293.249.200 D12.776.476.293.249.200
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "G-Protein-Coupled Receptor Kinase 2".
Below are MeSH descriptors whose meaning is more specific than "G-Protein-Coupled Receptor Kinase 2".
This graph shows the total number of publications written about "G-Protein-Coupled Receptor Kinase 2" by people in this website by year, and whether "G-Protein-Coupled Receptor Kinase 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 2 | 2 |
| 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "G-Protein-Coupled Receptor Kinase 2" by people in Profiles.
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GRK2 negatively regulates glycogen synthesis in mouse liver FL83B cells. J Biol Chem. 2007 Jul 13; 282(28):20612-20.
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Involvement of G protein-coupled receptor kinase (GRK) 3 and GRK2 in down-regulation of the alpha2B-adrenoceptor. J Pharmacol Exp Ther. 2006 Jun; 317(3):1027-35.
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Tempol reduces oxidative stress and restores renal dopamine D1-like receptor- G protein coupling and function in hyperglycemic rats. Am J Physiol Renal Physiol. 2006 Jul; 291(1):F58-66.