Nucleic Acid Hybridization
"Nucleic Acid Hybridization" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)
Descriptor ID |
D009693
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MeSH Number(s) |
E05.393.661 G02.111.611
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Concept/Terms |
Nucleic Acid Hybridization- Nucleic Acid Hybridization
- Acid Hybridization, Nucleic
- Acid Hybridizations, Nucleic
- Hybridization, Nucleic Acid
- Hybridizations, Nucleic Acid
- Nucleic Acid Hybridizations
Genomic Hybridization- Genomic Hybridization
- Genomic Hybridizations
- Hybridization, Genomic
- Hybridizations, Genomic
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Below are MeSH descriptors whose meaning is more general than "Nucleic Acid Hybridization".
Below are MeSH descriptors whose meaning is more specific than "Nucleic Acid Hybridization".
This graph shows the total number of publications written about "Nucleic Acid Hybridization" by people in this website by year, and whether "Nucleic Acid Hybridization" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 1 | 1 |
2010 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
2014 | 0 | 1 | 1 |
2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nucleic Acid Hybridization" by people in Profiles.
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Label-free, zeptomole cancer biomarker detection by surface-enhanced fluorescence on nanoporous gold disk plasmonic nanoparticles. J Biophotonics. 2015 Oct; 8(10):855-63.
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Mechanically resolving noncovalent bonds using acoustic radiation force. Chem Commun (Camb). 2014 Sep 25; 50(74):10786-9.
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Rare target enrichment for ultrasensitive PCR detection using cot-rehybridization and duplex-specific nuclease. Anal Biochem. 2012 Feb 01; 421(1):81-5.
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The endoplasmic reticulum stress response factor CHOP-10 protects against hypoxia-induced neuronal death. J Biol Chem. 2010 Jul 09; 285(28):21329-40.
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Microbial identification by immunohybridization assay of artificial RNA labels. J Microbiol Methods. 2002 May; 49(3):301-6.