"Cell Cycle Checkpoints" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Regulatory signaling systems that control the progression through the CELL CYCLE. They ensure that the cell has completed, in the correct order and without mistakes, all the processes required to replicate the GENOME and CYTOPLASM, and divide them equally between two daughter cells. If cells sense they have not completed these processes or that the environment does not have the nutrients and growth hormones in place to proceed, then the cells are restrained (or "arrested") until the processes are completed and growth conditions are suitable.
Descriptor ID |
D059447
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MeSH Number(s) |
G04.144.109
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Concept/Terms |
Cell Cycle Checkpoints- Cell Cycle Checkpoints
- Cell Cycle Checkpoint
- Checkpoint, Cell Cycle
- Checkpoints, Cell Cycle
Cell Cycle Transition Points- Cell Cycle Transition Points
- Cell Cycle-Transition Points
- Cell Cycle-Transition Point
- Cycle-Transition Point, Cell
- Point, Cell Cycle-Transition
Cell Cycle Arrest- Cell Cycle Arrest
- Arrest, Cell Cycle
- Arrests, Cell Cycle
- Cell Cycle Arrests
Cell Cycle Control- Cell Cycle Control
- Cell Cycle Controls
- Control, Cell Cycle
- Controls, Cell Cycle
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Below are MeSH descriptors whose meaning is more general than "Cell Cycle Checkpoints".
Below are MeSH descriptors whose meaning is more specific than "Cell Cycle Checkpoints".
This graph shows the total number of publications written about "Cell Cycle Checkpoints" by people in this website by year, and whether "Cell Cycle Checkpoints" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2016 | 0 | 2 | 2 |
2017 | 1 | 0 | 1 |
2018 | 1 | 0 | 1 |
2020 | 0 | 1 | 1 |
2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cell Cycle Checkpoints" by people in Profiles.
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A novel role of ADGRF1 (GPR110) in promoting cellular quiescence and chemoresistance in human epidermal growth factor receptor 2-positive breast cancer. FASEB J. 2021 07; 35(7):e21719.
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Chemopreventive Agent 3,3'-Diindolylmethane Inhibits MDM2 in Colorectal Cancer Cells. Int J Mol Sci. 2020 Jun 30; 21(13).
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Viscum articulatum Burm. f. aqueous extract exerts antiproliferative effect and induces cell cycle arrest and apoptosis in leukemia cells. J Ethnopharmacol. 2018 Jun 12; 219:91-102.
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p53 is required for female germline stem cell maintenance in P-element hybrid dysgenesis. Dev Biol. 2018 02 15; 434(2):215-220.
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Novel histone deacetylase inhibitors derived from Magnolia officinalis significantly enhance TRAIL-induced apoptosis in non-small cell lung cancer. Pharmacol Res. 2016 Sep; 111:113-125.
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Artemisinin and its derivatives can significantly inhibit lung tumorigenesis and tumor metastasis through Wnt/ß-catenin signaling. Oncotarget. 2016 May 24; 7(21):31413-28.