"Small Molecule Libraries" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Large collections of small molecules (molecular weight about 600 or less), of similar or diverse nature which are used for high-throughput screening analysis of the gene function, protein interaction, cellular processing, biochemical pathways, or other chemical interactions.
| Descriptor ID |
D054852
|
| MeSH Number(s) |
D27.720.470.765
|
| Concept/Terms |
Small Molecule Libraries- Small Molecule Libraries
- Libraries, Small Molecule
- Molecule Libraries, Small
- Molecular Libraries, Small
- Libraries, Small Molecular
- Small Molecular Libraries
- Chemical Libraries
- Libraries, Chemical
|
Below are MeSH descriptors whose meaning is more general than "Small Molecule Libraries".
Below are MeSH descriptors whose meaning is more specific than "Small Molecule Libraries".
This graph shows the total number of publications written about "Small Molecule Libraries" by people in this website by year, and whether "Small Molecule Libraries" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Small Molecule Libraries" by people in Profiles.
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Intestinal Excretion, Intestinal Recirculation, and Renal Tubule Reabsorption Are Underappreciated Mechanisms That Drive the Distribution and Pharmacokinetic Behavior of Small Molecule Drugs. J Med Chem. 2021 Jun 10; 64(11):7045-7059.
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Identification of Inhibitors of Integrin Cytoplasmic Domain Interactions With Syk. Front Immunol. 2020; 11:575085.
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Covalent-Fragment Screening of BRD4 Identifies a Ligandable Site Orthogonal to the Acetyl-Lysine Binding Sites. ACS Chem Biol. 2020 04 17; 15(4):1036-1049.
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Identification of side arm-modified DOTA scaffolds as multi-site binding ligands for cancer cells over normal cells. Bioorg Med Chem Lett. 2019 Oct 01; 29(19):126619.
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?Np63/DGCR8-Dependent MicroRNAs Mediate Therapeutic Efficacy of HDAC Inhibitors in Cancer. Cancer Cell. 2016 06 13; 29(6):874-888.
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Synthesis of a 2(1H)-pyridone library via rhodium-catalyzed formation of isomunchones. ACS Comb Sci. 2013 Jul 08; 15(7):340-3.
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Design, synthesis, and diversification of 5,5-dimethyl cyclohexen-1,4-dione library. J Comb Chem. 2010 May 10; 12(3):318-20.