"DNA Repair" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The reconstruction of a continuous two-stranded DNA molecule without mismatch from a molecule which contained damaged regions. The major repair mechanisms are excision repair, in which defective regions in one strand are excised and resynthesized using the complementary base pairing information in the intact strand; photoreactivation repair, in which the lethal and mutagenic effects of ultraviolet light are eliminated; and post-replication repair, in which the primary lesions are not repaired, but the gaps in one daughter duplex are filled in by incorporation of portions of the other (undamaged) daughter duplex. Excision repair and post-replication repair are sometimes referred to as "dark repair" because they do not require light.
Descriptor ID |
D004260
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MeSH Number(s) |
G02.111.222 G05.219
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Concept/Terms |
Base Excision Repair- Base Excision Repair
- Base Excision Repairs
- Excision Repair, Base
- Repair, Base Excision
- Repairs, Base Excision
|
Below are MeSH descriptors whose meaning is more general than "DNA Repair".
Below are MeSH descriptors whose meaning is more specific than "DNA Repair".
This graph shows the total number of publications written about "DNA Repair" by people in this website by year, and whether "DNA Repair" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2016 | 0 | 3 | 3 |
2022 | 0 | 1 | 1 |
2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA Repair" by people in Profiles.
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Exploring the links between SOS response, mutagenesis, and resistance during the recovery period. Antimicrob Agents Chemother. 2024 05 02; 68(5):e0146223.
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Genetic variation in P-element dysgenic sterility is associated with double-strand break repair and alternative splicing of TE transcripts. PLoS Genet. 2022 12; 18(12):e1010080.
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SUMOylation of HP1a supports association with ncRNA to define responsiveness of breast cancer cells to chemotherapy. Oncotarget. 2016 May 24; 7(21):30336-49.
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SUMOylated ORC2 Recruits a Histone Demethylase to Regulate Centromeric Histone Modification and Genomic Stability. Cell Rep. 2016 Apr 05; 15(1):147-157.
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Cardiomyocyte-specific conditional knockout of the histone chaperone HIRA in mice results in hypertrophy, sarcolemmal damage and focal replacement fibrosis. Dis Model Mech. 2016 Mar; 9(3):335-45.