"Gene Knock-In Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Techniques used to add in exogenous gene sequence such as mutated genes; REPORTER GENES, to study mechanisms of gene expression; or regulatory control sequences, to study effects of temporal changes to GENE EXPRESSION.
| Descriptor ID |
D055879
|
| MeSH Number(s) |
E05.393.335.249
|
| Concept/Terms |
Gene Knock-In Techniques- Gene Knock-In Techniques
- Gene Knock-In Technique
- Knock-In Technique, Gene
- Knock-In Techniques, Gene
- Technique, Gene Knock-In
- Techniques, Gene Knock-In
- Gene Knock-In
- Gene Knock-Ins
- Knock-In, Gene
- Knock-Ins, Gene
- Gene Knock In
- Gene Knock Ins
- In, Gene Knock
- Ins, Gene Knock
- Knock In, Gene
- Knock Ins, Gene
- Gene Knock In Techniques
|
Below are MeSH descriptors whose meaning is more general than "Gene Knock-In Techniques".
Below are MeSH descriptors whose meaning is more specific than "Gene Knock-In Techniques".
This graph shows the total number of publications written about "Gene Knock-In Techniques" by people in this website by year, and whether "Gene Knock-In Techniques" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Gene Knock-In Techniques" by people in Profiles.
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A Knockin Model with the Mouse Equivalent to the c.2299delG Mutation in Usherin Exhibits Early-Onset Hearing Loss and Progressive Retinal Degeneration. Adv Exp Med Biol. 2025; 1468:253-257.
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Downregulation of rhodopsin is an effective therapeutic strategy in ameliorating peripherin-2-associated inherited retinal disorders. Nat Commun. 2024 Jun 04; 15(1):4756.
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Nonsense Variant PRDM16-Q187X Causes Impaired Myocardial Development and TGF-ß Signaling Resulting in Noncompaction Cardiomyopathy in Humans and Mice. Circ Heart Fail. 2023 Dec; 16(12):e010351.
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Prph2 initiates outer segment morphogenesis but maturation requires Prph2/Rom1 oligomerization. Hum Mol Genet. 2019 02 01; 28(3):459-475.
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Biomechanical changes to Descemet's membrane precede endothelial cell loss in an early-onset murine model of Fuchs endothelial corneal dystrophy. Exp Eye Res. 2019 Mar; 180:18-22.
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Rom1 converts Y141C-Prph2-associated pattern dystrophy to retinitis pigmentosa. Hum Mol Genet. 2017 02 01; 26(3):509-518.
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The K153Del PRPH2 mutation differentially impacts photoreceptor structure and function. Hum Mol Genet. 2016 08 15; 25(16):3500-3514.
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Purinergic control of hippocampal circuit hyperexcitability in Dravet syndrome. Epilepsia. 2014 Feb; 55(2):245-55.