"NF-kappa B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Ubiquitous, inducible, nuclear transcriptional activator that binds to enhancer elements in many different cell types and is activated by pathogenic stimuli. The NF-kappa B complex is a heterodimer composed of two DNA-binding subunits: NF-kappa B1 and relA.
| Descriptor ID |
D016328
|
| MeSH Number(s) |
D12.776.260.600 D12.776.660.600 D12.776.930.600
|
| Concept/Terms |
NF-kappa B- NF-kappa B
- kappa B Enhancer Binding Protein
- NF-kappaB
- NF kappaB
- Transcription Factor NF-kB
- Factor NF-kB, Transcription
- NF-kB, Transcription Factor
- Transcription Factor NF kB
- NF-kB
- NF kB
- Immunoglobulin Enhancer-Binding Protein
- Enhancer-Binding Protein, Immunoglobulin
- Immunoglobulin Enhancer Binding Protein
- Nuclear Factor kappa B
|
Below are MeSH descriptors whose meaning is more general than "NF-kappa B".
Below are MeSH descriptors whose meaning is more specific than "NF-kappa B".
This graph shows the total number of publications written about "NF-kappa B" by people in this website by year, and whether "NF-kappa B" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 1 | 2 |
| 2024 | 0 | 1 | 1 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "NF-kappa B" by people in Profiles.
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Cirsii Herba glycoprotein promotes macrophage M1 polarization through MAPK and NF-?B signaling pathways via interaction with TLR4. Int J Biol Macromol. 2025 Mar; 296:139687.
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IL-1ß mediated fibroblast-neutrophil crosstalk promotes inflammatory environment in skin lesions of SLE. Clin Immunol. 2024 Dec; 269:110396.
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MyD88-mediated signaling intercedes in neurogenic muscle atrophy through multiple mechanisms. FASEB J. 2021 08; 35(8):e21821.
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Fusobacterium nucleatum Secretes Outer Membrane Vesicles and Promotes Intestinal Inflammation. mBio. 2021 Mar 02; 12(2).
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NF-?B inhibitor with Temozolomide results in significant apoptosis in glioblastoma via the NF-?B(p65) and actin cytoskeleton regulatory pathways. Sci Rep. 2020 08 07; 10(1):13352.
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Structural and cellular mechanisms of peptidyl-prolyl isomerase Pin1-mediated enhancement of Tissue Factor gene expression, protein half-life, and pro-coagulant activity. Haematologica. 2018 06; 103(6):1073-1082.
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Multifaceted Role of BTLA in the Control of CD8+ T-cell Fate after Antigen Encounter. Clin Cancer Res. 2017 Oct 15; 23(20):6151-6164.
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Targeting estrogen receptor ? in microglia and T cells to treat experimental autoimmune encephalomyelitis. Proc Natl Acad Sci U S A. 2013 Feb 26; 110(9):3543-8.