"Liver X Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nuclear receptors that bind OXYSTEROLS and function as heterodimers with RETINOID X RECEPTORS. They have important functions in regulating cholesterol homeostasis, ENERGY METABOLISM; INFLAMMATION; and the immune response.
| Descriptor ID |
D000071518
|
| MeSH Number(s) |
D12.776.260.531 D12.776.826.194
|
| Concept/Terms |
Liver X Receptors- Liver X Receptors
- Nuclear Oxysterol Receptors
- Oxysterol Receptors, Nuclear
- Liver X Receptor
Liver X Receptor Alpha- Liver X Receptor Alpha
- Liver X Receptor-Alpha
- NR1H3 Protein
- LXRalpha Protein
- Nuclear Orphan Receptor LXR-Alpha
- Nuclear Orphan Receptor LXR Alpha
- Oxysterols Receptor LXR-Alpha
- LXR-Alpha, Oxysterols Receptor
- Oxysterols Receptor LXR Alpha
- Nuclear Receptor Subfamily 1, Group H, Member 3
- LXR-Alpha Protein
- LXR Alpha Protein
Liver X Receptor Beta- Liver X Receptor Beta
- Liver X Receptor-Beta
- Nuclear Receptor Subfamily 1, Group H, Member 2
- Oxysterols Receptor LXR-Beta
- LXR-Beta, Oxysterols Receptor
- Oxysterols Receptor LXR Beta
- LXRbeta Protein
- NR1H2 Protein
|
Below are MeSH descriptors whose meaning is more general than "Liver X Receptors".
Below are MeSH descriptors whose meaning is more specific than "Liver X Receptors".
This graph shows the total number of publications written about "Liver X Receptors" by people in this website by year, and whether "Liver X Receptors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 3 | 3 |
| 2016 | 2 | 0 | 2 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Liver X Receptors" by people in Profiles.
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Liver X Receptor Inverse Agonist GAC0001E5 Impedes Glutaminolysis and Disrupts Redox Homeostasis in Breast Cancer Cells. Biomolecules. 2023 02 10; 13(2).
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Ablation of Liver X receptor ? in mice leads to overactive macrophages and death of spiral ganglion neurons. Hear Res. 2022 09 01; 422:108534.
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Loss of liver X receptor ? in astrocytes leads to anxiety-like behaviors via regulating synaptic transmission in the medial prefrontal cortex in mice. Mol Psychiatry. 2021 11; 26(11):6380-6393.
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Novel Liver X Receptor Ligand GAC0001E5 Disrupts Glutamine Metabolism and Induces Oxidative Stress in Pancreatic Cancer Cells. Int J Mol Sci. 2020 Dec 17; 21(24).
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Retinal and optic nerve degeneration in liver X receptor ? knockout mice. Proc Natl Acad Sci U S A. 2019 08 13; 116(33):16507-16512.
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Liver X receptor ? regulates the development of the dentate gyrus and autistic-like behavior in the mouse. Proc Natl Acad Sci U S A. 2018 03 20; 115(12):E2725-E2733.
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Ablation of Liver X receptors a and ? leads to spontaneous peripheral squamous cell lung cancer in mice. Proc Natl Acad Sci U S A. 2016 07 05; 113(27):7614-9.
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Liver X Receptor ? Is Involved in Formalin-Induced Spontaneous Pain. Mol Neurobiol. 2017 03; 54(2):1467-1481.
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Liver X receptor ? controls thyroid hormone feedback in the brain and regulates browning of subcutaneous white adipose tissue. Proc Natl Acad Sci U S A. 2015 Nov 10; 112(45):14006-11.
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The emerging roles of liver X receptors and their ligands in cancer. Expert Opin Ther Targets. 2016; 20(1):61-71.